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| NCT ID | NCT03165734 |
| Title | A Phase 2/3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis (PACIFICA) |
| Acronym | PACIFICA |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | CTI BioPharma |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | GBR | FRA | ESP | DEU | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham, (UAB) Hospital, Comprehensive Cancer Center | ACTIVE_NOT_RECRUITING | Birmingham | Alabama | 35294 | United States | Details |
| Mayo Clinic Hospital | COMPLETED | Phoenix | Arizona | 85054 | United States | Details |
| City of Hope | ACTIVE_NOT_RECRUITING | Duarte | California | 91010 | United States | Details |
| USC Norris Comprehensive Cancer Center | COMPLETED | Los Angeles | California | 90033 | United States | Details |
| UCLA David Geffen School of Medicine | COMPLETED | Los Angeles | California | 90095 | United States | Details |
| University of Colorado Cancer Center | COMPLETED | Aurora | Colorado | 80045 | United States | Details |
| Rocky Mountain Cancer Centers (US Oncology/McKesson) | COMPLETED | Boulder | Colorado | 80303 | United States | Details |
| Yale School of Medicine | COMPLETED | New Haven | Connecticut | 06510 | United States | Details |
| Georgetown University Hospital | COMPLETED | Washington | District of Columbia | 20007 | United States | Details |
| George Washington University-Medical Faculty Associates | COMPLETED | Washington | District of Columbia | 20037 | United States | Details |
| Cleveland Clinic Florida | COMPLETED | Weston | Florida | 33331 | United States | Details |
| Northwestern Memorial Hospital | COMPLETED | Chicago | Illinois | 60611 | United States | Details |
| Rush University Medical Center | COMPLETED | Chicago | Illinois | 60612 | United States | Details |
| The University of Chicago Medical Center | COMPLETED | Chicago | Illinois | 60637 | United States | Details |
| University of Kansas Cancer Center and Medical Pavilion | COMPLETED | Westwood | Kansas | 66205 | United States | Details |
| Ochsner Medical Center | COMPLETED | New Orleans | Louisiana | 70121 | United States | Details |
| Saint Agnes Hospital | ACTIVE_NOT_RECRUITING | Baltimore | Maryland | 21229 | United States | Details |
| Johns Hopkins University | COMPLETED | Baltimore | Maryland | 21287 | United States | Details |
| American Oncology Partners of Maryland, PA | COMPLETED | Bethesda | Maryland | 20817 | United States | Details |
| Regional Cancer Care Associates LLC - CCBD Division | WITHDRAWN | Bethesda | Maryland | 20817 | United States | Details |
| Maryland Oncology Hematology, PA- Columbia | COMPLETED | Columbia | Maryland | 21044 | United States | Details |
| Dana Farber Cancer Institute, Massachusetts General Hospital | WITHDRAWN | Boston | Massachusetts | 02215 | United States | Details |
| Michigan Medicine Hematology Clinic-Rogel Cancer Center | COMPLETED | Ann Arbor | Michigan | 48109 | United States | Details |
| Cancer and Hematology Centers of Western Michigan | COMPLETED | Grand Rapids | Michigan | 49546 | United States | Details |
| Washington University School of Medicine-Siteman Cancer Center | COMPLETED | Saint Louis | Missouri | 63110 | United States | Details |
| Comprehensive Cancer Centers of Nevada- Twain Office | ACTIVE_NOT_RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| Hackensack University Medical Center | ACTIVE_NOT_RECRUITING | Hackensack | New Jersey | 07601 | United States | Details |
| Memorial Sloan-Kettering Cancer Center- Commack | ACTIVE_NOT_RECRUITING | Commack | New York | 11725 | United States | Details |
| Columbia University Medical Center | COMPLETED | New York | New York | 10017 | United States | Details |
| Weill Cornell Medical College | ACTIVE_NOT_RECRUITING | New York | New York | 10021 | United States | Details |
| Icahn School of Medicine at Mount Sinai | ACTIVE_NOT_RECRUITING | New York | New York | 10029 | United States | Details |
