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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Unknown unknown Onvansertib ovarian carcinoma not applicable detail...
Unknown unknown BMS-906024 ovarian carcinoma not applicable detail...
Unknown unknown NMS-P715 ovarian carcinoma not applicable detail...
BRAF V600X PIK3CA H1047X Bevacizumab + Pegylated liposomal-doxorubicin + Temsirolimus ovarian carcinoma predicted - sensitive detail...
TP53 I195* TP53 R248Q ReACp53 ovarian carcinoma sensitive detail...
TP53 Y234C ReACp53 ovarian carcinoma sensitive detail...
TP53 Y327L ReACp53 ovarian carcinoma sensitive detail...
TP53 inact mut ReACp53 ovarian carcinoma sensitive detail...
Unknown unknown VS-4718 ovarian carcinoma not applicable detail...
Unknown unknown Rucaparib ovarian carcinoma not applicable detail...
Unknown unknown Denileukin diftitox + Sirolimus ovarian carcinoma no benefit detail...
Unknown unknown Gemcitabine + MU380 ovarian carcinoma not applicable detail...
RAD51C R193* Rucaparib ovarian carcinoma predicted - sensitive detail...
RAD51C H192_R193delinsGG RAD51C R193* RAD51C R193L RAD51C R193W Rucaparib ovarian carcinoma predicted - resistant detail...
RAD51C R193L Rucaparib ovarian carcinoma resistant detail...
RAD51C R193W Rucaparib ovarian carcinoma resistant detail...
RAD51C H192_R193delinsGG Rucaparib ovarian carcinoma resistant detail...
RAD51C R193L Niraparib ovarian carcinoma resistant detail...
RAD51C R193W Niraparib ovarian carcinoma resistant detail...
RAD51C H192_R193delinsGG Niraparib ovarian carcinoma resistant detail...
RAD51C R193L Olaparib ovarian carcinoma resistant detail...
RAD51C R193W Olaparib ovarian carcinoma resistant detail...
RAD51C H192_R193delinsGG Olaparib ovarian carcinoma resistant detail...
RAD51C R193L Talazoparib ovarian carcinoma resistant detail...
RAD51C R193W Talazoparib ovarian carcinoma resistant detail...
RAD51C H192_R193delinsGG Talazoparib ovarian carcinoma resistant detail...
RAD51C R193W Veliparib ovarian carcinoma resistant detail...
RAD51C H192_R193delinsGG Veliparib ovarian carcinoma resistant detail...
RAD51D G258Sfs*50 Rucaparib ovarian carcinoma sensitive detail...
RAD51D S257_R259delinsK RAD51D G258Sfs*50 Rucaparib ovarian carcinoma predicted - resistant detail...
Unknown unknown Disarib ovarian carcinoma not applicable detail...
Unknown unknown Topotecan + Veliparib ovarian carcinoma not applicable detail...
Unknown unknown SKLB-23bb ovarian carcinoma not applicable detail...
Unknown unknown BI 853520 ovarian carcinoma not applicable detail...
Unknown unknown Motolimod + Pegylated liposomal-doxorubicin ovarian carcinoma no benefit detail...
TP53 mutant Adavosertib ovarian carcinoma predicted - sensitive detail...
