Disease Detail

ID JAX:10000003
Name Advanced Solid Tumor
Definition “An abnormal mass of tissue that usually does not contain cysts or liquid areas. Different types of solid tumors are named for the type of cells that form them. Examples of solid tumors are sarcomas, carcinomas, and lymphomas). ”
Source The Jackson Laboratory (a custom term added that does not corresond to an existing term in the disease ontology)
Alt Ids
Path Advanced Solid Tumor

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
EGFR positive Pelitinib Advanced Solid Tumor no benefit detail...
Unknown unknown Ganetespib Advanced Solid Tumor not applicable detail...
Unknown unknown BGT226 Advanced Solid Tumor not applicable detail...
PIK3CA mutant CUDC-907 Advanced Solid Tumor sensitive detail...
PIK3CA wild-type PX-866 Advanced Solid Tumor sensitive detail...
Unknown unknown XL147 Advanced Solid Tumor not applicable detail...
PIK3CA mutant PX-866 Advanced Solid Tumor sensitive detail...
TP53 mutant Bevacizumab Advanced Solid Tumor sensitive detail...
PDGFRA V561D Imatinib Advanced Solid Tumor sensitive detail...
Unknown unknown AC480 Advanced Solid Tumor not applicable detail...
Unknown unknown AT9283 Advanced Solid Tumor not applicable detail...
Unknown unknown BMS-690514 Advanced Solid Tumor not applicable detail...
Unknown unknown Carboxyamidotriazole Orotate + Paclitaxel Advanced Solid Tumor not applicable detail...
Unknown unknown Danusertib Advanced Solid Tumor not applicable detail...
EGFR positive EGFRBi-armed autologous activated T cells Advanced Solid Tumor sensitive detail...
Unknown unknown Famitinib Advanced Solid Tumor not applicable detail...
FGFR2 act mut Debio 1347 Advanced Solid Tumor sensitive detail...
PIK3CA act mut Taselisib Advanced Solid Tumor conflicting detail...
Unknown unknown Ipatasertib Advanced Solid Tumor not applicable detail...
Unknown unknown GDC-0349 Advanced Solid Tumor not applicable detail...
Unknown unknown Fluorouracil + Methylnaltrexone Advanced Solid Tumor not applicable detail...
PIK3CA mutant M2698 Advanced Solid Tumor sensitive detail...
TP53 positive MVAp53 Advanced Solid Tumor sensitive detail...
Unknown unknown Neratinib + Temsirolimus Advanced Solid Tumor not applicable detail...
Unknown unknown Carboplatin + Paclitaxel + Pazopanib Advanced Solid Tumor not applicable detail...
BRAF V600E PLX8394 Advanced Solid Tumor sensitive detail...
Unknown unknown PR610 Advanced Solid Tumor not applicable detail...
Unknown unknown Rigosertib Advanced Solid Tumor not applicable detail...
Unknown unknown Alisertib Advanced Solid Tumor not applicable detail...
Unknown unknown Fluorouracil + Sorafenib Advanced Solid Tumor not applicable detail...
Unknown unknown Cabozantinib Advanced Solid Tumor not applicable detail...
Unknown unknown Apatinib Advanced Solid Tumor not applicable detail...
Unknown unknown Pazopanib Advanced Solid Tumor not applicable detail...
MET R988C Crizotinib Advanced Solid Tumor sensitive detail...
Unknown unknown MRX34 Advanced Solid Tumor not applicable detail...
Unknown unknown Reolysin Advanced Solid Tumor not applicable detail...
Unknown unknown Sirolimus Advanced Solid Tumor not applicable detail...
Unknown unknown PX-866 + Sorafenib Advanced Solid Tumor not applicable detail...
Unknown unknown M2698 Advanced Solid Tumor not applicable detail...
Unknown unknown VS-5584 Advanced Solid Tumor not applicable detail...
Unknown unknown Miransertib Advanced Solid Tumor not applicable detail...
BRAF L597R Trametinib Advanced Solid Tumor sensitive detail...
BRAF L597R Vemurafenib Advanced Solid Tumor sensitive detail...
BRAF L597S Vemurafenib Advanced Solid Tumor sensitive detail...
BRAF L597S Trametinib Advanced Solid Tumor sensitive detail...
BRAF K601E Trametinib Advanced Solid Tumor sensitive detail...
BRAF K601E Vemurafenib Advanced Solid Tumor conflicting detail...
BRAF mutant Dabrafenib Advanced Solid Tumor sensitive detail...
Unknown unknown Binimetinib Advanced Solid Tumor not applicable detail...
EGFR S768_D770dup Afatinib Advanced Solid Tumor resistant detail...
PDGFRA D842V Imatinib Advanced Solid Tumor resistant detail...
TP53 wild-type Pazopanib + Vorinostat Advanced Solid Tumor decreased response detail...
Unknown unknown RXDX-105 Advanced Solid Tumor not applicable detail...
ERBB2 amp Afatinib Advanced Solid Tumor sensitive detail...
RET mutant Ponatinib Advanced Solid Tumor sensitive detail...
KDR positive Anti-VEGFR2 CAR CD8 lymphocytes Advanced Solid Tumor predicted - sensitive detail...
MET positive Merestinib Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Glesatinib Advanced Solid Tumor not applicable detail...
KDR act mut Lucitanib Advanced Solid Tumor predicted - sensitive detail...
BRAF act mut Binimetinib + Encorafenib Advanced Solid Tumor sensitive detail...
BRAF act mut PLX8394 Advanced Solid Tumor sensitive detail...
FGFR3 R248C R3Mab Advanced Solid Tumor sensitive detail...
FGFR3 S249C R3Mab Advanced Solid Tumor sensitive detail...
FGFR3 G372C R3Mab Advanced Solid Tumor sensitive detail...
FGFR3 Y375C R3Mab Advanced Solid Tumor sensitive detail...
FGFR3 K652E R3Mab Advanced Solid Tumor sensitive detail...
Unknown unknown SGI-1027 Advanced Solid Tumor not applicable detail...
STK11 wild-type Metformin Advanced Solid Tumor sensitive detail...
STK11 loss Metformin Advanced Solid Tumor no benefit detail...
FGFR3 mutant BGJ398 Advanced Solid Tumor sensitive detail...
Unknown unknown Erdafitinib Advanced Solid Tumor not applicable detail...
TP53 loss Adavosertib Advanced Solid Tumor sensitive detail...
Unknown unknown Paclitaxel + TAS-119 Advanced Solid Tumor not applicable detail...
SMO D473H Taladegib Advanced Solid Tumor sensitive detail...
EGFR positive S-222611 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Selumetinib Advanced Solid Tumor not applicable detail...
Unknown unknown Talazoparib Advanced Solid Tumor not applicable detail...
PTEN negative Talazoparib Advanced Solid Tumor sensitive detail...
PIK3CA mutant XL147 Advanced Solid Tumor sensitive detail...
RET G691S Dovitinib Advanced Solid Tumor sensitive detail...
ERBB2 positive S-222611 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown JNJ-26483327 Advanced Solid Tumor not applicable detail...
Unknown unknown Anlotinib Advanced Solid Tumor not applicable detail...
Unknown unknown Docetaxel + TAS-119 Advanced Solid Tumor not applicable detail...
Unknown unknown Bevacizumab + Telatinib Advanced Solid Tumor not applicable detail...
FGFR1 act mut Debio 1347 Advanced Solid Tumor sensitive detail...
FGFR3 act mut Debio 1347 Advanced Solid Tumor sensitive detail...
Unknown unknown AMG 900 Advanced Solid Tumor not applicable detail...
KDR wild-type Ramucirumab Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown BI-847325 Advanced Solid Tumor not applicable detail...
Unknown unknown Varlitinib Advanced Solid Tumor not applicable detail...
AKT1 E17K Capivasertib Advanced Solid Tumor sensitive detail...
Unknown unknown Gedatolisib Advanced Solid Tumor not applicable detail...
PIK3CA act mut BAY1125976 Advanced Solid Tumor sensitive detail...
PTEN loss BAY1125976 Advanced Solid Tumor sensitive detail...
Unknown unknown Sapanisertib Advanced Solid Tumor not applicable detail...
Unknown unknown PD-0325901 Advanced Solid Tumor not applicable detail...
Unknown unknown Refametinib Advanced Solid Tumor not applicable detail...
PIK3CA act mut Everolimus Advanced Solid Tumor sensitive detail...
PIK3CA E542K Sirolimus Advanced Solid Tumor sensitive detail...
Unknown unknown CC-223 Advanced Solid Tumor not applicable detail...
Unknown unknown Cobimetinib + Ipatasertib Advanced Solid Tumor not applicable detail...
Unknown unknown MK2206 Advanced Solid Tumor not applicable detail...
PIK3CA act mut Metformin Advanced Solid Tumor sensitive detail...
EGFR L858R AV-412 Advanced Solid Tumor sensitive detail...
EGFR T790M AV-412 Advanced Solid Tumor sensitive detail...
Unknown unknown Cobimetinib Advanced Solid Tumor not applicable detail...
PIK3CA E545K Sirolimus Advanced Solid Tumor sensitive detail...
PIK3CA E545K Alpelisib Advanced Solid Tumor sensitive detail...
PIK3CA mutant CC-223 Advanced Solid Tumor sensitive detail...
PIK3CA act mut Ipatasertib + Paclitaxel Advanced Solid Tumor sensitive detail...
PIK3CA act mut Afuresertib Advanced Solid Tumor sensitive detail...
KDR act mut Sorafenib Advanced Solid Tumor sensitive detail...
Unknown unknown Bardoxolone methyl Advanced Solid Tumor not applicable detail...
KDR act mut Sunitinib Advanced Solid Tumor sensitive detail...
KDR A1065T Sunitinib Advanced Solid Tumor sensitive detail...
KDR D717V Sunitinib Advanced Solid Tumor sensitive detail...
Unknown unknown JIB-04 Advanced Solid Tumor not applicable detail...
Unknown unknown AZD7762 + Gemcitabine Advanced Solid Tumor no benefit detail...
Unknown unknown Alpelisib Advanced Solid Tumor not applicable detail...
Unknown unknown Merestinib Advanced Solid Tumor not applicable detail...
MET amp Capmatinib Advanced Solid Tumor predicted - sensitive detail...
JAK3 V722I Tofacitinib Advanced Solid Tumor sensitive detail...
Unknown unknown Tivantinib Advanced Solid Tumor not applicable detail...
MET amp Emibetuzumab Advanced Solid Tumor sensitive detail...
Unknown unknown ME-344 Advanced Solid Tumor not applicable detail...
Unknown unknown Tivozanib Advanced Solid Tumor not applicable detail...
PIK3CA C420R Sirolimus Advanced Solid Tumor sensitive detail...
Unknown unknown Buparlisib Advanced Solid Tumor not applicable detail...
PIK3CA mutant Alpelisib Advanced Solid Tumor sensitive detail...
PIK3CA mutant Carboxyamidotriazole Orotate Advanced Solid Tumor sensitive detail...
PIK3CA mutant MLN1117 Advanced Solid Tumor sensitive detail...
PIK3CA mutant VS-5584 Advanced Solid Tumor sensitive detail...
RB1 positive Ribociclib Advanced Solid Tumor predicted - sensitive detail...
HRAS G12V Cetuximab Advanced Solid Tumor resistant detail...
HRAS G12V Panitumumab Advanced Solid Tumor resistant detail...
MET act mut Emibetuzumab Advanced Solid Tumor sensitive detail...
MET amp ABT-700 Advanced Solid Tumor sensitive detail...
Unknown unknown Sapitinib Advanced Solid Tumor not applicable detail...
Unknown unknown Bosutinib Advanced Solid Tumor not applicable detail...
Unknown unknown PF-562271 Advanced Solid Tumor not applicable detail...
Unknown unknown Poziotinib Advanced Solid Tumor not applicable detail...
Unknown unknown PF-03446962 Advanced Solid Tumor not applicable detail...
FLT3 D835Y Midostaurin Advanced Solid Tumor sensitive detail...
Unknown unknown Midostaurin Advanced Solid Tumor not applicable detail...
Unknown unknown AMG208 Advanced Solid Tumor not applicable detail...
Unknown unknown Amuvatinib + Carboplatin + Paclitaxel Advanced Solid Tumor not applicable detail...
Unknown unknown Erlotinib + Ficlatuzumab Advanced Solid Tumor not applicable detail...
RET S891A Sorafenib Advanced Solid Tumor sensitive detail...
RET M918T Sorafenib Advanced Solid Tumor sensitive detail...
RET C634R Sorafenib Advanced Solid Tumor sensitive detail...
MET amp SAR125844 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Axitinib + Bevacizumab Advanced Solid Tumor not applicable detail...
EGFR S768I Erlotinib Advanced Solid Tumor decreased response detail...
BRAF mutant Obatoclax Advanced Solid Tumor sensitive detail...
NRAS mutant Obatoclax Advanced Solid Tumor sensitive detail...
PDGFRA G853D Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA G853D Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA I843del Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA N659K Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA N659K Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA P577S Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA P577S Crenolanib Advanced Solid Tumor sensitive detail...
Unknown unknown Lenvatinib Advanced Solid Tumor not applicable detail...
EGFR L747_P753delinsS Gefitinib Advanced Solid Tumor sensitive detail...
EGFR L747_P753delinsS AEE788 Advanced Solid Tumor sensitive detail...
PDGFRA R841K Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA R841K Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA V658A Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA H845Y Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA H845Y Imatinib Advanced Solid Tumor sensitive detail...
RET C634R Ponatinib Advanced Solid Tumor sensitive detail...
RET V804L Ponatinib Advanced Solid Tumor sensitive detail...
RET V804M Ponatinib Advanced Solid Tumor sensitive detail...
Unknown unknown XL999 Advanced Solid Tumor not applicable detail...
ERBB2 H878Y AEE788 Advanced Solid Tumor sensitive detail...
ERBB2 H878Y Lapatinib Advanced Solid Tumor sensitive detail...
ERBB2 L755P AEE788 Advanced Solid Tumor resistant detail...
ERBB2 L755P Lapatinib Advanced Solid Tumor resistant detail...
ERBB2 L755S AEE788 Advanced Solid Tumor resistant detail...