| Memorial Sloan -Kettering Cancer Center | ACTIVE_NOT_RECRUITING | New York | New York | 10065 | United States | Details |
| University of Rochester | COMPLETED | Rochester | New York | 14642 | United States | Details |
| Duke University Hospital | COMPLETED | Durham | North Carolina | 27710 | United States | Details |
| Cleveland Clinic | COMPLETED | Cleveland | Ohio | 44106 | United States | Details |
| Ohio State University Comprehensive Cancer Center | ACTIVE_NOT_RECRUITING | Columbus | Ohio | 43210 | United States | Details |
| Oregon Health and Science University | ACTIVE_NOT_RECRUITING | Portland | Oregon | 97239-3098 | United States | Details |
| UPMC Hillman Cancer Center | COMPLETED | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| The Sarah Cannon Research Institute-Tennessee Oncology | COMPLETED | Nashville | Tennessee | 37203 | United States | Details |
| The University of Texas MD Anderson Cancer Center | COMPLETED | Houston | Texas | 77030 | United States | Details |
| Mays Cancer Center | COMPLETED | San Antonio | Texas | 78229 | United States | Details |
| Texas Oncology- San Antonio | COMPLETED | San Antonio | Texas | 78240 | United States | Details |
| University of Utah - Huntsman Cancer Institute | COMPLETED | Salt Lake City | Utah | 84112 | United States | Details |
| Fred Hutchinson Cancer Research Center | COMPLETED | Seattle | Washington | 98109 | United States | Details |
| Westmead Hospital | RECRUITING | Sydney | New South Wales | Australia | Details | |
| Alfred Hospital, Malignant Hematology and Stem Cell Transplantation Service | RECRUITING | Melbourne | Victoria | Australia | Details | |
| The Perth Blood Institute | RECRUITING | Perth | Western Australia | Australia | Details | |
| Republican Research Center for Radiation Medicine and Human Ecology | RECRUITING | Gomel | Belarus | Details | ||
| Grodno University Hospital | COMPLETED | Grodno | Belarus | Details | ||
| Minsk Scientific and Practical Center of Surgery, Transplantology and Hematology | RECRUITING | Minsk | Belarus | Details | ||
| University Clinical Centre of the Republic of Srpska | RECRUITING | Banja Luka | Bosnia and Herzegovina | Details | ||
| University Clinical Center of Sarajevo | RECRUITING | Sarajevo | Bosnia and Herzegovina | Details | ||
| University Multiprofile Hospital for Active Treatment "Dr. Georgi Stranski" | RECRUITING | Pleven | Bulgaria | Details | ||
| University Multiprofile Hospital for Active Treatment "Sveti Georgi", Plovdiv | RECRUITING | Plovdiv | Bulgaria | Details | ||
| Multiprofile Hospital for Active Treatment - Sofia, part of Military Medical Academy | RECRUITING | Sofia | Bulgaria | Details | ||
| Specialized Hospital for Active Treatment of Hematological Diseases | RECRUITING | Sofia | Bulgaria | Details | ||
| Multiprofile Hospital for Active Treatment "Sveta Marina" | RECRUITING | Varna | Bulgaria | Details | ||
| Tom Baker Cancer Center, Internal Medicine/Hematology | RECRUITING | Calgary | Alberta | T2N 4N2 | Canada | Details |
| University of Alberta | RECRUITING | Edmonton | Alberta | T2N 4N2 | Canada | Details |
| Providence Hematology - Vancouver | RECRUITING | Vancouver | British Columbia | V6Z 2A5 | Canada | Details |
| Eastern Regional Health Authority | RECRUITING | Saint John's | Newfoundland and Labrador | A1B 3V6 | Canada | Details |
| Nova Scotia Health Authority, Centre for Clinical Research | RECRUITING | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Jewish General Hospital; Clinical Research Unit | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| University Hospital Brno | RECRUITING | Brno | Czechia | Details | ||
| University Hospital Olomouc | RECRUITING | Olomouc | Czechia | Details | ||
| University Hospital Plzen | RECRUITING | Pilsen | Czechia | Details | ||
| University Hospital Kralovske Vinohrady, Clinic of Internal Hematology | RECRUITING | Prague | Czechia | Details | ||
