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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|CLR 131||CLR 1404 I-131||CLR 131 is a compound that contains specific phospholipid ethers, CLR 1404, linked to the radioisotope iodine I 131, which when taken up by cancer cells induces cytotoxicity (PMID: 32483729).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|
|NCT04105543||Phase I||CLR 131||CLR 131 Combined With Radiation for Head and Neck Cancer||Active, not recruiting||USA||0|
|NCT03478462||Phase I||CLR 131||Dose Escalation Study of CLR 131 in Children and Adolescents With Relapsed or Refractory Malignant Brain Cancer, Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma||Recruiting||USA | CAN||1|
|NCT05610891||Phase I||CLR 131||Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG||Not yet recruiting||USA||0|