ERBB2 L755S Lapatinib Advanced Solid Tumor resistant detail...
ERBB2 T798M AEE788 Advanced Solid Tumor resistant detail...
ERBB2 V777L AEE788 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171T Ceritinib Advanced Solid Tumor sensitive detail...
Unknown unknown Gemcitabine + Trametinib Advanced Solid Tumor not applicable detail...
Unknown unknown Nintedanib Advanced Solid Tumor not applicable detail...
PIK3CA mutant Sapanisertib Advanced Solid Tumor sensitive detail...
Unknown unknown A-1331852 Advanced Solid Tumor not applicable detail...
EML4-ALK ALK C1156Y Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK C1156Y Ensartinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1196M Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M Ensartinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK S1206Y Ceritinib Advanced Solid Tumor sensitive detail...
EGFR E734Q Erlotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1152R Crizotinib Advanced Solid Tumor resistant detail...
SMO W535L Vismodegib Advanced Solid Tumor resistant detail...
SMO V321M Vismodegib Advanced Solid Tumor resistant detail...
RET V804M Sorafenib Advanced Solid Tumor sensitive detail...
SMO F460L Vismodegib Advanced Solid Tumor resistant detail...
SMO L412F Vismodegib Advanced Solid Tumor resistant detail...
EGFR D761Y EGFR L858R Gefitinib Advanced Solid Tumor decreased response detail...
EGFR L858R EGFR T854A Erlotinib Advanced Solid Tumor decreased response detail...
Unknown unknown MM-151 Advanced Solid Tumor not applicable detail...
Unknown unknown Panitumumab Advanced Solid Tumor not applicable detail...
Unknown unknown Paclitaxel + Pazopanib Advanced Solid Tumor not applicable detail...
Unknown unknown Aflibercept Advanced Solid Tumor not applicable detail...
Unknown unknown Axitinib Advanced Solid Tumor not applicable detail...
Unknown unknown Regorafenib Advanced Solid Tumor not applicable detail...
Unknown unknown Onalespib Advanced Solid Tumor not applicable detail...
FLT3 Y572C Midostaurin Advanced Solid Tumor sensitive detail...
FLT3 S451F Midostaurin Advanced Solid Tumor decreased response detail...
FLT3 V592G Midostaurin Advanced Solid Tumor sensitive detail...
FLT3 R834Q Midostaurin Advanced Solid Tumor sensitive detail...
FLT3 R834Q PD98059 Advanced Solid Tumor sensitive detail...
PIK3CA M1043V Sirolimus Advanced Solid Tumor sensitive detail...
PIK3CA mutant BAY1082439 Advanced Solid Tumor sensitive detail...
Unknown unknown Birabresib Advanced Solid Tumor not applicable detail...
Unknown unknown ONC201 Advanced Solid Tumor not applicable detail...
FLT3 exon 14 ins FLT3 D839G Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 Y842C Pexidartinib Advanced Solid Tumor resistant detail...
Unknown unknown AZD8186 Advanced Solid Tumor not applicable detail...
Unknown unknown CLR457 Advanced Solid Tumor not applicable detail...
FGFR3 amp Ponatinib Advanced Solid Tumor predicted - sensitive detail...
FGFR3 amp BGJ398 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown MEDI0639 Advanced Solid Tumor not applicable detail...
Unknown unknown Brontictuzumab Advanced Solid Tumor not applicable detail...
Unknown unknown Vorolanib Advanced Solid Tumor not applicable detail...
Unknown unknown SAR245409 Advanced Solid Tumor not applicable detail...
Unknown unknown LY3023414 Advanced Solid Tumor not applicable detail...
KIT V560D Sorafenib Advanced Solid Tumor sensitive detail...
KIT V560D Dasatinib Advanced Solid Tumor sensitive detail...
Unknown unknown MGCD516 Advanced Solid Tumor not applicable detail...
KIT V560G Nilotinib Advanced Solid Tumor sensitive detail...
EGFR amp MM-151 Advanced Solid Tumor predicted - sensitive detail...
EGFR exon 20 ins Rociletinib Advanced Solid Tumor resistant detail...
EGFR exon 20 ins Dacomitinib Advanced Solid Tumor resistant detail...
EGFR exon 20 ins Osimertinib Advanced Solid Tumor resistant detail...
FGFR2 N550K Dovitinib Advanced Solid Tumor resistant detail...
FGFR2 N550S Dovitinib Advanced Solid Tumor decreased response detail...
FGFR2 N550H Dovitinib Advanced Solid Tumor decreased response detail...
FGFR2 V565I Dovitinib Advanced Solid Tumor resistant detail...
FGFR2 E566G Dovitinib Advanced Solid Tumor resistant detail...
FGFR2 L618M Dovitinib Advanced Solid Tumor decreased response detail...
FGFR2 K660E Dovitinib Advanced Solid Tumor resistant detail...
FGFR2 I548V Dovitinib Advanced Solid Tumor decreased response detail...
FGFR2 M538I Dovitinib Advanced Solid Tumor decreased response detail...
FGFR2 M536I Dovitinib Advanced Solid Tumor decreased response detail...
FGFR2 N550H PD173074 Advanced Solid Tumor resistant detail...
FGFR2 E566G PD173074 Advanced Solid Tumor resistant detail...
FGFR2 M536I PD173074 Advanced Solid Tumor decreased response detail...
FGFR2 M538I PD173074 Advanced Solid Tumor decreased response detail...
FGFR2 I548V PD173074 Advanced Solid Tumor decreased response detail...
FGFR2 N550S PD173074 Advanced Solid Tumor decreased response detail...
FGFR2 L618M PD173074 Advanced Solid Tumor decreased response detail...
FGFR2 V565I Ponatinib Advanced Solid Tumor resistant detail...
FGFR2 M538I Ponatinib Advanced Solid Tumor decreased response detail...
FGFR2 K660E Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 M536I Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 I548V Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 N550H Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 N550K Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 N550S Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 E566G Ponatinib Advanced Solid Tumor sensitive detail...
MET N375S SU11274 Advanced Solid Tumor decreased response detail...
Unknown unknown Icrucumab Advanced Solid Tumor not applicable detail...
Unknown unknown REGN421 Advanced Solid Tumor not applicable detail...
FGFR2 S267_D273dup BGJ398 Advanced Solid Tumor sensitive detail...
FGFR2 W290_I291delinsC BGJ398 Advanced Solid Tumor sensitive detail...
FGFR2 - TACC3 BGJ398 Advanced Solid Tumor sensitive detail...
FGFR2 S267_D273dup Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 W290_I291delinsC Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 - TACC3 Ponatinib Advanced Solid Tumor sensitive detail...
Unknown unknown AZD8330 Advanced Solid Tumor not applicable detail...
Unknown unknown PF-04691502 Advanced Solid Tumor not applicable detail...
Unknown unknown DCBCI0901 Advanced Solid Tumor not applicable detail...
Unknown unknown RO5126766 Advanced Solid Tumor not applicable detail...
Unknown unknown DS-7423 Advanced Solid Tumor not applicable detail...
Unknown unknown SAR260301 Advanced Solid Tumor no benefit detail...
Unknown unknown SF1126 Advanced Solid Tumor not applicable detail...
PIK3CA mutant A-443654 Advanced Solid Tumor sensitive detail...
PIK3CA E545K A66 Advanced Solid Tumor resistant detail...
PIK3CA H1047R A66 Advanced Solid Tumor sensitive detail...
Unknown unknown ABTL0812 Advanced Solid Tumor not applicable detail...
Unknown unknown LY2780301 Advanced Solid Tumor not applicable detail...
PIK3CA mutant AT-7867 Advanced Solid Tumor sensitive detail...
Unknown unknown Perifosine Advanced Solid Tumor not applicable detail...
Unknown unknown PQR309 Advanced Solid Tumor not applicable detail...
Unknown unknown CH5132799 Advanced Solid Tumor not applicable detail...
Unknown unknown DS-3078a Advanced Solid Tumor not applicable detail...
PIK3CA mutant Taselisib Advanced Solid Tumor sensitive detail...
Unknown unknown GSK2126458 Advanced Solid Tumor not applicable detail...
Unknown unknown Trametinib + Uprosertib Advanced Solid Tumor not applicable detail...
ERBB2 S310F Lapatinib Advanced Solid Tumor sensitive detail...
ERBB2 act mut AEE788 Advanced Solid Tumor sensitive detail...
AKT1 act mut Triciribine Advanced Solid Tumor no benefit detail...
Unknown unknown ZSTK474 Advanced Solid Tumor not applicable detail...
ERBB2 G776_V777insYVMA Canertinib Advanced Solid Tumor sensitive detail...
ERBB2 positive AC480 Advanced Solid Tumor predicted - sensitive detail...
ERBB2 S310F Neratinib Advanced Solid Tumor sensitive detail...
Unknown unknown Roniciclib Advanced Solid Tumor not applicable detail...
Unknown unknown AT7519 Advanced Solid Tumor not applicable detail...
Unknown unknown Seliciclib Advanced Solid Tumor not applicable detail...
Unknown unknown P276-00 Advanced Solid Tumor not applicable detail...
EML4-ALK ALK C1156Y Alectinib Advanced Solid Tumor sensitive detail...
NOTCH1 A1707T MRK-003 Advanced Solid Tumor sensitive detail...
EGFR D761Y EGFR L858R Neratinib Advanced Solid Tumor decreased response detail...
EGFR L858R EGFR T790M Neratinib Advanced Solid Tumor decreased response detail...
EGFR L858R Neratinib Advanced Solid Tumor sensitive detail...
EGFR L858R EKI-285 Advanced Solid Tumor sensitive detail...
EGFR D761Y EGFR L858R EKI-285 Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR T790M EKI-285 Advanced Solid Tumor decreased response detail...
Unknown unknown AMG 337 Advanced Solid Tumor not applicable detail...
ERBB2 T798M Lapatinib Advanced Solid Tumor resistant detail...
ERBB2 T798M EKI-285 Advanced Solid Tumor sensitive detail...
ERBB2 T798M WZ4002 Advanced Solid Tumor sensitive detail...
ERBB2 L755P EKI-285 Advanced Solid Tumor sensitive detail...
ERBB2 L755P WZ4002 Advanced Solid Tumor sensitive detail...
ERBB2 L755S EKI-285 Advanced Solid Tumor sensitive detail...
ERBB2 L755S WZ4002 Advanced Solid Tumor sensitive detail...
ERBB2 N857S Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 T862A Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 V773A Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 V773A AEE788 Advanced Solid Tumor sensitive detail...
ERBB2 T862A AEE788 Advanced Solid Tumor sensitive detail...
ERBB2 N857S AEE788 Advanced Solid Tumor sensitive detail...
ERBB2 V777L Lapatinib Advanced Solid Tumor sensitive detail...
ERBB2 wild-type Lapatinib Advanced Solid Tumor sensitive detail...
ERBB2 wild-type AEE788 Advanced Solid Tumor sensitive detail...
ALK C1156Y Alectinib Advanced Solid Tumor sensitive detail...
EGFR L718Q Afatinib Advanced Solid Tumor sensitive detail...
EGFR L718Q Neratinib Advanced Solid Tumor sensitive detail...
EGFR L718Q EKI-285 Advanced Solid Tumor sensitive detail...
EGFR L844V Neratinib Advanced Solid Tumor sensitive detail...
EGFR L844V Afatinib Advanced Solid Tumor sensitive detail...
EGFR L844V EKI-285 Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR T790M EGFR L718Q Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR L718Q EGFR T790M Rociletinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR L718Q Rociletinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR L844V Rociletinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR C797S Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR L718Q Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR C797S Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR L844V Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR L844V EGFR T790M Rociletinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR T790M EGFR L844V Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR L844V Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR L844V Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR L718Q Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR L844V EGFR T790M Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR T790M EGFR L844V Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR L718Q Osimertinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR C797S Osimertinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR C797S Osimertinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR L718Q EGFR T790M Osimertinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR T790M EGFR L718Q Osimertinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR T790M EGFR Q791R Rociletinib Advanced Solid Tumor resistant detail...
EGFR L858R EGFR Q791R EGFR T790M Rociletinib Advanced Solid Tumor resistant detail...
EGFR E746_A750del EGFR T790M EGFR Q791R Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR Q791R EGFR T790M Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR L844V Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR L718Q Afatinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR L718Q Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR L844V Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR C797S Afatinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR C797S Afatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK TAE684 Advanced Solid Tumor sensitive detail...
Unknown unknown Ipafricept Advanced Solid Tumor not applicable detail...
MET amp Tepotinib Advanced Solid Tumor sensitive detail...
RET Y806C Ponatinib Advanced Solid Tumor sensitive detail...
RET A883F Ponatinib Advanced Solid Tumor sensitive detail...
RET Y791F Ponatinib Advanced Solid Tumor sensitive detail...
RET E768D Ponatinib Advanced Solid Tumor sensitive detail...
RET L790F Ponatinib Advanced Solid Tumor sensitive detail...
RET D898V Ponatinib Advanced Solid Tumor sensitive detail...
RET M918T Ponatinib Advanced Solid Tumor sensitive detail...
RET C634Y Ponatinib Advanced Solid Tumor sensitive detail...
RET E884K Ponatinib Advanced Solid Tumor sensitive detail...
RET S891A Ponatinib Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins Midostaurin Advanced Solid Tumor sensitive detail...
FLT3 wild-type Midostaurin Advanced Solid Tumor sensitive detail...
FGFR2 S252W Dovitinib Advanced Solid Tumor sensitive detail...
FGFR2 N550K PD173074 Advanced Solid Tumor resistant detail...
FGFR2 V565I PD173074 Advanced Solid Tumor resistant detail...
FGFR2 L618M Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 K660E PD173074 Advanced Solid Tumor decreased response detail...
PIK3CA mutant Bevacizumab + Pegylated liposomal-doxorubicin + Temsirolimus Advanced Solid Tumor sensitive detail...
FBXW7 inact mut Entinostat Advanced Solid Tumor sensitive detail...
FBXW7 inact mut Docetaxel Advanced Solid Tumor resistant detail...
FBXW7 inact mut Belinostat Advanced Solid Tumor sensitive detail...
FBXW7 inact mut AR-42 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK V1180L Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK I1171T Alectinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK V1180L TAE684 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171T TAE684 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK V1180L Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK V1180L Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171T Brigatinib Advanced Solid Tumor decreased response detail...