| CHU Hôpital Amiens Sud | RECRUITING | Amiens | 80054 | France | Details | |
| La Conception Hospital | RECRUITING | Marseille | France | Details | ||
| CHU de Nimes - Hopital Universitaire Caremeau | RECRUITING | Nîmes | 30900 | France | Details | |
| Hôpital Saint-Louis | RECRUITING | Paris | France | Details | ||
| CHU Hopitaux de Bordeaux - Hôpital Haut-Lévêque | RECRUITING | Pessac | 33604 | France | Details | |
| Centre Hospitalier Lyon-Sud | RECRUITING | Pierre Benite | France | Details | ||
| University Hospital Center of Poitiers | RECRUITING | Poitiers | France | Details | ||
| Hautepierre Hospital | WITHDRAWN | Strasbourg | France | Details | ||
| Centre Hospitalier de Toulouse- Hôpital Purpan | WITHDRAWN | Toulouse | France | Details | ||
| JSC K. Eristavi National Center For Experimental and Clinical Surgery | RECRUITING | Tbilisi | Georgia | Details | ||
| LTD M.Zodelava's Hematology Center, Department of Hematology | RECRUITING | Tbilisi | Georgia | Details | ||
| LTD National Institute of Endocrinology | WITHDRAWN | Tbilisi | Georgia | Details | ||
| LTD S.Khechinashvili University Hospital | COMPLETED | Tbilisi | Georgia | Details | ||
| Malkhaz Katsiashvili Multiprofile Emergency Medicine Center LTD | RECRUITING | Tbilisi | Georgia | Details | ||
| Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic LLC | RECRUITING | Tbilisi | Georgia | Details | ||
| University Hospital Cologne, Department of Internal Medicine I, | WITHDRAWN | Cologne | Germany | Details | ||
| University Hospital Halle (Saale), Department of Internal Medicine IV - Hematology and Oncology | WITHDRAWN | Halle | Germany | Details | ||
| Johannes Wesling Hospital Minden, Department of Oncology and Hematology | WITHDRAWN | Minden | Germany | Details | ||
| Hospital rechts der Isar, Department of Internal Medicine III, Hematology and Oncology | WITHDRAWN | Munich | Germany | Details | ||
| University Hospital Ulm, Center for Internal Medicine, | WITHDRAWN | Ulm | Germany | Details | ||
| Semmelweis University SE ÁOK I. sz. Belgyógyászati Klinika | RECRUITING | Budapest | Hungary | Details | ||
| University of Debrecen Clinical Center (Debreceni Egyetem Klinikai Központ) | RECRUITING | Debrecen | Hungary | Details | ||
| Somogy Megyei Kaposi Mór Oktató Kórház | RECRUITING | Kaposvár | Hungary | Details | ||
| Bacs-Kiskun County Hospital, 2nd Department of Internal Medicine | WITHDRAWN | Kecskemét | Hungary | Details | ||
| Szabolcs-Szatmar-Bereg County Hospitals and University Teaching Hospital, Department of Hematology | RECRUITING | Nyíregyháza | Hungary | Details | ||
| Fejer County St. Gyorgy University Teaching Hospital, Department of Internal Medicine I | RECRUITING | Székesfehérvár | Hungary | Details | ||
| St. John's Medical College Hospital | RECRUITING | Bengaluru | India | Details | ||
| Lady Davis Carmel Medical Center, Department of Hematology, | RECRUITING | Haifa | Israel | Details | ||
| Hadassah Medical Center, Department of Hematology, | RECRUITING | Jerusalem | Israel | Details | ||
| Meir Medical Center, Hematology Institute and Blood Bank | RECRUITING | Kfar Saba | Israel | Details | ||
| Rabin Medical Center, Clinic for Myeloproliferative Disorders | RECRUITING | Petah-Tikva | Israel | Details | ||
| The Tel Aviv Sourasky Medical Center, Department of Internal Medicine | RECRUITING | Tel Aviv | Israel | Details | ||
| Cancer Institute "Giovanni Paolo II", IRCCS | RECRUITING | Bari | Italy | Details | ||
| Polyclinic S. Orsola-Malpighi | RECRUITING | Bologna | Italy | Details | ||
| ASST Spedali Civili Brescia, Hematology Unit | RECRUITING | Brescia | Italy | Details | ||
| Azienda Ospedaliero-Universitaria Careggi | RECRUITING | Florence | Italy | Details | ||
| Scientific Institute of Romagna for the Study and Treatment of Cancer (IRST), IRCCS | RECRUITING | Forlì | Italy | Details | ||