Unknown unknown Triapine ovarian carcinoma not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT00989651 Phase I Bevacizumab + Veliparib Carboplatin Paclitaxel Cisplatin Carboplatin, Paclitaxel, Bevacizumab, and ABT-888 in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Active, not recruiting USA 0
NCT01174121 Phase II Pembrolizumab Cyclophosphamide + Fludarabine Aldesleukin Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer Suspended USA 0
NCT01248962 Phase II Carboplatin Standard Infusion Carboplatin Versus Prophylactic Extended Infusion Carboplatin in Patients With Patients With Recurrent, Ovary, Fallopian Tube, and Primary Peritoneal Cancer Completed USA 0
NCT01281514 Phase I Carboplatin + Everolimus + Pegylated liposomal-doxorubicin Carboplatin, Pegylated Liposomal Doxorubicin Hydrochloride, and Everolimus in Treating Patients With Relapsed Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer Completed USA 0
NCT01504126 Phase I Propranolol Beta-Blocker / Ovarian Completed USA 0
NCT01607905 Phase I Selinexor Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced or Metastatic Solid Tumor Cancer Completed USA | CAN 1
NCT01669798 Phase II Nintedanib BIBF 1120 in Bevacizumab Resistant, Persistent, or Recurrent Epithelial Ovarian Cancer Completed USA 0
NCT01849874 Phase III Binimetinib A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer Active, not recruiting USA | CAN 18
NCT01936974 Phase II Bevacizumab + Cisplatin + Gemcitabine Bevacizumab + Gemcitabine + Oxaliplatin Bevacizumab + Carboplatin + Gemcitabine Bevacizumab + Gemcitabine (PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and Peritoneal Carcinoma Terminated USA 0
NCT01940172 Phase I Conatumumab Birinapant Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer Completed USA 0
NCT01974765 Phase II Enzalutamide Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior Therapies Active, not recruiting USA 0
NCT02042430 Phase I Epacadostat INCB024360 Before Surgery in Treating Patients With Newly Diagnosed Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Active, not recruiting USA 0
NCT02059265 Phase II Dasatinib Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer Active, not recruiting USA 0
NCT02098343 Phase Ib/II Carboplatin + Doxorubicin APR-246 + Carboplatin + Doxorubicin p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246 Completed USA 7
NCT02101775 Phase II Gemcitabine Adavosertib + Gemcitabine Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Active, not recruiting USA | CAN 1
NCT02101788 Phase II Topotecan Letrozole + Paclitaxel + Pegylated liposomal-doxorubicin + Tamoxifen Trametinib Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer Active, not recruiting USA 1
NCT02121990 Phase I Bevacizumab + Cisplatin + Olaparib + Paclitaxel Dose-Escalation Study of Intraperitoneal (IP) Cisplatin, IV/IP Paclitaxel, IV Bevacizumab, and Oral Olaparib for Newly Diagnosed Ovarian, Primary Peritoneal, and Fallopian Tube Cancer Completed USA 0
NCT02122185 Phase II Metformin Carboplatin + Docetaxel + Paclitaxel Metformin Hydrochloride and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Recruiting USA 0
NCT02166905 Phase Ib/II Poly ICLC Rasdegafusp alfa Epacadostat DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission Active, not recruiting USA 0
NCT02270372 Phase I Varlilumab ONT-10 Study of ONT-10 and Varlilumab to Treat Advanced Ovarian or Breast Cancer Completed USA 0
NCT02283658 Phase II Everolimus + Letrozole Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer Completed USA 0
NCT02431559 Phase Ib/II Aldoxorubicin + Durvalumab + Motolimod A Phase 1/2 Study of Motolimod (VTX-2337) and MEDI4736 in Subjects With Recurrent, Platinum-Resistant Ovarian Cancer for Whom Pegylated Liposomal Doxorubicin (PLD) is Indicated Active, not recruiting USA 1
NCT02440425 Phase II Paclitaxel Pembrolizumab Dose Dense Paclitaxel With Pembrolizumab (MK-3475) in Platinum Resistant Ovarian Cancer Active, not recruiting USA 0
NCT02444793 Phase I Mogamulizumab + Utomilumab A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors Terminated USA 0
NCT02459301 Phase I Monalizumab Dose-Ranging Study of IPH2201 in Patients With High Grade Serious CA of Ovarian, Fallopian Tube or Peritoneal Origin Completed CAN 0