EML4-ALK ASP3026 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK V1180L ASP3026 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171T ASP3026 Advanced Solid Tumor resistant detail...
TP53 mutant Pazopanib + Vorinostat Advanced Solid Tumor sensitive detail...
RET E768D Vandetanib Advanced Solid Tumor sensitive detail...
RET L790F Vandetanib Advanced Solid Tumor sensitive detail...
RET Y791F Vandetanib Advanced Solid Tumor sensitive detail...
RET S891A Vandetanib Advanced Solid Tumor sensitive detail...
RET M918T Vandetanib Advanced Solid Tumor sensitive detail...
RET A883F Vandetanib Advanced Solid Tumor sensitive detail...
RET V804L Vandetanib Advanced Solid Tumor resistant detail...
RET V804M Vandetanib Advanced Solid Tumor resistant detail...
RET C634R Vandetanib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1196M Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174V ALK L1198F Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK S1206C Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1122V ALK L1196M Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1122V Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1196M ALK D1203N Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174V Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1198F Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK P1139S Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK Alectinib Advanced Solid Tumor sensitive detail...
NPM1-ALK Ceritinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ASP3026 Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1122V ALK L1196M Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1196M ALK D1203N Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK S1206C Crizotinib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK L1196M Crizotinib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK P1139S Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174V Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1198F Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174V ALK L1198F Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1122V Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1122V ALK L1196M Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174V ALK L1198F Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1198F Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK S1206C Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK P1139S Alectinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174V Alectinib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK L1196M Alectinib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK L1196M ALK D1203N Alectinib Advanced Solid Tumor decreased response detail...
RET C634R RET V804G Vandetanib Advanced Solid Tumor sensitive detail...
FGFR1 act mut Ponatinib Advanced Solid Tumor sensitive detail...
FGFR2 act mut Ponatinib Advanced Solid Tumor sensitive detail...
FGFR3 act mut Ponatinib Advanced Solid Tumor sensitive detail...
FGFR1 act mut Dovitinib Advanced Solid Tumor sensitive detail...
FGFR2 act mut Dovitinib Advanced Solid Tumor sensitive detail...
FGFR3 act mut Dovitinib Advanced Solid Tumor sensitive detail...
FGFR1 act mut Cediranib Advanced Solid Tumor decreased response detail...
FGFR2 act mut Cediranib Advanced Solid Tumor decreased response detail...
FGFR3 act mut Cediranib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK L1122V Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1198F Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174V ALK L1198F Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1196M ALK D1203N Ceritinib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK F1174V Ceritinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1196M Ceritinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK P1139S Ceritinib Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK S1206C Ceritinib Advanced Solid Tumor decreased response detail...
FGFR1 act mut Nintedanib Advanced Solid Tumor decreased response detail...
FGFR2 act mut Nintedanib Advanced Solid Tumor decreased response detail...
FGFR3 act mut Nintedanib Advanced Solid Tumor decreased response detail...
FGFR2 act mut Brivanib Advanced Solid Tumor decreased response detail...
FGFR1 act mut Brivanib Advanced Solid Tumor no benefit detail...
FGFR3 act mut Brivanib Advanced Solid Tumor no benefit detail...
NPM1-ALK ALK P1139S ASP3026 Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1196M ALK D1203N ASP3026 Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK L1122V ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1122V ALK L1196M ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174V ALK L1198F ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1196M ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK L1198F ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK S1206C ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174V ASP3026 Advanced Solid Tumor predicted - sensitive detail...
KIT D816V Ponatinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins Cabozantinib Advanced Solid Tumor predicted - sensitive detail...
KIT D816V Sunitinib Advanced Solid Tumor resistant detail...
KIT D816V Nilotinib Advanced Solid Tumor decreased response detail...
KIT D816V Imatinib Advanced Solid Tumor resistant detail...
KIT D816V Cabozantinib Advanced Solid Tumor resistant detail...
KIT D816H Regorafenib Advanced Solid Tumor resistant detail...
KIT D816V Quizartinib Advanced Solid Tumor resistant detail...
Unknown unknown Belinostat Advanced Solid Tumor not applicable detail...
AKT1 amp ONC201 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Carboplatin + Paclitaxel + Panobinostat Advanced Solid Tumor not applicable detail...
Unknown unknown Romidepsin Advanced Solid Tumor not applicable detail...
Unknown unknown Epirubicin + Valproic acid Advanced Solid Tumor not applicable detail...
Unknown unknown Afuresertib + Trametinib Advanced Solid Tumor not applicable detail...
Unknown unknown OBP-801 Advanced Solid Tumor not applicable detail...
Unknown unknown Birinapant Advanced Solid Tumor not applicable detail...
RET rearrange RXDX-105 Advanced Solid Tumor sensitive detail...
Unknown unknown MLN1117 + Sapanisertib Advanced Solid Tumor not applicable detail...
EGFR C797S EGFR exon 19 del EGFR T790M Osimertinib Advanced Solid Tumor resistant detail...
EGFR C797S EGFR exon 19 del EGFR T790M Rociletinib Advanced Solid Tumor resistant detail...
EGFR C797S EGFR L858R EGFR T790M Osimertinib Advanced Solid Tumor resistant detail...
EGFR C797S EGFR L858R EGFR T790M Rociletinib Advanced Solid Tumor resistant detail...
EGFR E709K Afatinib Advanced Solid Tumor sensitive detail...
EGFR E709K Dacomitinib Advanced Solid Tumor sensitive detail...
EGFR E709K Neratinib Advanced Solid Tumor sensitive detail...
EGFR E709K Gefitinib Advanced Solid Tumor decreased response detail...
EGFR E709K Erlotinib Advanced Solid Tumor decreased response detail...
EGFR E709K Osimertinib Advanced Solid Tumor decreased response detail...
EGFR E709K Rociletinib Advanced Solid Tumor decreased response detail...
EGFR G719A Dacomitinib Advanced Solid Tumor sensitive detail...
EGFR G719A Gefitinib Advanced Solid Tumor decreased response detail...
EGFR G719A Afatinib Advanced Solid Tumor sensitive detail...
EGFR G719A Erlotinib Advanced Solid Tumor decreased response detail...
EGFR G719A Osimertinib Advanced Solid Tumor decreased response detail...
EGFR G719A Rociletinib Advanced Solid Tumor decreased response detail...
EGFR G719A Neratinib Advanced Solid Tumor sensitive detail...
EGFR E709_T710delinsD Neratinib Advanced Solid Tumor sensitive detail...
EGFR E709_T710delinsD Dacomitinib Advanced Solid Tumor sensitive detail...
EGFR E709_T710delinsD Afatinib Advanced Solid Tumor sensitive detail...
EGFR E709_T710delinsD Erlotinib Advanced Solid Tumor decreased response detail...
EGFR E709_T710delinsD Rociletinib Advanced Solid Tumor decreased response detail...
EGFR E709_T710delinsD Osimertinib Advanced Solid Tumor decreased response detail...
EGFR E709_T710delinsD Gefitinib Advanced Solid Tumor decreased response detail...
PTEN del GSK2636771 Advanced Solid Tumor no benefit detail...
EGFR amp Depatuxizumab mafodotin Advanced Solid Tumor sensitive detail...
Unknown unknown Ulixertinib Advanced Solid Tumor not applicable detail...
PIK3CA mutant AZD8835 Advanced Solid Tumor sensitive detail...
Unknown unknown Panulisib Advanced Solid Tumor not applicable detail...
Unknown unknown Pri-724 Advanced Solid Tumor not applicable detail...
ETV6-NTRK3 Lestaurtinib Advanced Solid Tumor sensitive detail...
PIK3CA mutant Uprosertib Advanced Solid Tumor predicted - sensitive detail...
RB1 loss Palbociclib Advanced Solid Tumor no benefit detail...
Unknown unknown XL228 Advanced Solid Tumor not applicable detail...
Unknown unknown Conatumumab + Ganitumab Advanced Solid Tumor not applicable detail...
EGFR L858R TAE226 Advanced Solid Tumor sensitive detail...
Unknown unknown CHR-3996 Advanced Solid Tumor not applicable detail...
TP53 R175H ReACp53 Advanced Solid Tumor sensitive detail...
ETV6-NTRK3 BMS-536924 Advanced Solid Tumor sensitive detail...
Unknown unknown Derazantinib Advanced Solid Tumor not applicable detail...
FGFR2 wild-type AZ6089 Advanced Solid Tumor predicted - sensitive detail...
FGFR3 over exp LY2874455 Advanced Solid Tumor sensitive detail...
FGFR3 K650E PD98059 Advanced Solid Tumor sensitive detail...
FGFR1 act mut Erdafitinib Advanced Solid Tumor sensitive detail...
FGFR2 act mut Erdafitinib Advanced Solid Tumor sensitive detail...
FGFR3 act mut Erdafitinib Advanced Solid Tumor sensitive detail...
Unknown unknown RO4987655 Advanced Solid Tumor not applicable detail...
Unknown unknown SSR128129E Advanced Solid Tumor not applicable detail...
Unknown unknown TAK-733 Advanced Solid Tumor not applicable detail...
FGFR3 fusion TAS-120 Advanced Solid Tumor predicted - sensitive detail...
FGFR1 V561M FIIN-1 Advanced Solid Tumor sensitive detail...
FGFR1 fusion Dovitinib Advanced Solid Tumor sensitive detail...
Unknown unknown Pimasertib Advanced Solid Tumor not applicable detail...
Unknown unknown CI-1040 Advanced Solid Tumor not applicable detail...
Unknown unknown BAY1161909 Advanced Solid Tumor not applicable detail...
Unknown unknown BAY1217389 Advanced Solid Tumor not applicable detail...
Unknown unknown CFI-401870 Advanced Solid Tumor not applicable detail...
FGFR2-AHCYL1 BGJ398 Advanced Solid Tumor sensitive detail...
FGFR2-AHCYL1 PD173074 Advanced Solid Tumor sensitive detail...
FGFR2-BICC1 BGJ398 Advanced Solid Tumor sensitive detail...
FGFR2-BICC1 PD173074 Advanced Solid Tumor sensitive detail...
PIK3CA Q546K Trametinib Advanced Solid Tumor sensitive detail...
PIK3CA N345K Trametinib Advanced Solid Tumor sensitive detail...
PIK3CA H1047R Trametinib Advanced Solid Tumor sensitive detail...
PIK3CA G1049R Trametinib Advanced Solid Tumor sensitive detail...
PIK3CA E545K Trametinib Advanced Solid Tumor sensitive detail...
Unknown unknown Necitumumab Advanced Solid Tumor not applicable detail...
KIT H697Y Sunitinib Advanced Solid Tumor sensitive detail...
KIT H697Y Imatinib Advanced Solid Tumor decreased response detail...
KIT V560del Imatinib Advanced Solid Tumor sensitive detail...
KIT V560del Sunitinib Advanced Solid Tumor sensitive detail...
EGFR positive AC480 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown APTO-253 Advanced Solid Tumor not applicable detail...
Unknown unknown LY2275796 Advanced Solid Tumor no benefit detail...
PTEN del CC-223 Advanced Solid Tumor sensitive detail...
Unknown unknown Linsitinib Advanced Solid Tumor not applicable detail...
Unknown unknown KW-2450 Advanced Solid Tumor not applicable detail...
EGFR G696_P1033dup Erlotinib Advanced Solid Tumor sensitive detail...
EGFR G696_P1033dup Osimertinib Advanced Solid Tumor sensitive detail...
EGFR G696_P1033dup Afatinib Advanced Solid Tumor sensitive detail...
Unknown unknown Defactinib Advanced Solid Tumor not applicable detail...
CSF3R T640N Ruxolitinib Advanced Solid Tumor sensitive detail...
CSF3R T618I Ruxolitinib Advanced Solid Tumor sensitive detail...
Unknown unknown BI 853520 Advanced Solid Tumor not applicable detail...
Unknown unknown PF-00562271 Advanced Solid Tumor not applicable detail...
Unknown unknown SST0116CL1 Advanced Solid Tumor not applicable detail...
MET E168D SU11274 Advanced Solid Tumor sensitive detail...
Unknown unknown LMP400 Advanced Solid Tumor not applicable detail...
Unknown unknown GDC-0917 Advanced Solid Tumor not applicable detail...
Unknown unknown BIND-014 Advanced Solid Tumor not applicable detail...
Unknown unknown HGS1029 Advanced Solid Tumor not applicable detail...
EGFR wild-type Gefitinib Advanced Solid Tumor decreased response detail...
EGFR L858R Gefitinib Advanced Solid Tumor sensitive detail...
EGFR wild-type Erlotinib Advanced Solid Tumor decreased response detail...
EGFR L858R Erlotinib Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins Pexidartinib Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 F691L Pexidartinib Advanced Solid Tumor sensitive detail...
FLT3 D835V Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835Y Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835V Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835F Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 Y842H Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 M664I Pexidartinib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 M664I FLT3 F691L Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 N676S Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 N676S FLT3 F691L Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D698N Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D698N Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 R834Q Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 R834Q Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835E Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D835E Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835G Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D835G Pexidartinib Advanced Solid Tumor resistant detail...
Unknown unknown OSU03012 Advanced Solid Tumor not applicable detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D835H Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835H Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D835N Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D835N Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D835Y Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D839A Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D839A Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D839G Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D839H Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 D839N Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 D839N Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 N841K Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 N841K Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 Y842C Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 Y842H Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 Y842S Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 Y842S Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 R845G Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 R845G Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 G846R Pexidartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L FLT3 G846R Pexidartinib Advanced Solid Tumor resistant detail...
Unknown unknown Sulfatinib Advanced Solid Tumor not applicable detail...
Unknown unknown Ralimetinib Advanced Solid Tumor not applicable detail...
PTEN dec exp GSK2636771 Advanced Solid Tumor sensitive detail...
Unknown unknown ON123300 Advanced Solid Tumor not applicable detail...
Unknown unknown RTA-408 Advanced Solid Tumor not applicable detail...
TP53 R248Q Ganetespib Advanced Solid Tumor sensitive detail...
TP53 R175H Alvespimycin + Vorinostat Advanced Solid Tumor sensitive detail...
SMO D384A MRT-92 Advanced Solid Tumor predicted - resistant detail...
SMO Y394A MRT-92 Advanced Solid Tumor predicted - resistant detail...