| Maggiore Polyclinic Hospital, Fondazione IRCCS Ca' Granda | RECRUITING | Milan | Italy | Details | ||
| ASST Monza - Ospedale San Gerardo | RECRUITING | Monza | Italy | Details | ||
| University Hospital "Federico II" | RECRUITING | Naples | Italy | Details | ||
| University Hospital "Maggiore della Carita" of Novara | RECRUITING | Novara | Italy | Details | ||
| United Hospitals Villa Sofia Cervello | RECRUITING | Palermo | Italy | Details | ||
| Polyclinic San Matteo, IRCCS | RECRUITING | Pavia | Italy | Details | ||
| Hospital "Infermi" of Rimini | COMPLETED | Rimini | Italy | Details | ||
| Umberto I Polyclinic of Rome | RECRUITING | Rome | Italy | Details | ||
| University Polyclinic Foundation "Agostino Gemelli" | RECRUITING | Rome | Italy | Details | ||
| ASST Sette Laghi Hospital | RECRUITING | Varese | Italy | Details | ||
| Pusan National University Hospital | RECRUITING | Busan | Korea, Republic of | Details | ||
| Kyungpook National University Hospital | RECRUITING | Daegu | Korea, Republic of | Details | ||
| Severance Hospital | RECRUITING | Seoul | 3722 | Korea, Republic of | Details | |
| Samsung Medical Center | RECRUITING | Seoul | Korea, Republic of | Details | ||
| Seoul National University Hospital | RECRUITING | Seoul | Korea, Republic of | Details | ||
| The Catholic University of Korea, St. Mary's Hospital | RECRUITING | Seoul | Korea, Republic of | Details | ||
| University Teaching Hospital in Bialystok | RECRUITING | Białystok | Poland | Details | ||
| University Clinical Center in Gdansk | RECRUITING | Gdańsk | Poland | Details | ||
| Andrzej Mielecki Independent Public Clinical Hospital of Medical University of Silesia in Katowice, Department of Hematology and Bone Marrow Transplantation | RECRUITING | Katowice | Poland | Details | ||
| Pratia Oncology Katowice | RECRUITING | Katowice | Poland | Details | ||
| University Hospital in Krakow | RECRUITING | Kraków | Poland | Details | ||
| Independent Public Teaching Hospital No.1 in Lublin, Department of Hematooncology, Bone Marrow Transplantation and Chemotherapy | RECRUITING | Lublin | Poland | Details | ||
| Jedrzej Sniadecki Specialist Hospital in Nowy Sacz, Department of Hematology | RECRUITING | Nowy Sącz | Poland | Details | ||
| Frederic Chopin Provincial Teaching Hospital No. 1 in Rzeszow, Department of Hematology, | COMPLETED | Rzeszów | Poland | Details | ||
| Nasz Lekarz Medical Outpatient Clinics Slawomir Jeka | RECRUITING | Toruń | Poland | Details | ||
| Institute of Hematology and Transfusion Medicine, Teaching Department of Hematology | RECRUITING | Warsaw | Poland | Details | ||
| Jan Mikulicz Radecki University Hospital in Wroclaw, Department and Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation | RECRUITING | Wrocław | Poland | Details | ||
| Nicolaus Copernicus Provincial Multispecialty Oncology and Traumatology Center in Lodz | RECRUITING | Łódź | Poland | Details | ||
| Onco Card Srl | RECRUITING | Braşov | Romania | Details | ||
| Coltea Clinical Hospital | RECRUITING | Bucharest | Romania | Details | ||
| Fundeni Clinical Institute | RECRUITING | Bucharest | Romania | Details | ||
| Prof. Dr. Ion Chiricuta" Institute of Oncology | RECRUITING | Cluj-Napoca | Romania | Details | ||
| City Clinical Hospital #40 | COMPLETED | Moscow | Russian Federation | Details | ||
| City Clinical Hospital n.a. V.V. Veresaev of the Moscow City Health | COMPLETED | Moscow | Russian Federation | Details | ||
| S.P. Botkin City Clinical Hospital | ACTIVE_NOT_RECRUITING | Moscow | Russian Federation | Details | ||
| Clinic UZI 4D, LLC | ACTIVE_NOT_RECRUITING | Pyatigorsk | Russian Federation | Details | ||
| Research Institute of Hematology and Transfusiology | ACTIVE_NOT_RECRUITING | Saint Petersburg | Russian Federation | Details | ||
| S.M. Kirov Military Medical Academy, Department and Clinic for Intermediate-Level Training in Internal Medicine, Hematology Division | ACTIVE_NOT_RECRUITING | Saint Petersburg | Russian Federation | Details | ||
