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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|SGN1||SGN-1|SGN 1|SalMet-Vec||SGN1 is a strain of Salmonella enterica engineered to harbor mutations in the MSBB and PURI genes and to express L-methioninase, which potentially reduces tumor methionine levels and inhibits umor growth (PMID: 36077761, NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT05103345||Phase I||SGN1||Study of SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumor||Recruiting||USA||1|
|NCT05038150||Phase I||SGN1||Study of SGN1 in Patients With Advanced Solid Tumor||Recruiting||USA||1|