SMO R400A MRT-92 Advanced Solid Tumor predicted - sensitive detail...
SMO E518K MRT-92 Advanced Solid Tumor predicted - resistant detail...
SMO L325F MRT-92 Advanced Solid Tumor predicted - resistant detail...
SMO V329F MRT-92 Advanced Solid Tumor predicted - resistant detail...
SMO T466F MRT-92 Advanced Solid Tumor predicted - resistant detail...
SMO M525G MRT-92 Advanced Solid Tumor predicted - resistant detail...
FLT3 D835Y Pexidartinib Advanced Solid Tumor resistant detail...
Unknown unknown MLN4924 Advanced Solid Tumor not applicable detail...
Unknown unknown TVB-2640 Advanced Solid Tumor not applicable detail...
PTEN loss SAR260301 Advanced Solid Tumor no benefit detail...
DDR2 L63V Dasatinib Advanced Solid Tumor sensitive detail...
DDR2 L239R Dasatinib Advanced Solid Tumor sensitive detail...
DDR2 G253C Dasatinib Advanced Solid Tumor sensitive detail...
DDR2 G505S Dasatinib Advanced Solid Tumor sensitive detail...
DDR2 G774V Dasatinib Advanced Solid Tumor sensitive detail...
DDR2 I638F Dasatinib Advanced Solid Tumor sensitive detail...
DDR2 I638F Ponatinib Advanced Solid Tumor sensitive detail...
DDR2 L239R Ponatinib Advanced Solid Tumor sensitive detail...
DDR2 G505S Ponatinib Advanced Solid Tumor sensitive detail...
DDR2 G774V Ponatinib Advanced Solid Tumor sensitive detail...
DDR2 G253C Ponatinib Advanced Solid Tumor sensitive detail...
DDR2 L63V Ponatinib Advanced Solid Tumor sensitive detail...
DDR2 L63V Nilotinib + Saracatinib Advanced Solid Tumor sensitive detail...
DDR2 I638F Nilotinib + Saracatinib Advanced Solid Tumor sensitive detail...
DDR2 G253C Nilotinib + Saracatinib Advanced Solid Tumor sensitive detail...
DDR2 G505S Nilotinib + Saracatinib Advanced Solid Tumor sensitive detail...
DDR2 G774V Nilotinib + Saracatinib Advanced Solid Tumor sensitive detail...
DDR2 L239R Nilotinib + Saracatinib Advanced Solid Tumor sensitive detail...
RET C634Y HG-6-63-01 Advanced Solid Tumor sensitive detail...
RET C634Y XMD15-44 Advanced Solid Tumor sensitive detail...
RET C634Y ALW-II-41-27 Advanced Solid Tumor sensitive detail...
RET M918T HG-6-63-01 Advanced Solid Tumor sensitive detail...
RET M918T XMD15-44 Advanced Solid Tumor sensitive detail...
RET M918T ALW-II-41-27 Advanced Solid Tumor sensitive detail...
Unknown unknown F14512 Advanced Solid Tumor not applicable detail...
Unknown unknown IPI-549 Advanced Solid Tumor not applicable detail...
Unknown unknown AZD8055 Advanced Solid Tumor not applicable detail...
PIK3CA mutant GDC-0980 Advanced Solid Tumor sensitive detail...
PIK3CA act mut GSK1059615 Advanced Solid Tumor sensitive detail...
Unknown unknown S-49076 Advanced Solid Tumor not applicable detail...
Unknown unknown Docetaxel + Glesatinib Advanced Solid Tumor not applicable detail...
Unknown unknown Erlotinib + Glesatinib Advanced Solid Tumor not applicable detail...
EML4-ALK ALK I1171S Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171S Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171S Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK I1171S Ceritinib Advanced Solid Tumor conflicting detail...
NPM1-ALK ALK I1171S Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK I1171S Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK I1171S Brigatinib Advanced Solid Tumor conflicting detail...
NPM1-ALK ALK I1171S Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171S ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171S ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171S AZD3463 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171S AZD3463 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174L Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174L Crizotinib Advanced Solid Tumor conflicting detail...
NPM1-ALK ALK F1174L Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174L Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174L Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174L Alectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174L Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174L Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174L ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174L ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174L AZD3463 Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174L AZD3463 Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK R1192P Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK R1192P Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK R1192P Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK R1192P Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK R1192P ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK R1192P AZD3463 Advanced Solid Tumor decreased response detail...
EML4-ALK ALK R1192P Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK R1192P Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK R1192P Alectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK R1192P Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK R1192P ASP3026 Advanced Solid Tumor resistant detail...
EML4-ALK ALK R1192P AZD3463 Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK T1151M Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK T1151M Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK T1151M Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK T1151M Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK T1151M ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK T1151M AZD3463 Advanced Solid Tumor resistant detail...
EML4-ALK ALK T1151M Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK T1151M Alectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK T1151M Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK T1151M AZD3463 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK T1151M Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK T1151M ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK G1269A Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK G1269A Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK G1269A Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK G1269A Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK G1269A ASP3026 Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK G1269A AZD3463 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1269A Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1269A Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1269A Alectinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK G1269A ASP3026 Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1269A Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1269A AZD3463 Advanced Solid Tumor sensitive detail...
Unknown unknown PKI-402 Advanced Solid Tumor not applicable detail...
Unknown unknown OPB-31121 Advanced Solid Tumor not applicable detail...
Unknown unknown Napabucasin Advanced Solid Tumor not applicable detail...
NPM1-ALK ALK I1171N ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171T ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK G1128S ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK E1210K ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ALK D1203N ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174I ASP3026 Advanced Solid Tumor resistant detail...
NPM1-ALK ALK N1178H ASP3026 Advanced Solid Tumor decreased response detail...
NPM1-ALK ALK G1128S Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK C1156F Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171N Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171T Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK N1178H Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK E1210K Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ALK D1203N Brigatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK F1174I Alectinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK N1178H Alectinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174I Brigatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK C1156F Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171N Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171T Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK E1210K Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ALK D1203N Alectinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK G1128S Alectinib Advanced Solid Tumor resistant detail...
Unknown unknown Ch282-5 Advanced Solid Tumor not applicable detail...
NPM1-ALK ALK G1128S Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171N Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171T Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ALK D1203N Crizotinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174I Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK N1178H Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK E1210K Crizotinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174I Ceritinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK G1128S Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171N Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171T Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK N1178H Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK E1210K Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ALK D1203N Ceritinib Advanced Solid Tumor resistant detail...
NPM1-ALK Lorlatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK F1174I Lorlatinib Advanced Solid Tumor sensitive detail...
NPM1-ALK ALK G1128S Lorlatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F Lorlatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171N Lorlatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK I1171T Lorlatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK N1178H Lorlatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK E1210K Lorlatinib Advanced Solid Tumor resistant detail...
NPM1-ALK ALK C1156F ALK D1203N Lorlatinib Advanced Solid Tumor resistant detail...
ATM loss YU238259 Advanced Solid Tumor sensitive detail...
Unknown unknown MK2206 + Paclitaxel Advanced Solid Tumor not applicable detail...
MET amp N/A Advanced Solid Tumor not applicable detail...
MET amp AMG 337 Advanced Solid Tumor conflicting detail...
MET amp EMD 1204831 Advanced Solid Tumor decreased response detail...
TP53 wild-type CTX-1 Advanced Solid Tumor sensitive detail...
TP53 loss CTX-1 Advanced Solid Tumor decreased response detail...
TP53 mutant CTX-1 Advanced Solid Tumor sensitive detail...
TP53 wild-type CTX-1 + Nutlin-3 Advanced Solid Tumor sensitive detail...
Unknown unknown Metformin + Temsirolimus Advanced Solid Tumor not applicable detail...
ETV6-NTRK2 Entrectinib Advanced Solid Tumor sensitive detail...
ETV6-NTRK3 Entrectinib Advanced Solid Tumor sensitive detail...
ETV6-ROS1 Entrectinib Advanced Solid Tumor sensitive detail...
ETV6-ALK Entrectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK C1156Y Entrectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1196M Entrectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1202R Entrectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1269A Entrectinib Advanced Solid Tumor decreased response detail...
EGFR S768_D770dup Nazartinib Advanced Solid Tumor sensitive detail...
EGFR A767_V769dup Nazartinib Advanced Solid Tumor sensitive detail...
EGFR N771_H773dup Nazartinib Advanced Solid Tumor sensitive detail...
EGFR exon 20 ins Nazartinib Advanced Solid Tumor predicted - sensitive detail...
EML4-ALK ALK L1198F Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK C1156Y ALK L1198F Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK C1156Y Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK C1156Y ALK L1198F Lorlatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1198F Lorlatinib Advanced Solid Tumor decreased response detail...
EML4-ALK Alectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F Alectinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK C1156Y ALK L1198F Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK C1156Y Ceritinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK L1198F Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK C1156Y ALK L1198F Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK C1156Y ALK L1198F Brigatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK C1156Y Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174C Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174C ALK L1198F Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174C Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174C ALK L1198F Lorlatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174C Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174C ALK L1198F Brigatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174C Ceritinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK F1174C ALK L1198F Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK F1174C Alectinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK F1174C ALK L1198F Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M Alectinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK L1196M Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1196M ALK L1198F Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M ALK L1198F Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M ALK L1198F Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M ALK L1198F Lorlatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M ALK L1198F Brigatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1196M Lorlatinib Advanced Solid Tumor conflicting detail...
EML4-ALK ALK G1202R Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1202R Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1202R Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1202R Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F ALK G1202R Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F ALK G1202R Lorlatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1198F ALK G1202R Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1198F ALK G1202R Brigatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1198F ALK G1202R Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1269A Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F ALK G1269A Crizotinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F ALK G1269A Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1198F ALK G1269A Lorlatinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1198F ALK G1269A Ceritinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1198F ALK G1269A Alectinib Advanced Solid Tumor resistant detail...
EGFR exon 19 del EGFR T790M Gefitinib Advanced Solid Tumor resistant detail...
EGFR exon 19 del EGFR T790M WZ4002 Advanced Solid Tumor sensitive detail...
EGFR exon 19 del EGFR T790M Afatinib Advanced Solid Tumor sensitive detail...
EGFR C797S EGFR exon 19 del Gefitinib Advanced Solid Tumor sensitive detail...
EGFR C797S EGFR exon 19 del Afatinib Advanced Solid Tumor sensitive detail...
EGFR C797S EGFR exon 19 del WZ4002 Advanced Solid Tumor resistant detail...
EGFR C797S EGFR exon 19 del EGFR T790M Gefitinib Advanced Solid Tumor conflicting detail...
EGFR C797S EGFR exon 19 del EGFR T790M WZ4002 Advanced Solid Tumor conflicting detail...
EGFR C797S EGFR exon 19 del EGFR T790M Gefitinib + WZ4002 Advanced Solid Tumor conflicting detail...
EGFR C797S EGFR exon 19 del EGFR T790M Afatinib Advanced Solid Tumor resistant detail...
JAK2 over exp MPL over exp Ruxolitinib + ZSTK474 Advanced Solid Tumor sensitive detail...
JAK2 V617F MPL wild-type Ruxolitinib + ZSTK474 Advanced Solid Tumor sensitive detail...
MPL W515L Ruxolitinib + ZSTK474 Advanced Solid Tumor sensitive detail...
JAK2 V617F Ruxolitinib + ZSTK474 Advanced Solid Tumor sensitive detail...
JAK2 over exp Ruxolitinib + ZSTK474 Advanced Solid Tumor sensitive detail...
JAK2 over exp MPL over exp Pictilisib + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 V617F MPL wild-type Pictilisib + Ruxolitinib Advanced Solid Tumor sensitive detail...
MPL W515L Pictilisib + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 over exp Pictilisib + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 V617F Pictilisib + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 over exp MPL over exp BEZ235 + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 V617F MPL wild-type BEZ235 + Ruxolitinib Advanced Solid Tumor sensitive detail...
MPL W515L BEZ235 + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 over exp BEZ235 + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 V617F BEZ235 + Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK2 over exp MPL over exp Ruxolitinib + TGX-221 Advanced Solid Tumor sensitive detail...
JAK2 V617F MPL wild-type Ruxolitinib + TGX-221 Advanced Solid Tumor sensitive detail...
MPL W515L Ruxolitinib + TGX-221 Advanced Solid Tumor sensitive detail...
JAK2 V617F Ruxolitinib + TGX-221 Advanced Solid Tumor sensitive detail...
JAK2 over exp Ruxolitinib + TGX-221 Advanced Solid Tumor sensitive detail...
ALK wild-type Repotrectinib Advanced Solid Tumor sensitive detail...
ALK G1202R Repotrectinib Advanced Solid Tumor sensitive detail...
ALK L1196M Repotrectinib Advanced Solid Tumor sensitive detail...
EML4-ALK SRC pos Ceritinib Advanced Solid Tumor resistant detail...
ALK G1128A Brigatinib Advanced Solid Tumor sensitive detail...
ALK I1171N Brigatinib Advanced Solid Tumor sensitive detail...
ALK F1174L Brigatinib Advanced Solid Tumor sensitive detail...
ALK R1192P Brigatinib Advanced Solid Tumor sensitive detail...
ALK F1245C Brigatinib Advanced Solid Tumor sensitive detail...
ALK R1275Q Brigatinib Advanced Solid Tumor sensitive detail...
ALK Y1278S Brigatinib Advanced Solid Tumor sensitive detail...
ALK G1269A Brigatinib Advanced Solid Tumor sensitive detail...
Unknown unknown Panvotinib-401 Advanced Solid Tumor not applicable detail...
Unknown unknown KX2-391 Advanced Solid Tumor not applicable detail...
EGFR act mut AP32788 Advanced Solid Tumor sensitive detail...
EGFR exon 20 ins AP32788 Advanced Solid Tumor sensitive detail...
ERBB2 exon 20 ins AP32788 Advanced Solid Tumor sensitive detail...
EGFR G719A AP32788 Advanced Solid Tumor sensitive detail...
ERBB2 G776V AP32788 Advanced Solid Tumor sensitive detail...
Unknown unknown TAS-115 Advanced Solid Tumor not applicable detail...
PIK3CA H1047R Sirolimus Advanced Solid Tumor sensitive detail...
Unknown unknown YW3-56 Advanced Solid Tumor not applicable detail...
Unknown unknown Lapatinib + MK2206 Advanced Solid Tumor not applicable detail...
