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| NCT ID | NCT02098343 |
| Title | p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246 |
| Recruitment | Completed |
| Gender | female |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Aprea Therapeutics AB |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | GBR | FRA | ESP | DEU | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCLA | Los Angeles | California | 90095 | United States | Details | |
| University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Oregon Health & Science University | Portland | Oregon | 97239 | United States | Details | |
| The University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| UPMC Hillman Cancer Center, Magee-Womens Hospital | Pittsburgh | Pennsylvania | 15213 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| Parkland, UT Southwestern Medical Center | Dallas | Texas | 75390 | United States | Details | |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | United States | Details | |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Massey Cancer Center, Virginia Commonwealth University | Richmond | Virginia | 23298 | United States | Details | |
| Swedish Cancer Institute | Seattle | Washington | 98104 | United States | Details | |
| Antwerp University Hospital | Antwerpen | 2650 | Belgium | Details | ||
| Institut Jules Bordet | Brussels | 1000 | Belgium | Details | ||
| Cliniques Universitaires Saint Luc | Brussels | B-1200 | Belgium | Details | ||
| Medische oncologie, Universitair Ziekenhuis Gent | Gent | 9000 | Belgium | Details | ||
| Leuven University Hospitals | Leuven | B-3000 | Belgium | Details | ||
| Centre Léon Bérard | Lyon | 69373 | France | Details | ||
| Centre Hospitalier Lyon Sud | Lyon | 69495 | France | Details | ||
| Centre Catherine de Sienne | Nantes | 44202 | France | Details | ||
| Institut Curie | Paris | 75005 | France | Details | ||
| Hôpital des Diaconesses (Site Reuilly) | Paris | 75012 | France | Details | ||
| Centre Paul Strass | Strasbourg | 67065 | France | Details | ||
| Institut Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Praxisklinik, Krebsheilkunde für Frauen | Berlin | 10367 | Germany | Details | ||
| Charité Campus Virchow-Klinikum | Berlin | 13353 | Germany | Details | ||
| Universitätsklinikum Carl Gustav Carus | Dresden | 01307 | Germany | Details | ||
| Universitätsklinikum Hamburg-Eppendorf | Hamburg | 20246 | Germany | Details | ||
| Universitätsfrauenklinik Ulm | Ulm | 89075 | Germany | Details | ||
| Academisch Medisch Centrum | Amsterdam | 1105 AZ | Netherlands | Details | ||
| Universitair Medisch Centrum Groningen | Groningen | 9700 RB | Netherlands | Details | ||
| Leids Universitair Medisch Centrum | Leiden | 2300 RC | Netherlands | Details | ||
| Academisch Ziekenhuis Maastricht | Maastricht | 6229 HX | Netherlands | Details | ||
| Institut Català d'Oncologia, Hospital Germans Trias i Pujol | Badalona | 08916 | Spain | Details | ||
| Hospital Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitario Reina Sofia | Córdoba | 14004 | Spain | Details | ||
| Centro Oncologico MD Anderson | Madrid | 28033 | Spain | Details | ||
| Hospital Universitario Ramón y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Universitario Fundación Jiménez Díaz | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario HM Sanchinarro | Madrid | 28050 | Spain | Details | ||
| Hospital Universitario Virgen de la Victoria | Málaga | 29010 | Spain | Details | ||
| Hospital Clinico Universitario de Valencia | Valencia | 46010 | Spain | Details | ||
| Hospital Universitario Araba | Vitoria-Gasteiz | 01009 | Spain | Details | ||
| Hospital Clínico Universitario Lozano Blesa | Zaragosa | 50009 | Spain | Details | ||
| Karolinska University Hospital | Stockholm | SE-171 76 | Sweden | Details | ||
| Bristol Haematology & Oncology Centre, University Hospitals Bristol | Bristol | BS2 8ED | United Kingdom | Details | ||
| Cambridge Cancer Trials Centre, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital | Cambridge | CB2 0QQ | United Kingdom | Details | ||
| Edinburgh Cancer Research Centre, The University of Edinburgh | Edinburgh | EH4 2XR | United Kingdom | Details | ||
| The Clatterbridge Cancer Center NHS Foundation Trust | Liverpool | CH63 4JY | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust | London | SM2 5PT | United Kingdom | Details | ||
| Imperial College London, Hammersmith Hospital Campus | London | W12 0NN | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details |