Reference Detail

Ref Type
PMID
Authors D. Katalinic, I. Aleric, A. Vcev
Title Benefit of oral monotherapy with pazopanib in metastatic gastroenteropancreatic neuroendocrine tumours
Journal Annals of Oncology
Vol 28
Issue
Date
URL http://www.esmo.org/Conferences/ESMO-2017-Congress/Abstracts
Abstract Text Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 446P

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown gastrointestinal neuroendocrine tumor not applicable Pazopanib Clinical Study Actionable In a clinical study, Votrient (pazopanib) treatment in patients with gastroenteropancreatic neuroendocrine tumors resulted in an overall response rate of 24% (19/124), stable disease in 39.5% (49/124), a progression free survival of 36% at six months, and a median overall survival of 10.2 months (Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 446P). detail...