Unknown unknown Docetaxel + MK-5108 Advanced Solid Tumor no benefit detail...
Unknown unknown GW5074 + Sorafenib Advanced Solid Tumor not applicable detail...
SMO D473H TAK-441 Advanced Solid Tumor predicted - sensitive detail...
PIK3CA E545K GDC-0980 Advanced Solid Tumor sensitive detail...
RET C634R Pz-1 Advanced Solid Tumor sensitive detail...
RET M918T Pz-1 Advanced Solid Tumor predicted - sensitive detail...
RET V804L Pz-1 Advanced Solid Tumor predicted - sensitive detail...
RET V804M Pz-1 Advanced Solid Tumor predicted - sensitive detail...
KDR wild-type Pz-1 Advanced Solid Tumor predicted - sensitive detail...
HRAS G12V Pz-1 Advanced Solid Tumor sensitive detail...
Unknown unknown NSC156529 Advanced Solid Tumor not applicable detail...
SMO C469Y Vismodegib Advanced Solid Tumor decreased response detail...
SMO I408V Vismodegib Advanced Solid Tumor decreased response detail...
SMO A459V Vismodegib Advanced Solid Tumor decreased response detail...
SMO T241M Vismodegib Advanced Solid Tumor decreased response detail...
SMO T241M Taladegib Advanced Solid Tumor decreased response detail...
SMO W281C Taladegib Advanced Solid Tumor decreased response detail...
SMO V321M Taladegib Advanced Solid Tumor decreased response detail...
SMO I408V Taladegib Advanced Solid Tumor decreased response detail...
SMO A459V Taladegib Advanced Solid Tumor decreased response detail...
SMO C469Y Taladegib Advanced Solid Tumor decreased response detail...
SMO C469Y Sonidegib Advanced Solid Tumor decreased response detail...
SMO A459V Sonidegib Advanced Solid Tumor decreased response detail...
SMO I408V Sonidegib Advanced Solid Tumor decreased response detail...
SMO V321M Sonidegib Advanced Solid Tumor decreased response detail...
SMO W281C Sonidegib Advanced Solid Tumor decreased response detail...
SMO T241M Sonidegib Advanced Solid Tumor decreased response detail...
SMO C469Y JQ1 Advanced Solid Tumor sensitive detail...
SMO A459V JQ1 Advanced Solid Tumor sensitive detail...
SMO I408V JQ1 Advanced Solid Tumor sensitive detail...
SMO V321M JQ1 Advanced Solid Tumor sensitive detail...
SMO W281C JQ1 Advanced Solid Tumor sensitive detail...
SMO T241M JQ1 Advanced Solid Tumor sensitive detail...
BRAF mutant XL147 Advanced Solid Tumor decreased response detail...
SMO D473G Vismodegib Advanced Solid Tumor resistant detail...
SMO E518K Vismodegib Advanced Solid Tumor resistant detail...
SMO S387N Vismodegib Advanced Solid Tumor resistant detail...
SMO S387N Sonidegib Advanced Solid Tumor resistant detail...
SMO D384N Sonidegib Advanced Solid Tumor resistant detail...
SMO N219D Sonidegib Advanced Solid Tumor resistant detail...
SMO D384N Vismodegib Advanced Solid Tumor resistant detail...
SMO E518K Sonidegib Advanced Solid Tumor decreased response detail...
SMO W535L Posaconazole Advanced Solid Tumor resistant detail...
SMO D473G Posaconazole Advanced Solid Tumor sensitive detail...
SMO E518K Posaconazole Advanced Solid Tumor sensitive detail...
SMO S387N Posaconazole Advanced Solid Tumor sensitive detail...
SMO D384N Posaconazole Advanced Solid Tumor sensitive detail...
SMO N219D Posaconazole Advanced Solid Tumor sensitive detail...
SMO N219D Arsenic trioxide + Posaconazole Advanced Solid Tumor sensitive detail...
SMO D384N Arsenic trioxide + Posaconazole Advanced Solid Tumor sensitive detail...
SMO S387N Arsenic trioxide + Posaconazole Advanced Solid Tumor sensitive detail...
SMO E518K Arsenic trioxide + Posaconazole Advanced Solid Tumor sensitive detail...
SMO D473G Arsenic trioxide + Posaconazole Advanced Solid Tumor sensitive detail...
KIT act mut PLX9486 Advanced Solid Tumor sensitive detail...
Unknown unknown Refametinib + Sorafenib Advanced Solid Tumor not applicable detail...
ATM inact mut E7449 Advanced Solid Tumor sensitive detail...
ATRX inact mut E7449 Advanced Solid Tumor sensitive detail...
Unknown unknown Resminostat Advanced Solid Tumor not applicable detail...
Unknown unknown 4SC-205 Advanced Solid Tumor not applicable detail...
Unknown unknown Alpelisib + BGJ398 Advanced Solid Tumor not applicable detail...
Unknown unknown Paclitaxel + TVB-2640 Advanced Solid Tumor not applicable detail...
Unknown unknown VX-970 Advanced Solid Tumor not applicable detail...
Unknown unknown Carboplatin + VX-970 Advanced Solid Tumor not applicable detail...
EGFR act mut ABT-806 Advanced Solid Tumor predicted - sensitive detail...
ROS1 rearrange Entrectinib Advanced Solid Tumor sensitive detail...
ALK rearrange Entrectinib Advanced Solid Tumor sensitive detail...
KIT V654A Imatinib Advanced Solid Tumor resistant detail...
KIT V559D Ponatinib Advanced Solid Tumor sensitive detail...
KIT V560G Ponatinib Advanced Solid Tumor sensitive detail...
KIT T670I Ponatinib Advanced Solid Tumor sensitive detail...
KIT D816H Ponatinib Advanced Solid Tumor sensitive detail...
KIT D820E Ponatinib Advanced Solid Tumor sensitive detail...
KIT A829P Ponatinib Advanced Solid Tumor sensitive detail...
KIT V654A Ponatinib Advanced Solid Tumor sensitive detail...
KIT V560D Ponatinib Advanced Solid Tumor sensitive detail...
KIT V560D Sunitinib Advanced Solid Tumor sensitive detail...
KIT V560D Imatinib Advanced Solid Tumor sensitive detail...
KIT V560D Regorafenib Advanced Solid Tumor sensitive detail...
KIT exon 9 Ponatinib Advanced Solid Tumor sensitive detail...
KIT exon 9 Sunitinib Advanced Solid Tumor sensitive detail...
KIT exon 9 Imatinib Advanced Solid Tumor resistant detail...
KIT exon 9 Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del Sunitinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del Imatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del Regorafenib Advanced Solid Tumor sensitive detail...
KIT K550_W557del Ponatinib Advanced Solid Tumor sensitive detail...
KIT K550_W557del Sunitinib Advanced Solid Tumor sensitive detail...
KIT K550_W557del Imatinib Advanced Solid Tumor sensitive detail...
KIT K550_W557del Regorafenib Advanced Solid Tumor sensitive detail...
KIT P551_E554del Ponatinib Advanced Solid Tumor sensitive detail...
KIT T417_D419delinsI Imatinib Advanced Solid Tumor conflicting detail...
KIT P551_E554del Sunitinib Advanced Solid Tumor resistant detail...
KIT P551_E554del Imatinib Advanced Solid Tumor resistant detail...
KIT P551_E554del Regorafenib Advanced Solid Tumor resistant detail...
KIT K558delinsNP Ponatinib Advanced Solid Tumor sensitive detail...
KIT K558delinsNP Sunitinib Advanced Solid Tumor sensitive detail...
KIT K558delinsNP Imatinib Advanced Solid Tumor sensitive detail...
KIT K558delinsNP Regorafenib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT V654A Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT V654A Sunitinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT V654A Imatinib Advanced Solid Tumor no benefit detail...
KIT W557_K558del KIT V654A Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT T670I Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT T670I Sunitinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT T670I Imatinib Advanced Solid Tumor no benefit detail...
KIT W557_K558del KIT T670I Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D816H Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT D816H Sunitinib Advanced Solid Tumor decreased response detail...
KIT W557_K558del KIT D816H Imatinib Advanced Solid Tumor decreased response detail...
KIT W557_K558del KIT D816H Regorafenib Advanced Solid Tumor decreased response detail...
BRAF V600E BRAF T529I SB590885 Advanced Solid Tumor predicted - resistant detail...
BRAF V600E SB590885 Advanced Solid Tumor sensitive detail...
BRAF V600E BRAF T529M SB590885 Advanced Solid Tumor predicted - resistant detail...
BRAF V600E BRAF T529N RAF265 Advanced Solid Tumor resistant detail...
BRAF V600E BRAF T529I RAF265 Advanced Solid Tumor predicted - sensitive detail...
BRAF V600E BRAF T529M RAF265 Advanced Solid Tumor predicted - sensitive detail...
BRAF V600E RAF265 Advanced Solid Tumor sensitive detail...
BRAF V600E BRAF T529N SB590885 Advanced Solid Tumor resistant detail...
BRAF V600E BRAF T529M PLX4720 Advanced Solid Tumor predicted - resistant detail...
BRAF V600E BRAF T529I PLX4720 Advanced Solid Tumor predicted - resistant detail...
BRAF V600E PLX4720 Advanced Solid Tumor sensitive detail...
BRAF V600E BRAF T529N PLX4720 Advanced Solid Tumor resistant detail...
BRAF V600E BRAF T529N Sorafenib Advanced Solid Tumor conflicting detail...
BRAF V600E BRAF T529M Sorafenib Advanced Solid Tumor predicted - sensitive detail...
BRAF V600E BRAF T529I Sorafenib Advanced Solid Tumor predicted - sensitive detail...
BRAF V600E BRAF T529N CI-1040 Advanced Solid Tumor sensitive detail...
BRAF V600E BRAF T529M CI-1040 Advanced Solid Tumor predicted - sensitive detail...
BRAF V600E BRAF T529I CI-1040 Advanced Solid Tumor sensitive detail...
BRAF V600E CI-1040 Advanced Solid Tumor sensitive detail...
Unknown unknown Demcizumab Advanced Solid Tumor not applicable detail...
Unknown unknown LY3039478 Advanced Solid Tumor not applicable detail...
Unknown unknown Navicixizumab Advanced Solid Tumor not applicable detail...
KIT W557G Imatinib Advanced Solid Tumor sensitive detail...
KIT Y578C Imatinib Advanced Solid Tumor sensitive detail...
KIT W557C KIT Y578C Imatinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR E884K Erlotinib Advanced Solid Tumor decreased response detail...
EGFR N826S Erlotinib Advanced Solid Tumor resistant detail...
EGFR N826S Gefitinib Advanced Solid Tumor resistant detail...
EGFR N826S AEE788 Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D816G Ponatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820A Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT D820G Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT N822K Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT A829P Ponatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT D816G Sunitinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820A Sunitinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820G Sunitinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT N822K Sunitinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT A829P Sunitinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D816G Imatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820A Imatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820G Imatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT N822K Imatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT A829P Imatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D816G Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820A Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT D820G Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT N822K Regorafenib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT A829P Regorafenib Advanced Solid Tumor resistant detail...
EGFR A289V Erlotinib Advanced Solid Tumor sensitive detail...
EGFR T263P Erlotinib Advanced Solid Tumor sensitive detail...
EGFR R108K Erlotinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR E884K Gefitinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR E884K EKI-285 Advanced Solid Tumor sensitive detail...
EGFR E868G Erlotinib Advanced Solid Tumor sensitive detail...
EGFR R831H Erlotinib Advanced Solid Tumor sensitive detail...
ERBB2 T733I Lapatinib Advanced Solid Tumor resistant detail...
Unknown unknown Adavosertib + Olaparib Advanced Solid Tumor not applicable detail...
ERBB2 P780L Lapatinib Advanced Solid Tumor resistant detail...
NOTCH1 over exp Brontictuzumab Advanced Solid Tumor sensitive detail...
Unknown unknown PRN1371 Advanced Solid Tumor not applicable detail...
Unknown unknown ASP5878 Advanced Solid Tumor not applicable detail...
FGFR1 mutant Pemigatinib Advanced Solid Tumor sensitive detail...
PDGFRA D842Y Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA D842Y Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA V658A Imatinib Advanced Solid Tumor sensitive detail...
Unknown unknown Duligotuzumab Advanced Solid Tumor not applicable detail...
NRAS mutant BGB-283 Advanced Solid Tumor predicted - sensitive detail...
BRAF mutant BGB-283 Advanced Solid Tumor sensitive detail...
Unknown unknown Pemetrexed + Sorafenib Advanced Solid Tumor not applicable detail...
PTEN dec exp Pemetrexed + Sorafenib Advanced Solid Tumor predicted - sensitive detail...
ERBB2 S783P Lapatinib Advanced Solid Tumor resistant detail...
ERBB2 E717K Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 E719G Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 L726F Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 L785F Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 Y803N Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 E812K Lapatinib Advanced Solid Tumor decreased response detail...
ERBB2 E717K XL647 Advanced Solid Tumor sensitive detail...
ERBB2 E719G XL647 Advanced Solid Tumor sensitive detail...
ERBB2 L726F XL647 Advanced Solid Tumor sensitive detail...
ERBB2 T733I XL647 Advanced Solid Tumor sensitive detail...
ERBB2 L755S XL647 Advanced Solid Tumor sensitive detail...
ERBB2 P780L XL647 Advanced Solid Tumor sensitive detail...
ERBB2 S783P XL647 Advanced Solid Tumor sensitive detail...
ERBB2 L785F XL647 Advanced Solid Tumor sensitive detail...
ERBB2 T798I XL647 Advanced Solid Tumor sensitive detail...
ERBB2 Y803N XL647 Advanced Solid Tumor sensitive detail...
ERBB2 E812K XL647 Advanced Solid Tumor sensitive detail...
ERBB2 D821N XL647 Advanced Solid Tumor sensitive detail...
ERBB2 V839G XL647 Advanced Solid Tumor sensitive detail...
ERBB2 L915M XL647 Advanced Solid Tumor sensitive detail...
ERBB2 T798I Lapatinib Advanced Solid Tumor resistant detail...
Unknown unknown DS6051b Advanced Solid Tumor not applicable detail...
ETV6-NTRK3 Altiratinib Advanced Solid Tumor sensitive detail...
