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Therapy Name VSV-hIFNbeta-NIS
Synonyms
Therapy Description

VSV-hIFNbeta-NIS is oncolytic vesticular stomatitis virus engineered to express human interferon-beta (hIFN-beta) and sodium iodide symporter (NIS), which may inhibit tumor growth (PMID: 26712908, PMID: 22425894).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
VSV-hIFNbeta-NIS Voyager-V1|VV1 VSV-hIFNbeta-NIS is oncolytic vesticular stomatitis virus engineered to express human interferon-beta (hIFN-beta) and sodium iodide symporter (NIS), which may inhibit tumor growth (PMID: 26712908, PMID: 22425894).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03120624 Phase I VSV-hIFNbeta-NIS VSV-hIFNbeta-NIS in Treating Patients With Stage IV or Recurrent Endometrial Cancer Active, not recruiting USA 0
NCT02923466 Phase Ib/II Avelumab + VSV-hIFNbeta-NIS VSV-hIFNbeta-NIS Trial of Intratumoral Administration of Recombinant Vesicular Stomatitis Virus Monotherapy and in Combination With Avelumab in Patients With Refractory Solid Tumors Completed USA 0
NCT03017820 Phase I VSV-hIFNbeta-NIS VSV-hIFNbeta-NIS in Treating Patients With Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia, or T-cell Lymphoma Recruiting USA 0


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