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Therapy Name | HRS-1167 + M1774 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
HRS-1167 | M-9466|M 9466|HRS1167|HRS 1167|M9466 | PARP-1 Inhibitor 9 | HRS-1167 inhibits PARP1, which potentially reduces tumor growth (J Clin Oncol 42, 2024 (suppl 16; abstr 3154)). | |
M1774 | M-1774|M 1774|tuvusertib | ATR Inhibitor 16 | M1774 inhibits ATR, potentially resulting in decreased tumor growth (PMID: 38407317). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT06421935 | Phase I | HRS-1167 + M1774 HRS-1167 | M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501) | Recruiting | USA | 0 |