Unknown unknown Ganitumab Advanced Solid Tumor not applicable detail...
JAK3 V674A Ruxolitinib Advanced Solid Tumor sensitive detail...
JAK3 L857P Ruxolitinib Advanced Solid Tumor decreased response detail...
JAK3 L857P JAK3 Y100A Ruxolitinib Advanced Solid Tumor decreased response detail...
JAK3 L857P NIBR3049 Advanced Solid Tumor sensitive detail...
JAK3 L857P JAK3 Y100A NIBR3049 Advanced Solid Tumor sensitive detail...
JAK3 V674A NIBR3049 Advanced Solid Tumor decreased response detail...
JAK3 V674A Tofacitinib Advanced Solid Tumor sensitive detail...
JAK3 L857P Tofacitinib Advanced Solid Tumor sensitive detail...
JAK3 L857P JAK3 Y100A Tofacitinib Advanced Solid Tumor sensitive detail...
PDGFRA H845_N848delinsP Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA Y849S Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA D846Y Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA D842_I843delinsIM Imatinib Advanced Solid Tumor resistant detail...
PDGFRA R841_D842delinsKI Imatinib Advanced Solid Tumor resistant detail...
PDGFRA V561_I562insER Imatinib Advanced Solid Tumor sensitive detail...
PDGFRA S566_E571delinsR Imatinib Advanced Solid Tumor sensitive detail...
Unknown unknown Irinotecan + Veliparib Advanced Solid Tumor not applicable detail...
Unknown unknown Ixabepilone + Sunitinib Advanced Solid Tumor not applicable detail...
Unknown unknown A-1331852 + Docetaxel Advanced Solid Tumor not applicable detail...
Unknown unknown Fruquintinib Advanced Solid Tumor not applicable detail...
Unknown unknown Poloxin-2 Advanced Solid Tumor not applicable detail...
EGFR-RAD51 Afatinib Advanced Solid Tumor sensitive detail...
EGFR-RAD51 Osimertinib Advanced Solid Tumor predicted - sensitive detail...
EGFR-RAD51 Cetuximab Advanced Solid Tumor sensitive detail...
Unknown unknown NP-004255 Advanced Solid Tumor not applicable detail...
FGFR3 K650E AZD4547 Advanced Solid Tumor decreased response detail...
FGFR3 N540K AZD4547 Advanced Solid Tumor resistant detail...
FGFR3 K650E Erdafitinib Advanced Solid Tumor sensitive detail...
FGFR3 N540K Erdafitinib Advanced Solid Tumor sensitive detail...
FGFR3-TACC3 Erdafitinib Advanced Solid Tumor sensitive detail...
FGFR3-TACC3 AZD4547 Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR T790M EAI045 Advanced Solid Tumor sensitive detail...
EGFR L858R EAI045 Advanced Solid Tumor sensitive detail...
EGFR exon 19 del EGFR T790M EAI045 Advanced Solid Tumor resistant detail...
EGFR wild-type EAI045 Advanced Solid Tumor resistant detail...
EGFR I941R EGFR L858R EGFR T790M EAI045 Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR T790M Cetuximab + EAI045 Advanced Solid Tumor sensitive detail...
EGFR exon 19 del EGFR T790M Cetuximab + EAI045 Advanced Solid Tumor resistant detail...
EGFR C797S EGFR L858R EGFR T790M Cetuximab + EAI045 Advanced Solid Tumor sensitive detail...
Unknown unknown Bevacizumab + Sorafenib Advanced Solid Tumor not applicable detail...
Unknown unknown Parsaclisib Advanced Solid Tumor not applicable detail...
Unknown unknown Taselisib Advanced Solid Tumor not applicable detail...
Unknown unknown Vandetanib Advanced Solid Tumor not applicable detail...
Unknown unknown Bevacizumab + Cediranib Advanced Solid Tumor not applicable detail...
EGFR T34_A289del Erlotinib Advanced Solid Tumor sensitive detail...
EGFR T34_A289del Cetuximab Advanced Solid Tumor decreased response detail...
EZH2 A677G EZH2 Y111D Tazemetostat Advanced Solid Tumor resistant detail...
EZH2 A677G EZH2 Y111D GSK126 Advanced Solid Tumor resistant detail...
EZH2 Y111D EZH2 Y641F GSK126 Advanced Solid Tumor predicted - resistant detail...
EZH2 Y111D EZH2 Y641F Tazemetostat Advanced Solid Tumor decreased response detail...
EZH2 Y111D GSK126 Advanced Solid Tumor resistant detail...
EZH2 Y111D Tazemetostat Advanced Solid Tumor resistant detail...
EGFR exon 19 del BGB-283 Advanced Solid Tumor sensitive detail...
EGFR L858R BGB-283 Advanced Solid Tumor sensitive detail...
EGFR exon 19 del EGFR T790M BGB-283 Advanced Solid Tumor sensitive detail...
BRAF V600E BGB-283 Advanced Solid Tumor sensitive detail...
BRAF wild-type BGB-283 Advanced Solid Tumor resistant detail...
TP53 mutant AMG 232 Advanced Solid Tumor resistant detail...
TP53 wild-type AMG 232 Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1152R Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK S1206Y Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174L Lorlatinib Advanced Solid Tumor sensitive detail...
Unknown unknown OM-174 Advanced Solid Tumor not applicable detail...
TP53 positive p28 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Selectikine Advanced Solid Tumor not applicable detail...
Unknown unknown SU14813 Advanced Solid Tumor not applicable detail...
Unknown unknown TB-403 Advanced Solid Tumor not applicable detail...
ALK R1275Q Lorlatinib Advanced Solid Tumor sensitive detail...
ALK F1174L Lorlatinib Advanced Solid Tumor sensitive detail...
ALK F1245C Lorlatinib Advanced Solid Tumor sensitive detail...
FGFR2 mutant Pemigatinib Advanced Solid Tumor sensitive detail...
FGFR3 mutant Pemigatinib Advanced Solid Tumor sensitive detail...
FGFR2 wild-type PRN1371 Advanced Solid Tumor sensitive detail...
FGFR2 K660E PRN1371 Advanced Solid Tumor sensitive detail...
FGFR2 K660N PRN1371 Advanced Solid Tumor sensitive detail...
FGFR2 N550K PRN1371 Advanced Solid Tumor sensitive detail...
FGFR3 over exp PRN1371 Advanced Solid Tumor sensitive detail...
FGFR3 K650M PRN1371 Advanced Solid Tumor sensitive detail...
Unknown unknown Gemcitabine + Pazopanib Advanced Solid Tumor sensitive detail...
ATM inact mut Veliparib Advanced Solid Tumor sensitive detail...
Unknown unknown Marizomib Advanced Solid Tumor not applicable detail...
HRAS G12V Rigosertib Advanced Solid Tumor sensitive detail...
PIK3CA E545K Rigosertib Advanced Solid Tumor sensitive detail...
PIK3CA H1047R Rigosertib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171N Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK I1171N Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171N Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK I1171N Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171N Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171S Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK I1171T Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK I1171T Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1196M Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1202R Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1202del Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK G1202del Ceritinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK G1202del Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK G1202del Brigatinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK G1202del Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK D1203N Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK D1203N Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK D1203N Alectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK D1203N Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK D1203N Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK E1210K Ceritinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK E1210K Alectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK E1210K Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK E1210K Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK D1203N ALK F1174C Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK D1203N ALK F1174C Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK D1203N ALK F1174C Brigatinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK D1203N ALK F1174C Lorlatinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK D1203N ALK E1210K Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK D1203N ALK E1210K Ceritinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK D1203N ALK E1210K Alectinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK D1203N ALK E1210K Brigatinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK D1203N ALK E1210K Lorlatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK D1203N ALK F1174C Ceritinib Advanced Solid Tumor resistant detail...
KIT D816V BPR1J373 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Debio 0617B Advanced Solid Tumor not applicable detail...
PDGFRA D842V Crenolanib Advanced Solid Tumor sensitive detail...
PDGFRA D842V Nilotinib Advanced Solid Tumor resistant detail...
Unknown unknown Rucaparib Advanced Solid Tumor not applicable detail...
PDGFRA D842V Sunitinib Advanced Solid Tumor resistant detail...
PDGFRA D842V PDGFRA V561D Sunitinib Advanced Solid Tumor resistant detail...
FGFR2 positive BAY1187982 Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins Brigatinib Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 D835Y Brigatinib Advanced Solid Tumor sensitive detail...
EGFR L858R Brigatinib Advanced Solid Tumor sensitive detail...
EGFR L858R EGFR T790M Brigatinib Advanced Solid Tumor sensitive detail...
ROS1 fusion Brigatinib Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 F691L Brigatinib Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 F691I Brigatinib Advanced Solid Tumor decreased response detail...
EGFR E746_A750del Brigatinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR T790M Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK T1151dup Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1152R Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1152P Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK F1174V Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK S1206F Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK S1206Y Brigatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK T1151dup Crizotinib Advanced Solid Tumor resistant detail...
EML4-ALK ALK L1152P Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK F1174V Crizotinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK L1152R Ceritinib Advanced Solid Tumor decreased response detail...
EML4-ALK ALK L1152P Ceritinib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 N676D Midostaurin Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691I Midostaurin Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691I Sunitinib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 A848P Sunitinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691I Sorafenib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L Sorafenib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 A848P Sorafenib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 Y842H Sorafenib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 N676D Quizartinib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 Y842H Quizartinib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 A848P Quizartinib Advanced Solid Tumor decreased response detail...
FLT3 exon 14 ins FLT3 F691I Quizartinib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L Quizartinib Advanced Solid Tumor resistant detail...
Unknown unknown Adavosertib Advanced Solid Tumor not applicable detail...
TP53 mutant Adavosertib Advanced Solid Tumor sensitive detail...
Unknown unknown Adavosertib + Gemcitabine Advanced Solid Tumor not applicable detail...
Unknown unknown Adavosertib + Cisplatin Advanced Solid Tumor sensitive detail...
Unknown unknown Adavosertib + Carboplatin Advanced Solid Tumor not applicable detail...
EGFR R451C SYM004 Advanced Solid Tumor predicted - sensitive detail...
EGFR K467T SYM004 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown ONCOS-102 Advanced Solid Tumor not applicable detail...
Unknown unknown Copanlisib Advanced Solid Tumor not applicable detail...
BRAF G464E Vemurafenib Advanced Solid Tumor resistant detail...
BRAF G464V Vemurafenib Advanced Solid Tumor resistant detail...
BRAF G464R Vemurafenib Advanced Solid Tumor resistant detail...
BRAF G469A Vemurafenib Advanced Solid Tumor resistant detail...
BRAF G469V Vemurafenib Advanced Solid Tumor resistant detail...
BRAF L597V Vemurafenib Advanced Solid Tumor resistant detail...
BRAF L597Q Vemurafenib Advanced Solid Tumor resistant detail...
BRAF K601T Vemurafenib Advanced Solid Tumor resistant detail...
BRAF K601N Vemurafenib Advanced Solid Tumor resistant detail...
FLT3 exon 14 ins FLT3 F691L MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 D835Y MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 D835Y MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 D835V MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 Y842H MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 Y842C MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 D835F MRX-2843 Advanced Solid Tumor sensitive detail...
FLT3 exon 14 ins FLT3 D835V MRX-2843 Advanced Solid Tumor sensitive detail...
HRAS mutant Selumetinib Advanced Solid Tumor predicted - sensitive detail...
HRAS mutant Binimetinib Advanced Solid Tumor predicted - sensitive detail...
HRAS mutant Everolimus Advanced Solid Tumor predicted - sensitive detail...
HRAS Q61L Everolimus Advanced Solid Tumor sensitive detail...
HRAS Q61R Everolimus Advanced Solid Tumor sensitive detail...
HRAS G12V Everolimus Advanced Solid Tumor sensitive detail...
HRAS Q61R Binimetinib Advanced Solid Tumor sensitive detail...
HRAS Q61L Binimetinib Advanced Solid Tumor sensitive detail...
HRAS G12V Binimetinib Advanced Solid Tumor sensitive detail...
HRAS G12V Binimetinib + Everolimus Advanced Solid Tumor sensitive detail...
HRAS Q61L Binimetinib + Everolimus Advanced Solid Tumor sensitive detail...
Unknown unknown Rosmantuzumab Advanced Solid Tumor not applicable detail...
MET D1228V Savolitinib Advanced Solid Tumor resistant detail...
MET D1228V Crizotinib Advanced Solid Tumor resistant detail...
MET D1228V Capmatinib Advanced Solid Tumor resistant detail...
MET D1228V Cabozantinib Advanced Solid Tumor sensitive detail...
MET D1228V Glesatinib Advanced Solid Tumor sensitive detail...
MET D1228V Merestinib Advanced Solid Tumor sensitive detail...
MET act mut Altiratinib Advanced Solid Tumor sensitive detail...
MET act mut Glesatinib Advanced Solid Tumor sensitive detail...
BRAF mutant MLN2480 Advanced Solid Tumor predicted - sensitive detail...
NRAS G12D N-Arachidonoyl Dopamine Advanced Solid Tumor sensitive detail...
NRAS mutant NS1 Advanced Solid Tumor no benefit detail...
STK11 inact mut Selumetinib Advanced Solid Tumor sensitive detail...
STK11 inact mut Trametinib Advanced Solid Tumor sensitive detail...
STK11 inact mut RDEA119 Advanced Solid Tumor sensitive detail...
STK11 inact mut CI-1040 Advanced Solid Tumor sensitive detail...
STK11 inact mut PD-0325901 Advanced Solid Tumor sensitive detail...
Unknown unknown ABT-348 Advanced Solid Tumor not applicable detail...
PTEN inact mut Capivasertib Advanced Solid Tumor sensitive detail...
PTEN loss Capivasertib Advanced Solid Tumor sensitive detail...
Unknown unknown Afatinib + Vinorelbine Advanced Solid Tumor not applicable detail...
ETV6-SYK HMPL-523 Advanced Solid Tumor sensitive detail...
EGFR G719A EGFR T790M Afatinib Advanced Solid Tumor resistant detail...
EGFR E709_T710delinsD EGFR L792F Afatinib Advanced Solid Tumor resistant detail...
EGFR E709_T710delinsD EGFR L792F Dacomitinib Advanced Solid Tumor sensitive detail...