NCT02470585 Phase III Carboplatin Paclitaxel Veliparib Veliparib With Carboplatin and Paclitaxel and as Continuation Maintenance Therapy in Subjects With Newly Diagnosed Stage III or IV, High-grade Serous, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Active, not recruiting USA 10
NCT02485990 Phase Ib/II Olaparib Tremelimumab Study of Tremelimumab Alone or Combined With Olaparib for Patients With Persistent EOC (Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma) Terminated USA 0
NCT02489006 Phase II Olaparib A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer Recruiting CAN 3
NCT02520115 Phase I Dexamethasone Valproic acid Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian Cancer Completed USA 0
NCT02571725 Phase Ib/II Olaparib + Tremelimumab PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer Active, not recruiting USA 0
NCT02608684 Phase II Cisplatin + Gemcitabine + Pembrolizumab A Study of Pembrolizumab With Standard Treatment in Patients With Recurrent Platinum-resistant Ovarian Cancer Active, not recruiting USA 0
NCT02657928 Phase II Letrozole + Ribociclib Ribociclib and Letrozole in Treating Patients With Relapsed ER Positive Ovarian, Fallopian Tube, Primary Peritoneal, or Endometrial Cancer Active, not recruiting USA 0
NCT02659241 Phase I Adavosertib A Pilot Study of Induction Wee1 Inhibition in Ovarian Cancer Recruiting USA 0
NCT02661815 Phase I Paclitaxel + Ricolinostat Bevacizumab A Phase 1b Study of Weekly Paclitaxel And Oral Ricolinostat For The Treatment Of Recurrent Platinum Resistant Ovarian, Primary Peritoneal, Or Fallopian Tube Cancer Terminated USA 0
NCT02665416 Phase I RO5520985 + Selicrelumab Bevacizumab + Selicrelumab Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab in Metastatic Solid Tumors Completed USA | CAN 5
NCT02759588 Phase Ib/II GL-ONC1 GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent Ovarian Cancer Active, not recruiting USA 0
NCT02764333 Phase II Durvalumab + TPIV 200 TPIV200/huFR-1 (A Multi-Epitope Anti-Folate Receptor Vaccine) Plus Anti-PD-L1 MEDI4736 (Durvalumab) in Patients With Platinum Resistant Ovarian Cancer Completed USA 0
NCT02835833 Phase I Bevacizumab + Nintedanib Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors Completed USA 0
NCT02953457 Phase II Durvalumab + Olaparib + Tremelimumab Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation Active, not recruiting USA 0
NCT02960594 Phase I INO-1400 + INO-9012 INO-1400 hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse Completed USA 0
NCT03017131 Phase I Aldesleukin + Cyclophosphamide + Decitabine + NY-ESO-1-c259T Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Active, not recruiting USA 0
NCT03029403 Phase II Cyclophosphamide + DPX-Survivac + Pembrolizumab Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer Recruiting CAN 0
NCT03435640 Phase Ib/II NKTR-214 + NKTR-262 Nivolumab + NKTR-214 + NKTR-262 A Study of NKTR-262 in Combination With NKTR-214 and With NKTR-214 Plus Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumor Malignancies Active, not recruiting USA 0
NCT03517488 Phase I XmAb20717 A Study of XmAb20717 in Subjects With Selected Advanced Solid Tumors (DUET-2) Recruiting USA 0
NCT03878849 Phase II E7449 Investigation of 2X-121 in Patients With Advanced Ovarian Cancer Selected by the 2X-121 DRP (PREDICT 2X-121) Recruiting USA 0
NCT03924245 Phase Ib/II Entinostat Entinostat + Olaparib Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers Recruiting USA 0
NCT03957096 Phase I SGN-CD47M A Safety Study of SGN-CD47M in Patients With Solid Tumors Terminated USA 0
NCT04096638 Phase I Nivolumab + SB 11285 SB 11285 Evaluating Safety and Efficacy of SB 11285 Alone and in Combination With Nivolumab in Patients With Advanced Solid Tumors Recruiting USA 0
NCT04140526 Phase Ib/II ONC-392 ONC-392 + Pembrolizumab Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC Recruiting USA 0
NCT04434560 Phase II Ipilimumab + Nivolumab Neoadjuvant Immunotherapy in Brain Metastases Recruiting USA 0
NCT04498117 Phase III Carboplatin + Oregovomab + Paclitaxel Carboplatin + Paclitaxel Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery (FLORA-5) Recruiting USA | CAN 1