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Molecular Profile | ALK F1174L |
Therapy | CCC-003 |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
ALK F1174L | Advanced Solid Tumor | sensitive | CCC-003 | Preclinical - Cell culture | Actionable | In a preclinical study, CCC-003 inhibited viability in transformed cells expressing ALK F1174L in culture (PMID: 34591871). | 34591871 |
PubMed Id | Reference Title | Details |
---|---|---|
(34591871) | Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides. | Full reference... |