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INO-1400 is a plasmid encoding hTERT with two mutations, which may increase anti-tumor immune response against hTERT-expressing tumor cells (NCI Drug Dictionary).
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|INO-1400||INO-1400 is a plasmid encoding TERT with two mutations, which may increase anti-tumor immune response against hTERT-expressing tumor cells (PMID: 29081765).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT02960594||Phase I||INO-1400 + INO-9012 INO-1400||hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse||Completed|