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| NCT ID | NCT03213704 |
| Title | Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) |
| Recruitment | Recruiting |
| Gender | |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | National Cancer Institute (NCI) |
| Indications | |
| Therapies | |
| Age Groups: | adult | child |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Children's Hospital of Alabama | Recruiting | Birmingham | Alabama | 35233 | United States | Details |
| Providence Alaska Medical Center | Recruiting | Anchorage | Alaska | 99508 | United States | Details |
| Banner Children's at Desert | Recruiting | Mesa | Arizona | 85202 | United States | Details |
| Banner University Medical Center - Tucson | Recruiting | Tucson | Arizona | 85719 | United States | Details |
| Arkansas Children's Hospital | Recruiting | Little Rock | Arkansas | 72202-3591 | United States | Details |
| Kaiser Permanente Downey Medical Center | Recruiting | Downey | California | 90242 | United States | Details |
| Loma Linda University Medical Center | Recruiting | Loma Linda | California | 92354 | United States | Details |
| Miller Children's and Women's Hospital Long Beach | Recruiting | Long Beach | California | 90806 | United States | Details |
| Children's Hospital Los Angeles | Recruiting | Los Angeles | California | 90027 | United States | Details |
| Valley Children's Hospital | Recruiting | Madera | California | 93636 | United States | Details |
| UCSF Benioff Children's Hospital Oakland | Recruiting | Oakland | California | 94609 | United States | Details |
| Kaiser Permanente-Oakland | Recruiting | Oakland | California | 94611 | United States | Details |
| University of California Davis Comprehensive Cancer Center | Recruiting | Sacramento | California | 95817 | United States | Details |
| UCSF Medical Center-Mission Bay | Recruiting | San Francisco | California | 94158 | United States | Details |
| Children's Hospital Colorado | Recruiting | Aurora | Colorado | 80045 | United States | Details |
| Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center | Recruiting | Denver | Colorado | 80218 | United States | Details |
| Yale University | Recruiting | New Haven | Connecticut | 06520 | United States | Details |
| Alfred I duPont Hospital for Children | Recruiting | Wilmington | Delaware | 19803 | United States | Details |
| Children's National Medical Center | Recruiting | Washington | District of Columbia | 20010 | United States | Details |
| University of Florida Health Science Center - Gainesville | Recruiting | Gainesville | Florida | 32610 | United States | Details |
| Nemours Children's Clinic-Jacksonville | Recruiting | Jacksonville | Florida | 32207 | United States | Details |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Recruiting | Miami | Florida | 33136 | United States | Details |
| Nicklaus Children's Hospital | Recruiting | Miami | Florida | 33155 | United States | Details |
| AdventHealth Orlando | Recruiting | Orlando | Florida | 32803 | United States | Details |
| Arnold Palmer Hospital for Children | Recruiting | Orlando | Florida | 32806 | United States | Details |
| Nemours Children's Hospital | Recruiting | Orlando | Florida | 32827 | United States | Details |
| Nemours Children's Clinic - Pensacola | Active, not recruiting | Pensacola | Florida | 32504 | United States | Details |
| Johns Hopkins All Children's Hospital | Suspended | Saint Petersburg | Florida | 33701 | United States | Details |
| Saint Joseph's Hospital/Children's Hospital-Tampa | Active, not recruiting | Tampa | Florida | 33607 | United States | Details |
| Saint Mary's Hospital | Recruiting | West Palm Beach | Florida | 33407 | United States | Details |
| Children's Healthcare of Atlanta - Egleston | Recruiting | Atlanta | Georgia | 30322 | United States | Details |
| Saint Luke's Cancer Institute - Boise | Recruiting | Boise | Idaho | 83712 | United States | Details |
| Lurie Children's Hospital-Chicago | Recruiting | Chicago | Illinois | 60611 | United States | Details |
| University of Chicago Comprehensive Cancer Center | Recruiting | Chicago | Illinois | 60637 | United States | Details |
| Saint Jude Midwest Affiliate | Recruiting | Peoria | Illinois | 61637 | United States | Details |
| Southern Illinois University School of Medicine | Recruiting | Springfield | Illinois | 62702 | United States | Details |
| Riley Hospital for Children | Recruiting | Indianapolis | Indiana | 46202 | United States | Details |
| Ascension Saint Vincent Indianapolis Hospital | Recruiting | Indianapolis | Indiana | 46260 | United States | Details |
| Blank Children's Hospital | Recruiting | Des Moines | Iowa | 50309 | United States | Details |