IDH1 R132H Talazoparib Advanced Solid Tumor sensitive detail...
IDH1 R132H VX-970 Advanced Solid Tumor sensitive detail...
IDH1 R132H Olaparib Advanced Solid Tumor sensitive detail...
IDH1 R132H Niraparib Advanced Solid Tumor sensitive detail...
IDH1 R132H Rucaparib Advanced Solid Tumor sensitive detail...
IDH1 R132H Cisplatin + Talazoparib Advanced Solid Tumor sensitive detail...
IDH1 R132H AGI-5198 + Talazoparib Advanced Solid Tumor decreased response detail...
Unknown unknown Citarinostat + Paclitaxel Advanced Solid Tumor not applicable detail...
Unknown unknown Entinostat Advanced Solid Tumor not applicable detail...
MET amp SYM015 Advanced Solid Tumor sensitive detail...
MET del exon14 SYM015 Advanced Solid Tumor sensitive detail...
MET positive ARGX-111 Advanced Solid Tumor sensitive detail...
MET positive Emibetuzumab Advanced Solid Tumor sensitive detail...
Unknown unknown Ficlatuzumab Advanced Solid Tumor not applicable detail...
MET Y1230C Merestinib Advanced Solid Tumor sensitive detail...
MET D1228N Merestinib Advanced Solid Tumor sensitive detail...
MET positive INCB028060 Advanced Solid Tumor sensitive detail...
TP53 wild-type HDM201 Advanced Solid Tumor sensitive detail...
Unknown unknown DS-3032b Advanced Solid Tumor not applicable detail...
EGFR L858R EGFR C797S Erlotinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR L792F Afatinib Advanced Solid Tumor decreased response detail...
EGFR L792F EGFR L858R Afatinib Advanced Solid Tumor decreased response detail...
Unknown unknown TTI-621 Advanced Solid Tumor not applicable detail...
ETV6-FGFR1 AZD4547 Advanced Solid Tumor sensitive detail...
ETV6-FGFR3 AZD4547 Advanced Solid Tumor sensitive detail...
ETV6-FGFR4 AZD4547 Advanced Solid Tumor sensitive detail...
Unknown unknown Navitoclax Advanced Solid Tumor not applicable detail...
MET D1228H Altiratinib Advanced Solid Tumor predicted - sensitive detail...
MET D1228N Altiratinib Advanced Solid Tumor predicted - sensitive detail...
MET Y1230H Altiratinib Advanced Solid Tumor predicted - sensitive detail...
MET Y1230D Altiratinib Advanced Solid Tumor predicted - sensitive detail...
MET M1250T Altiratinib Advanced Solid Tumor predicted - sensitive detail...
MET Y1230C Altiratinib Advanced Solid Tumor predicted - sensitive detail...
FGFR3 L608V BGJ398 Advanced Solid Tumor decreased response detail...
FGFR3 K650E BGJ398 Advanced Solid Tumor decreased response detail...
FGFR3 N540K BGJ398 Advanced Solid Tumor resistant detail...
FGFR3 V555L BGJ398 Advanced Solid Tumor decreased response detail...
FGFR3 V555M BGJ398 Advanced Solid Tumor resistant detail...
FGFR3 L608V Ponatinib Advanced Solid Tumor sensitive detail...
FGFR3 V555M Ponatinib Advanced Solid Tumor sensitive detail...
FGFR3 N540K Ponatinib Advanced Solid Tumor sensitive detail...
FGFR3 K650E Ponatinib Advanced Solid Tumor sensitive detail...
FGFR3 K650E Dovitinib Advanced Solid Tumor sensitive detail...
FGFR3 N540K Dovitinib Advanced Solid Tumor sensitive detail...
FGFR3 V555M Dovitinib Advanced Solid Tumor sensitive detail...
FGFR3 L608V Dovitinib Advanced Solid Tumor sensitive detail...
FGFR3 L608V AZD4547 Advanced Solid Tumor decreased response detail...
FGFR3 V555M AZD4547 Advanced Solid Tumor resistant detail...
FGFR3 L608V Debio 1347 Advanced Solid Tumor decreased response detail...
FGFR3 V555M Debio 1347 Advanced Solid Tumor decreased response detail...
FGFR3 N540K Debio 1347 Advanced Solid Tumor decreased response detail...
FGFR3 K650E Debio 1347 Advanced Solid Tumor sensitive detail...
FGFR3 L608V FIIN-2 Advanced Solid Tumor sensitive detail...
FGFR3 K650E FIIN-2 Advanced Solid Tumor sensitive detail...
FGFR3 V555M FIIN-2 Advanced Solid Tumor decreased response detail...
FGFR3 N540K FIIN-2 Advanced Solid Tumor decreased response detail...
FGFR3 L608V LY2874455 Advanced Solid Tumor sensitive detail...
FGFR3 V555M LY2874455 Advanced Solid Tumor sensitive detail...
FGFR3 K650E LY2874455 Advanced Solid Tumor sensitive detail...
FGFR3 N540K LY2874455 Advanced Solid Tumor decreased response detail...
FGFR2 V564F BGJ398 Advanced Solid Tumor resistant detail...
FGFR2 V564F Debio 1347 Advanced Solid Tumor sensitive detail...
FGFR2 V564F AZD4547 Advanced Solid Tumor resistant detail...
FGFR2 V564I Debio 1347 Advanced Solid Tumor resistant detail...
FGFR2 V564L Debio 1347 Advanced Solid Tumor resistant detail...
Unknown unknown Abexinostat + Pazopanib Advanced Solid Tumor not applicable detail...
BRAF V600E PF-00477736 + PF3644022 Advanced Solid Tumor predicted - sensitive detail...
EGFR L858R PF-00477736 + PF3644022 Advanced Solid Tumor no benefit detail...
CDKN2A loss PF-00477736 + PF3644022 Advanced Solid Tumor predicted - sensitive detail...
BRAF mutant PF-00477736 + PF3644022 Advanced Solid Tumor predicted - sensitive detail...
EGFR C797S EGFR L858R EGFR T790M Cetuximab Advanced Solid Tumor sensitive detail...
EGFR E746_A750del EGFR T790M EGFR C797S Cetuximab Advanced Solid Tumor no benefit detail...
ALK positive Belizatinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK L1196M Repotrectinib Advanced Solid Tumor sensitive detail...
EML4-ALK ALK G1202R Repotrectinib Advanced Solid Tumor sensitive detail...
Unknown unknown PF-03814735 Advanced Solid Tumor not applicable detail...
Unknown unknown GSK1070916 Advanced Solid Tumor not applicable detail...
MAP2K1 L115P CI-1040 Advanced Solid Tumor resistant detail...
MAP2K1 L115A CI-1040 Advanced Solid Tumor decreased response detail...
MAP2K1 F53S CI-1040 Advanced Solid Tumor sensitive detail...
MAP2K1 I103N CI-1040 Advanced Solid Tumor decreased response detail...
Unknown unknown WX-554 Advanced Solid Tumor not applicable detail...
Unknown unknown Docetaxel + Selumetinib Advanced Solid Tumor not applicable detail...
Unknown unknown Dacarbazine + Selumetinib Advanced Solid Tumor not applicable detail...
EGFR D770delinsGY Dacomitinib Advanced Solid Tumor sensitive detail...
EGFR S768_D770dup Dacomitinib Advanced Solid Tumor resistant detail...
EGFR A767_V769dup Dacomitinib Advanced Solid Tumor resistant detail...
EGFR Y764_V765insHH Dacomitinib Advanced Solid Tumor resistant detail...
EGFR D770delinsGY EGFR T790M Dacomitinib Advanced Solid Tumor resistant detail...
EGFR D770delinsGY EGFR C797S Dacomitinib Advanced Solid Tumor resistant detail...
EGFR D770delinsGY EGFR C797S Afatinib Advanced Solid Tumor sensitive detail...
EGFR D770delinsGY EGFR T790M Afatinib Advanced Solid Tumor sensitive detail...
ERBB2 Y772_A775dup ERBB2 C805S Neratinib Advanced Solid Tumor resistant detail...
ERBB2 Y772_A775dup ERBB2 C805S Dacomitinib Advanced Solid Tumor resistant detail...
ERBB2 Y772_A775dup ERBB2 C805S Afatinib Advanced Solid Tumor resistant detail...
ERBB2 M774delinsWLV ERBB2 C805S Afatinib Advanced Solid Tumor resistant detail...
ERBB2 M774delinsWLV ERBB2 C805S Neratinib Advanced Solid Tumor resistant detail...
ERBB2 M774delinsWLV ERBB2 C805S Dacomitinib Advanced Solid Tumor resistant detail...
ERBB2 M774delinsWLV Dacomitinib Advanced Solid Tumor sensitive detail...
ERBB2 G778_P780dup Dacomitinib Advanced Solid Tumor sensitive detail...
ERBB2 G778_S779insCPG Dacomitinib Advanced Solid Tumor sensitive detail...
ERBB2 G778_P780dup Neratinib Advanced Solid Tumor conflicting detail...
ERBB2 Y772_A775dup Neratinib Advanced Solid Tumor sensitive detail...
PTEN loss Everolimus Advanced Solid Tumor no benefit detail...
Unknown unknown IsoA Advanced Solid Tumor not applicable detail...
Unknown unknown Emibetuzumab Advanced Solid Tumor not applicable detail...
Unknown unknown Doxorubicin + Safingol Advanced Solid Tumor not applicable detail...
RET C634R RET V804M Vandetanib Advanced Solid Tumor resistant detail...
RET C634R RET Y806C Vandetanib Advanced Solid Tumor resistant detail...
RET C634R RET Y806E Vandetanib Advanced Solid Tumor resistant detail...
RET C634R RET Y806F Vandetanib Advanced Solid Tumor predicted - sensitive detail...
TP53 wild-type MK-8242 Advanced Solid Tumor unknown detail...
TP53 positive Serdemetan Advanced Solid Tumor sensitive detail...
Unknown unknown Golvatinib Advanced Solid Tumor not applicable detail...
Unknown unknown Mirvetuximab Soravtansine Advanced Solid Tumor not applicable detail...
Unknown unknown LY900009 Advanced Solid Tumor not applicable detail...
Unknown unknown PJ34 Advanced Solid Tumor not applicable detail...
JAK3 R172Q Tofacitinib Advanced Solid Tumor sensitive detail...
JAK3 L156P Tofacitinib Advanced Solid Tumor sensitive detail...
JAK3 E183G Tofacitinib Advanced Solid Tumor sensitive detail...
JAK3 A572V Tofacitinib Advanced Solid Tumor sensitive detail...
Unknown unknown BI 754091 Advanced Solid Tumor not applicable detail...
Unknown unknown E7046 Advanced Solid Tumor not applicable detail...
Unknown unknown SY-1365 Advanced Solid Tumor not applicable detail...
Unknown unknown GDC-0425 + Gemcitabine Advanced Solid Tumor not applicable detail...
BRAF mutant KO-947 Advanced Solid Tumor predicted - sensitive detail...
NRAS mutant KO-947 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown APN401 Advanced Solid Tumor not applicable detail...
EGFR positive AVID100 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Temozolomide + TRC102 Advanced Solid Tumor not applicable detail...
Unknown unknown MCLA-128 Advanced Solid Tumor not applicable detail...
Unknown unknown SAR566658 Advanced Solid Tumor not applicable detail...
Unknown unknown BEZ235 + Everolimus Advanced Solid Tumor no benefit detail...
BRAF mutant CC-90003 Advanced Solid Tumor no benefit detail...
NRAS mutant CC-90003 Advanced Solid Tumor no benefit detail...
EGFR positive AFM24 Advanced Solid Tumor sensitive detail...
TP53 wild-type ALRN-6924 Advanced Solid Tumor predicted - sensitive detail...
ERBB2 positive DS-8201a Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown ETC-159 Advanced Solid Tumor not applicable detail...
Unknown unknown PF-06647263 Advanced Solid Tumor not applicable detail...
Unknown unknown Atezolizumab + GDC-0919 Advanced Solid Tumor not applicable detail...
Unknown unknown PTC596 Advanced Solid Tumor not applicable detail...
Unknown unknown Paclitaxel + Taladegib Advanced Solid Tumor not applicable detail...
Unknown unknown TAS-116 Advanced Solid Tumor not applicable detail...
Unknown unknown BGB-A317 + Pamiparib Advanced Solid Tumor not applicable detail...
Unknown unknown BI 894999 Advanced Solid Tumor not applicable detail...
Unknown unknown CA-170 Advanced Solid Tumor not applicable detail...
EZH2 F120L EZH2 Y111N Tazemetostat Advanced Solid Tumor resistant detail...
Unknown unknown JS001 Advanced Solid Tumor not applicable detail...
Unknown unknown MSC2490484A Advanced Solid Tumor no benefit detail...
BRAF F247L Trametinib Advanced Solid Tumor sensitive detail...
BRAF F247L Dabrafenib Advanced Solid Tumor sensitive detail...
Unknown unknown OSI-027 Advanced Solid Tumor not applicable detail...
Unknown unknown LB-100 Advanced Solid Tumor not applicable detail...
Unknown unknown Epacadostat Advanced Solid Tumor not applicable detail...
Unknown unknown Seribantumab + XL147 Advanced Solid Tumor not applicable detail...
Unknown unknown IHSF115 Advanced Solid Tumor not applicable detail...
Unknown unknown Bendamustine + Veliparib Advanced Solid Tumor not applicable detail...
EGFR mutant N/A Advanced Solid Tumor no benefit detail...
BRAF F595L Vemurafenib Advanced Solid Tumor resistant detail...
BRAF D594N Vemurafenib Advanced Solid Tumor predicted - resistant detail...
MET Y1230H Capmatinib Advanced Solid Tumor predicted - resistant detail...
MET Y1230H Crizotinib Advanced Solid Tumor predicted - resistant detail...
MET Y1230H Cabozantinib Advanced Solid Tumor predicted - sensitive detail...
MET D1228N Cabozantinib Advanced Solid Tumor predicted - sensitive detail...
MET D1228N Capmatinib Advanced Solid Tumor predicted - resistant detail...
MET D1228N Crizotinib Advanced Solid Tumor predicted - resistant detail...
MET Y1230H Savolitinib Advanced Solid Tumor predicted - resistant detail...
