Clinical Trial Detail


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NCT ID NCT02098343
Title p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246
Recruitment Completed
Gender female
Phase Phase Ib/II
Variant Requirements Yes
Sponsors Aprea Therapeutics AB

ovarian carcinoma


Carboplatin + Doxorubicin

APR-246 + Carboplatin + Doxorubicin

Age Groups: adult | senior
Covered Countries USA | FRA | ESP | DEU | BEL

Facility Status City State Zip Country Details
UCLA Los Angeles California 90095 United States Details
University of Chicago Chicago Illinois 60637 United States Details
Massachusetts General Hospital Boston Massachusetts 02114 United States Details
Dana Farber Cancer Institute Boston Massachusetts 02215 United States Details
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 United States Details
Oregon Health & Science University Portland Oregon 97239 United States Details
The University of Pennsylvania Philadelphia Pennsylvania 19104 United States Details
Fox Chase Cancer Center Philadelphia Pennsylvania 19111 United States Details
UPMC Hillman Cancer Center, Magee-Womens Hospital Pittsburgh Pennsylvania 15213 United States Details
Vanderbilt University Medical Center Nashville Tennessee 37232 United States Details
Parkland, UT Southwestern Medical Center Dallas Texas 75390 United States Details
University of Texas Southwestern Medical Center Dallas Texas 75390 United States Details
The University of Texas MD Anderson Cancer Center Houston Texas 77030 United States Details
Massey Cancer Center, Virginia Commonwealth University Richmond Virginia 23298 United States Details
Swedish Cancer Institute Seattle Washington 98104 United States Details
Antwerp University Hospital Antwerpen 2650 Belgium Details
Institut Jules Bordet Brussels 1000 Belgium Details
Cliniques Universitaires Saint Luc Brussels B-1200 Belgium Details
Medische oncologie, Universitair Ziekenhuis Gent Gent 9000 Belgium Details
Leuven University Hospitals Leuven B-3000 Belgium Details
Centre Léon Bérard Lyon 69373 France Details
Centre Hospitalier Lyon Sud Lyon 69495 France Details
Centre Catherine de Sienne Nantes 44202 France Details
Institut Curie Paris 75005 France Details
Hôpital des Diaconesses (Site Reuilly) Paris 75012 France Details
Centre Paul Strass Strasbourg 67065 France Details
Institut Gustave Roussy Villejuif 94805 France Details
Praxisklinik, Krebsheilkunde für Frauen Berlin 10367 Germany Details
Charité Campus Virchow-Klinikum Berlin 13353 Germany Details
Universitätsklinikum Carl Gustav Carus Dresden 01307 Germany Details
Universitätsklinikum Hamburg-Eppendorf Hamburg 20246 Germany Details
Universitätsfrauenklinik Ulm Ulm 89075 Germany Details
Academisch Medisch Centrum Amsterdam 1105 AZ Netherlands Details
Universitair Medisch Centrum Groningen Groningen 9700 RB Netherlands Details
Leids Universitair Medisch Centrum Leiden 2300 RC Netherlands Details
Academisch Ziekenhuis Maastricht Maastricht 6229 HX Netherlands Details
Institut Català d'Oncologia, Hospital Germans Trias i Pujol Badalona 08916 Spain Details
Hospital Vall d'Hebron Barcelona 08035 Spain Details
Hospital Universitario Reina Sofia Córdoba 14004 Spain Details
Centro Oncologico MD Anderson Madrid 28033 Spain Details
Hospital Universitario Ramón y Cajal Madrid 28034 Spain Details
Hospital Universitario Fundación Jiménez Díaz Madrid 28040 Spain Details
Hospital Universitario HM Sanchinarro Madrid 28050 Spain Details
Hospital Universitario Virgen de la Victoria Málaga 29010 Spain Details
Hospital Clinico Universitario de Valencia Valencia 46010 Spain Details
Hospital Universitario Araba Vitoria-Gasteiz 01009 Spain Details
Hospital Clínico Universitario Lozano Blesa Zaragosa 50009 Spain Details
Karolinska University Hospital Stockholm SE-171 76 Sweden Details
Bristol Haematology & Oncology Centre, University Hospitals Bristol Bristol BS2 8ED United Kingdom Details
Cambridge Cancer Trials Centre, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital Cambridge CB2 0QQ United Kingdom Details
Edinburgh Cancer Research Centre, The University of Edinburgh Edinburgh EH4 2XR United Kingdom Details
The Clatterbridge Cancer Center NHS Foundation Trust Liverpool CH63 4JY United Kingdom Details
The Royal Marsden NHS Foundation Trust London SM2 5PT United Kingdom Details
Imperial College London, Hammersmith Hospital Campus London W12 0NN United Kingdom Details
The Christie NHS Foundation Trust Manchester M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from for the field