| V.A. Almazov North-West Federal Medical Research Center, Institute of Oncology and Hematology, Scientific Department of Clinical Oncology | ACTIVE_NOT_RECRUITING | Saint Petersburg | Russian Federation | Details | ||
| V.D. Seredavin Samara Regional Clinical Hospital, Department of Hematology | WITHDRAWN | Samara | Russian Federation | Details | ||
| Bashkiria State Medical University, Department of Internal Medicine | COMPLETED | Ufa | Russian Federation | Details | ||
| Volgograd Regional Clinical Oncology Center | COMPLETED | Volgograd | Russian Federation | Details | ||
| Clinical Center of Serbia, Clinic of Hematology | RECRUITING | Belgrade | Serbia | Details | ||
| Clinical Center of Vojvodina, Clinic of Hematology | RECRUITING | Novi Sad | Serbia | Details | ||
| Hospital del Mar | RECRUITING | Barcelona, | Spain | Details | ||
| Hospital Clínic de Barcelona | RECRUITING | Barcelona | Spain | Details | ||
| University Hospital Vall d'Hebron | RECRUITING | Barcelona | Spain | Details | ||
| Hospital Universitario Ramón y Cajal | RECRUITING | Madrid | Spain | Details | ||
| University Hospital 12 de Octubre, Department of Hematology | RECRUITING | Madrid | Spain | Details | ||
| Morales Meseguer University General Hospital, Department of Hematology and Hemotherapy | RECRUITING | Murcia | Spain | Details | ||
| Clínica Universidad de Navarra | WITHDRAWN | Pamplona | Spain | Details | ||
| University Clinical Hospital of Salamanca, Department of Hematology | RECRUITING | Salamanca | Spain | Details | ||
| University Hospital Virgen del Rocio (HUVR) | RECRUITING | Seville | Spain | Details | ||
| University Clinical Hospital of Valencia, Department of Hematology and Medical Oncology | RECRUITING | Valencia | Spain | Details | ||
| Cherkasy Regional Oncology Dispensary of Cherkasy Oblast Council, Regional Treatment and Diagnostic Hematology Center, Department of Hematology | ACTIVE_NOT_RECRUITING | Cherkasy | Ukraine | Details | ||
| City Clinical Hospital #4" under Dnipro City Council | ACTIVE_NOT_RECRUITING | Dnipro | Ukraine | Details | ||
| Regional Clinical Hospital, Department of Hematology, | WITHDRAWN | Ivano-Frankivs'k | Ukraine | Details | ||
| Communal Non-profit enterprise "Regional Center of Oncology", Department of Hematology | ACTIVE_NOT_RECRUITING | Kharkiv | Ukraine | Details | ||
| Kyiv City Clinical Hospital #9, Hematology Department #1 | ACTIVE_NOT_RECRUITING | Kyiv | Ukraine | Details | ||
| Kyiv Regional Oncology Center, Department of Hematology, | COMPLETED | Kyiv | Ukraine | Details | ||
| Limited Liability Company "City Doctor" | ACTIVE_NOT_RECRUITING | Kyiv | Ukraine | Details | ||
| Institute of Blood Pathology and Transfusion Medicine, Department of Hematology | ACTIVE_NOT_RECRUITING | Lviv | Ukraine | Details | ||
| Poltava M.V. Sklifosovskyi Regional Clinical Hospital under Poltava Regional Council, Department of Hematology | ACTIVE_NOT_RECRUITING | Poltava | Ukraine | Details | ||
| Royal Hallamshire Hospital, Department of Hematology | RECRUITING | Sheffield | South Yorkshire | United Kingdom | Details | |
| Beatson West of Scotland Cancer Centre | RECRUITING | Glasgow | G12 0ZD | United Kingdom | Details | |
| Gloucestershire Royal Hospital | RECRUITING | Gloucester | United Kingdom | Details | ||
| Barts Health NHS Trust - The Royal London Hospital | RECRUITING | London | E1 2ES | United Kingdom | Details | |
| Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital | RECRUITING | London | United Kingdom | Details | ||
| Imperial College Healthcare NHS Trust - Hammersmith Hospital | RECRUITING | London | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | WITHDRAWN | Manchester | United Kingdom | Details | ||
| Oxford University Hospitals NHS Trust - Churchill Hospital | RECRUITING | Oxford | United Kingdom | Details |