MET D1228N Savolitinib Advanced Solid Tumor predicted - resistant detail...
MET Y1230H BMS-777607 Advanced Solid Tumor predicted - sensitive detail...
MET D1228N BMS-777607 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown ABC294640 Advanced Solid Tumor not applicable detail...
Unknown unknown Camrelizumab Advanced Solid Tumor not applicable detail...
MET del exon14 Glesatinib Advanced Solid Tumor sensitive detail...
MET del exon14 Capmatinib Advanced Solid Tumor sensitive detail...
MET del exon14 Crizotinib Advanced Solid Tumor sensitive detail...
MET del exon14 MET D1228N Glesatinib Advanced Solid Tumor sensitive detail...
MET del exon14 MET Y1230C Glesatinib Advanced Solid Tumor sensitive detail...
MET Y1230C Glesatinib Advanced Solid Tumor sensitive detail...
EGFR positive ABBV-221 Advanced Solid Tumor predicted - sensitive detail...
JAK3 I87T JANEX-1 Advanced Solid Tumor sensitive detail...
KIT N822I Imatinib Advanced Solid Tumor resistant detail...
KIT N822I Dasatinib Advanced Solid Tumor sensitive detail...
KIT V559D Dasatinib Advanced Solid Tumor sensitive detail...
KIT V559D Imatinib Advanced Solid Tumor sensitive detail...
KIT V560D Motesanib Advanced Solid Tumor sensitive detail...
Unknown unknown Gemcitabine + LY2780301 Advanced Solid Tumor not applicable detail...
KIT M552_V559del Motesanib Advanced Solid Tumor sensitive detail...
KIT Y823D Motesanib Advanced Solid Tumor sensitive detail...
KIT V560D KIT V654A Motesanib Advanced Solid Tumor sensitive detail...
KIT T670I KIT V560D Motesanib Advanced Solid Tumor sensitive detail...
KIT W557_K558del Nilotinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del Dasatinib Advanced Solid Tumor sensitive detail...
KIT W557_K558del KIT T670I Dasatinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT T670I Nilotinib Advanced Solid Tumor resistant detail...
KIT W557_K558del KIT T670I Sorafenib Advanced Solid Tumor sensitive detail...
KIT V560del KIT V654A Nilotinib Advanced Solid Tumor sensitive detail...
KIT D820Y KIT V559D Nilotinib Advanced Solid Tumor sensitive detail...
Unknown unknown Gemcitabine + MK-8776 Advanced Solid Tumor not applicable detail...
KIT D820Y KIT V559D Dasatinib Advanced Solid Tumor sensitive detail...
KIT D820Y KIT V559D Sorafenib Advanced Solid Tumor sensitive detail...
Unknown unknown Ibrutinib + unspecified PD-L1 antibody Advanced Solid Tumor not applicable detail...
Unknown unknown GDC-0575 + Gemcitabine Advanced Solid Tumor not applicable detail...
Unknown unknown CB-103 Advanced Solid Tumor not applicable detail...
Unknown unknown ASN003 Advanced Solid Tumor not applicable detail...
Unknown unknown TAS-120 Advanced Solid Tumor not applicable detail...
Unknown unknown KPT-9274 Advanced Solid Tumor not applicable detail...
Unknown unknown SL-801 Advanced Solid Tumor not applicable detail...
Unknown unknown RX-5902 Advanced Solid Tumor not applicable detail...
Unknown unknown ALM201 Advanced Solid Tumor not applicable detail...
Unknown unknown AMC303 Advanced Solid Tumor not applicable detail...
ERBB2 positive ZW25 Advanced Solid Tumor predicted - sensitive detail...
Unknown unknown Tasquinimod Advanced Solid Tumor no benefit detail...
Unknown unknown Pembrolizumab + Utomilumab Advanced Solid Tumor not applicable detail...
Unknown unknown Cetuximab + Lumretuzumab Advanced Solid Tumor not applicable detail...
Unknown unknown Erlotinib + Lumretuzumab Advanced Solid Tumor not applicable detail...
EGFR D770delinsGY Neratinib Advanced Solid Tumor resistant detail...
Unknown unknown TSR-042 Advanced Solid Tumor not applicable detail...
Unknown unknown Trebananib Advanced Solid Tumor not applicable detail...
Unknown unknown BTP-114 Advanced Solid Tumor not applicable detail...
Unknown unknown Carboplatin + TAK-243 Advanced Solid Tumor not applicable detail...
Unknown unknown Docetaxel + TAK-243 Advanced Solid Tumor not applicable detail...
Unknown unknown Radiotherapy + TAK-243 Advanced Solid Tumor not applicable detail...
Unknown unknown AMG 820 Advanced Solid Tumor no benefit detail...
Unknown unknown Crizotinib + Dasatinib Advanced Solid Tumor not applicable detail...
Unknown unknown BMS-986156 Advanced Solid Tumor not applicable detail...
PDGFRA D842V Avapritinib Advanced Solid Tumor sensitive detail...
PDGFRA V561D Avapritinib Advanced Solid Tumor sensitive detail...
KIT exon 17 Avapritinib Advanced Solid Tumor sensitive detail...
MET wild-type Glesatinib Advanced Solid Tumor decreased response detail...
EGFR L62R Erlotinib Advanced Solid Tumor sensitive detail...
EGFR L62R Afatinib Advanced Solid Tumor sensitive detail...
EGFR L62R Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L62R Cetuximab Advanced Solid Tumor sensitive detail...
EGFR R108K Afatinib Advanced Solid Tumor sensitive detail...
Unknown unknown Litronesib Advanced Solid Tumor not applicable detail...
EGFR R108K Osimertinib Advanced Solid Tumor sensitive detail...
EGFR R108K Cetuximab Advanced Solid Tumor sensitive detail...
EGFR A216T Gefitinib Advanced Solid Tumor sensitive detail...
EGFR A216T Erlotinib Advanced Solid Tumor sensitive detail...
EGFR A216T Afatinib Advanced Solid Tumor sensitive detail...
EGFR A216T Osimertinib Advanced Solid Tumor sensitive detail...
EGFR A216T Cetuximab Advanced Solid Tumor sensitive detail...
EGFR R222C Afatinib Advanced Solid Tumor sensitive detail...
EGFR R222C Osimertinib Advanced Solid Tumor sensitive detail...
EGFR R252C Afatinib Advanced Solid Tumor sensitive detail...
EGFR A289D Osimertinib Advanced Solid Tumor sensitive detail...
EGFR A289D Cetuximab Advanced Solid Tumor sensitive detail...
EGFR A289T Afatinib Advanced Solid Tumor sensitive detail...
EGFR A289T Osimertinib Advanced Solid Tumor sensitive detail...
EGFR A289T Cetuximab Advanced Solid Tumor sensitive detail...
EGFR A289V Afatinib Advanced Solid Tumor sensitive detail...
EGFR A289V Osimertinib Advanced Solid Tumor sensitive detail...
EGFR A289V Cetuximab Advanced Solid Tumor sensitive detail...
EGFR A289V Rociletinib Advanced Solid Tumor resistant detail...
EGFR V292L Afatinib Advanced Solid Tumor sensitive detail...
EGFR V292L Osimertinib Advanced Solid Tumor sensitive detail...
EGFR V292L Cetuximab Advanced Solid Tumor sensitive detail...
EGFR H304Y Afatinib Advanced Solid Tumor sensitive detail...
EGFR H304Y Osimertinib Advanced Solid Tumor sensitive detail...
EGFR H304Y Cetuximab Advanced Solid Tumor sensitive detail...
EGFR S306L Gefitinib Advanced Solid Tumor sensitive detail...
EGFR S306L Erlotinib Advanced Solid Tumor sensitive detail...
EGFR S306L Afatinib Advanced Solid Tumor sensitive detail...
EGFR S306L Osimertinib Advanced Solid Tumor resistant detail...
EGFR S306L Cetuximab Advanced Solid Tumor sensitive detail...
EGFR S492R Afatinib Advanced Solid Tumor sensitive detail...
EGFR S492R Osimertinib Advanced Solid Tumor sensitive detail...
EGFR S492R Rociletinib Advanced Solid Tumor resistant detail...
EGFR P596L Afatinib Advanced Solid Tumor sensitive detail...
EGFR P596L Osimertinib Advanced Solid Tumor sensitive detail...
EGFR P596L Cetuximab Advanced Solid Tumor sensitive detail...
EGFR G598V Afatinib Advanced Solid Tumor sensitive detail...
EGFR G598V Osimertinib Advanced Solid Tumor sensitive detail...
EGFR G598V Rociletinib Advanced Solid Tumor resistant detail...
EGFR G598V Cetuximab Advanced Solid Tumor sensitive detail...
EGFR L703I Afatinib Advanced Solid Tumor sensitive detail...
EGFR L703I Osimertinib Advanced Solid Tumor resistant detail...
EGFR L703I Cetuximab Advanced Solid Tumor resistant detail...
EGFR L703P Afatinib Advanced Solid Tumor sensitive detail...
EGFR L703P Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L703P Rociletinib Advanced Solid Tumor resistant detail...
EGFR E709_T710delinsD Cetuximab Advanced Solid Tumor resistant detail...
EGFR E709A Gefitinib Advanced Solid Tumor resistant detail...
EGFR E709A Erlotinib Advanced Solid Tumor resistant detail...
EGFR E709A Afatinib Advanced Solid Tumor sensitive detail...
EGFR E709A Rociletinib Advanced Solid Tumor resistant detail...
EGFR E709A Cetuximab Advanced Solid Tumor sensitive detail...
EGFR E709G Gefitinib Advanced Solid Tumor resistant detail...
EGFR E709G Erlotinib Advanced Solid Tumor resistant detail...
EGFR E709G Afatinib Advanced Solid Tumor sensitive detail...
EGFR E709G Rociletinib Advanced Solid Tumor resistant detail...
EGFR E709K Cetuximab Advanced Solid Tumor sensitive detail...
EGFR E709V Afatinib Advanced Solid Tumor sensitive detail...
EGFR E709V Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E709V Rociletinib Advanced Solid Tumor resistant detail...
EGFR E709V Cetuximab Advanced Solid Tumor sensitive detail...
EGFR K714R Afatinib Advanced Solid Tumor sensitive detail...
EGFR K714R Cetuximab Advanced Solid Tumor sensitive detail...
EGFR L718Q Erlotinib Advanced Solid Tumor resistant detail...
EGFR L718Q Osimertinib Advanced Solid Tumor resistant detail...
EGFR L718Q Cetuximab Advanced Solid Tumor sensitive detail...
EGFR G719A Cetuximab Advanced Solid Tumor resistant detail...
EGFR G719C Osimertinib Advanced Solid Tumor sensitive detail...
EGFR G719C Cetuximab Advanced Solid Tumor resistant detail...
EGFR G719S Osimertinib Advanced Solid Tumor sensitive detail...
EGFR G719S Cetuximab Advanced Solid Tumor resistant detail...
EGFR S720F Gefitinib Advanced Solid Tumor sensitive detail...
EGFR S720F Erlotinib Advanced Solid Tumor sensitive detail...
EGFR S720F Afatinib Advanced Solid Tumor sensitive detail...
EGFR S720F Osimertinib Advanced Solid Tumor sensitive detail...
EGFR S720F Rociletinib Advanced Solid Tumor resistant detail...
EGFR S720F Cetuximab Advanced Solid Tumor sensitive detail...
EGFR G735S Afatinib Advanced Solid Tumor sensitive detail...
EGFR G735S Osimertinib Advanced Solid Tumor sensitive detail...
EGFR G735S Cetuximab Advanced Solid Tumor resistant detail...
EGFR P741L Afatinib Advanced Solid Tumor sensitive detail...
EGFR P741L Osimertinib Advanced Solid Tumor sensitive detail...
EGFR P741L Rociletinib Advanced Solid Tumor resistant detail...
EGFR I744M Afatinib Advanced Solid Tumor sensitive detail...
EGFR I744M Cetuximab Advanced Solid Tumor resistant detail...
EGFR K745_E746insVPVAIK Afatinib Advanced Solid Tumor sensitive detail...
EGFR K745_E746insVPVAIK Osimertinib Advanced Solid Tumor sensitive detail...
EGFR K745_E746insVPVAIK Cetuximab Advanced Solid Tumor resistant detail...
EGFR E746_S752delinsV Gefitinib Advanced Solid Tumor sensitive detail...
EGFR E746_S752delinsV Erlotinib Advanced Solid Tumor sensitive detail...
EGFR E746_S752delinsV Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_S752delinsV Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_S752delinsV Cetuximab Advanced Solid Tumor resistant detail...
EGFR E746_A750delinsIP Gefitinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750delinsIP Erlotinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750delinsIP Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750delinsIP Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750delinsIP Rociletinib Advanced Solid Tumor sensitive detail...
EGFR E746_A750delinsIP Cetuximab Advanced Solid Tumor resistant detail...
EGFR E746_P753delinsVS Gefitinib Advanced Solid Tumor sensitive detail...
EGFR E746_P753delinsVS Erlotinib Advanced Solid Tumor sensitive detail...
EGFR E746_P753delinsVS Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_P753delinsVS Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_P753delinsVS Rociletinib Advanced Solid Tumor sensitive detail...
EGFR E746_P753delinsVS Cetuximab Advanced Solid Tumor resistant detail...
EGFR E746_T751delinsV Gefitinib Advanced Solid Tumor sensitive detail...
EGFR E746_T751delinsV Erlotinib Advanced Solid Tumor sensitive detail...
EGFR E746_T751delinsV Afatinib Advanced Solid Tumor sensitive detail...
EGFR E746_T751delinsV Osimertinib Advanced Solid Tumor sensitive detail...
EGFR E746_T751delinsV Cetuximab Advanced Solid Tumor resistant detail...
EGFR L747_A750delinsP Erlotinib Advanced Solid Tumor sensitive detail...
EGFR L747_A750delinsP Afatinib Advanced Solid Tumor sensitive detail...
EGFR L747_A750delinsP Osimertinib Advanced Solid Tumor sensitive detail...
EGFR L747_A750delinsP Rociletinib Advanced Solid Tumor sensitive detail...
EGFR L747_A750delinsP Cetuximab Advanced Solid Tumor resistant detail...
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