| University of Iowa/Holden Comprehensive Cancer Center | Recruiting | Iowa City | Iowa | 52242 | United States | Details |
| Norton Children's Hospital | Recruiting | Louisville | Kentucky | 40202 | United States | Details |
| Children's Hospital New Orleans | Recruiting | New Orleans | Louisiana | 70118 | United States | Details |
| Ochsner Medical Center Jefferson | Recruiting | New Orleans | Louisiana | 70121 | United States | Details |
| Eastern Maine Medical Center | Recruiting | Bangor | Maine | 04401 | United States | Details |
| Sinai Hospital of Baltimore | Recruiting | Baltimore | Maryland | 21215 | United States | Details |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Recruiting | Baltimore | Maryland | 21287 | United States | Details |
| C S Mott Children's Hospital | Recruiting | Ann Arbor | Michigan | 48109 | United States | Details |
| Michigan State University Clinical Center | Recruiting | East Lansing | Michigan | 48824-7016 | United States | Details |
| Helen DeVos Children's Hospital at Spectrum Health | Recruiting | Grand Rapids | Michigan | 49503 | United States | Details |
| Bronson Methodist Hospital | Recruiting | Kalamazoo | Michigan | 49007 | United States | Details |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Recruiting | Minneapolis | Minnesota | 55404 | United States | Details |
| University of Minnesota/Masonic Cancer Center | Recruiting | Minneapolis | Minnesota | 55455 | United States | Details |
| Mayo Clinic in Rochester | Recruiting | Rochester | Minnesota | 55905 | United States | Details |
| University of Mississippi Medical Center | Recruiting | Jackson | Mississippi | 39216 | United States | Details |
| Children's Mercy Hospitals and Clinics | Recruiting | Kansas City | Missouri | 64108 | United States | Details |
| Cardinal Glennon Children's Medical Center | Recruiting | Saint Louis | Missouri | 63104 | United States | Details |
| Washington University School of Medicine | Recruiting | Saint Louis | Missouri | 63110 | United States | Details |
| Mercy Hospital Saint Louis | Recruiting | Saint Louis | Missouri | 63141 | United States | Details |
| Children's Hospital and Medical Center of Omaha | Recruiting | Omaha | Nebraska | 68114 | United States | Details |
| University of Nebraska Medical Center | Recruiting | Omaha | Nebraska | 68198 | United States | Details |
| University Medical Center of Southern Nevada | Suspended | Las Vegas | Nevada | 89102 | United States | Details |
| Sunrise Hospital and Medical Center | Suspended | Las Vegas | Nevada | 89109 | United States | Details |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Suspended | Las Vegas | Nevada | 89135 | United States | Details |
| Summerlin Hospital Medical Center | Suspended | Las Vegas | Nevada | 89144 | United States | Details |
| Hackensack University Medical Center | Recruiting | Hackensack | New Jersey | 07601 | United States | Details |
| Morristown Medical Center | Recruiting | Morristown | New Jersey | 07960 | United States | Details |
| Saint Peter's University Hospital | Recruiting | New Brunswick | New Jersey | 08901 | United States | Details |
| Albany Medical Center | Recruiting | Albany | New York | 12208 | United States | Details |
| Montefiore Medical Center - Moses Campus | Recruiting | Bronx | New York | 10467 | United States | Details |
| Roswell Park Cancer Institute | Recruiting | Buffalo | New York | 14263 | United States | Details |
| The Steven and Alexandra Cohen Children's Medical Center of New York | Recruiting | New Hyde Park | New York | 11040 | United States | Details |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | Recruiting | New York | New York | 10032 | United States | Details |
| Memorial Sloan Kettering Cancer Center | Recruiting | New York | New York | 10065 | United States | Details |
| NYP/Weill Cornell Medical Center | Recruiting | New York | New York | 10065 | United States | Details |
| University of Rochester | Recruiting | Rochester | New York | 14642 | United States | Details |
| Stony Brook University Medical Center | Recruiting | Stony Brook | New York | 11794 | United States | Details |
| State University of New York Upstate Medical University | Recruiting | Syracuse | New York | 13210 | United States | Details |
| New York Medical College | Recruiting | Valhalla | New York | 10595 | United States | Details |
| Mission Hospital | Recruiting | Asheville | North Carolina | 28801 | United States | Details |
| Carolinas Medical Center/Levine Cancer Institute | Recruiting | Charlotte | North Carolina | 28203 | United States | Details |
| Novant Health Presbyterian Medical Center | Recruiting | Charlotte | North Carolina | 28204 | United States | Details |
| Duke University Medical Center | Recruiting | Durham | North Carolina | 27710 | United States | Details |
