Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Therapy Name | AB-16B5 |
Synonyms | |
Therapy Description |
AB-16B5 is a monoclonal antibody bonds to and inhibits the activity of human clusterin (sCLU), resulting in inhibition pf tumor cell proliferation and metastasis (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
AB-16B5 | AB-16B5 is a monoclonal antibody that binds to and inhibits the activity of human clusterin (sCLU), resulting in inhibition of tumor cell proliferation and metastasis (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT02412462 | Phase I | AB-16B5 | Phase I Dose Escalation Study of AB-16B5 in Subjects With an Advanced Solid Malignancy | Completed | CAN | 0 |