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Ref Type
Authors J. Lickliter, L. Mileshkin, M. Voskoboynik, M. Millward, A. Freimund, T. Meniawy, T. Tang, R. Wei, M. Li, V. Paton
Title Dose escalation/expansion study to investigate the safety, pharmacokinetics, food effect, and antitumor activity of BGB-290 in patients with advanced solid tumors
Journal Ann Oncol
Abstract Text Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 368PD


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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown female reproductive organ cancer not applicable Pamiparib Phase I Actionable In a Phase I trial, Pamiparib (BGB-290) treatment resulted in objective response in 43% (10/23) of patients with gynecological cancer (Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 368PD; NCT02361723). detail...