| Sanford Broadway Medical Center | Recruiting | Fargo | North Dakota | 58122 | United States | Details |
| Cincinnati Children's Hospital Medical Center | Recruiting | Cincinnati | Ohio | 45229 | United States | Details |
| Rainbow Babies and Childrens Hospital | Recruiting | Cleveland | Ohio | 44106 | United States | Details |
| Cleveland Clinic Foundation | Suspended | Cleveland | Ohio | 44195 | United States | Details |
| Nationwide Children's Hospital | Recruiting | Columbus | Ohio | 43205 | United States | Details |
| Dayton Children's Hospital | Recruiting | Dayton | Ohio | 45404 | United States | Details |
| ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital | Recruiting | Toledo | Ohio | 43606 | United States | Details |
| University of Oklahoma Health Sciences Center | Recruiting | Oklahoma City | Oklahoma | 73104 | United States | Details |
| Legacy Emanuel Children's Hospital | Recruiting | Portland | Oregon | 97227 | United States | Details |
| Oregon Health and Science University | Recruiting | Portland | Oregon | 97239 | United States | Details |
| Geisinger Medical Center | Recruiting | Danville | Pennsylvania | 17822 | United States | Details |
| Children's Hospital of Philadelphia | Recruiting | Philadelphia | Pennsylvania | 19104 | United States | Details |
| Children's Hospital of Pittsburgh of UPMC | Recruiting | Pittsburgh | Pennsylvania | 15224 | United States | Details |
| Prisma Health Richland Hospital | Recruiting | Columbia | South Carolina | 29203 | United States | Details |
| BI-LO Charities Children's Cancer Center | Recruiting | Greenville | South Carolina | 29605 | United States | Details |
| Sanford USD Medical Center - Sioux Falls | Recruiting | Sioux Falls | South Dakota | 57117-5134 | United States | Details |
| East Tennessee Childrens Hospital | Recruiting | Knoxville | Tennessee | 37916 | United States | Details |
| Saint Jude Children's Research Hospital | Recruiting | Memphis | Tennessee | 38105 | United States | Details |
| The Children's Hospital at TriStar Centennial | Recruiting | Nashville | Tennessee | 37203 | United States | Details |
| Vanderbilt University/Ingram Cancer Center | Recruiting | Nashville | Tennessee | 37232 | United States | Details |
| Dell Children's Medical Center of Central Texas | Recruiting | Austin | Texas | 78723 | United States | Details |
| Driscoll Children's Hospital | Recruiting | Corpus Christi | Texas | 78411 | United States | Details |
| Medical City Dallas Hospital | Recruiting | Dallas | Texas | 75230 | United States | Details |
| UT Southwestern/Simmons Cancer Center-Dallas | Recruiting | Dallas | Texas | 75390 | United States | Details |
| Cook Children's Medical Center | Recruiting | Fort Worth | Texas | 76104 | United States | Details |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Recruiting | Houston | Texas | 77030 | United States | Details |
| M D Anderson Cancer Center | Recruiting | Houston | Texas | 77030 | United States | Details |
| Children's Hospital of San Antonio | Recruiting | San Antonio | Texas | 78207 | United States | Details |
| Methodist Children's Hospital of South Texas | Recruiting | San Antonio | Texas | 78229 | United States | Details |
| University of Texas Health Science Center at San Antonio | Recruiting | San Antonio | Texas | 78229 | United States | Details |
| Scott and White Memorial Hospital | Recruiting | Temple | Texas | 76508 | United States | Details |
| Primary Children's Hospital | Recruiting | Salt Lake City | Utah | 84113 | United States | Details |
| Children's Hospital of The King's Daughters | Recruiting | Norfolk | Virginia | 23507 | United States | Details |
| Virginia Commonwealth University/Massey Cancer Center | Recruiting | Richmond | Virginia | 23298 | United States | Details |
| Seattle Children's Hospital | Recruiting | Seattle | Washington | 98105 | United States | Details |
| Providence Sacred Heart Medical Center and Children's Hospital | Recruiting | Spokane | Washington | 99204 | United States | Details |
| Madigan Army Medical Center | Recruiting | Tacoma | Washington | 98431 | United States | Details |
| West Virginia University Healthcare | Active, not recruiting | Morgantown | West Virginia | 26506 | United States | Details |
| University of Wisconsin Carbone Cancer Center | Recruiting | Madison | Wisconsin | 53792 | United States | Details |
| Marshfield Medical Center-Marshfield | Recruiting | Marshfield | Wisconsin | 54449 | United States | Details |
| Children's Hospital of Wisconsin | Recruiting | Milwaukee | Wisconsin | 53226 | United States | Details |
| San Jorge Children's Hospital | Active, not recruiting | San Juan | 00912 | Puerto Rico | Details | |
| University Pediatric Hospital | Recruiting | San Juan | 00926 | Puerto Rico | Details |