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Therapy Name STI-6129
Synonyms
Therapy Description

STI-6129 is an antibody-drug conjugate (ADC) comprising an antibody against CD38 linked to the microtubule inhibitor duostatin-5.2, which may result in cytotoxic effects in CD38-expressing tumor cells and antitumor activity (Cancer Res 2020;80(16 Suppl):Abstract nr LB-227).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
STI-6129 STI 6129|STI6129 CD38 Antibody 20 STI-6129 is an antibody-drug conjugate (ADC) comprising an antibody against CD38 linked to the microtubule inhibitor duostatin-5.2, which may result in cytotoxic effects in CD38-expressing tumor cells and antitumor activity (Cancer Res 2020;80(16 Suppl):Abstract nr LB-227).

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05308225 Phase Ib/II STI-6129 Study to Assess Anti-CD38 Antibody Drug Conjugate in Relapsed or Refractory Multiple Myeloma Active, not recruiting USA 0
NCT05584709 Phase I STI-6129 Study to Access Anti-CD38 Anibody Drug in Patients With Advanced Solid Tumors Not yet recruiting USA 0
NCT05519527 Phase I STI-6129 A Phase 1, Open-Label, Dose-Escalation Study of Safety And Efficacy of An Anti-CD38 Antibody Drug Conjugate (STI-6129) In Patients With Relapsed Or Refractory T-Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) Or Acute Myeloid Leukemia (AML) Withdrawn 0


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