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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|RO7198457||RG6180||RO7198457 is a personalized mRNA based cancer vaccine that stimulates T-cell mediated immune response against tumor cells (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT03289962||Phase I||RO7198457 Atezolizumab + RO7198457||A Study of RO7198457 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors||Recruiting||USA | CAN||6|
|NCT04486378||Phase II||RO7198457||A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer||Recruiting||USA||1|