Drug Detail


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Drug Name M1774
Trade Name
Synonyms M-1774|M 1774|tuvusertib
Drug Descriptions

M1774 inhibits ATR, potentially resulting in decreased tumor growth (PMID: 38407317).

DrugClasses ATR Inhibitor 16
CAS Registry Number 674783-97-2
NCIT ID C171067


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + M1774 Avelumab M1774 0 2
Cemiplimab + M1774 Cemiplimab M1774 0 1
Fulvestrant + M1774 Fulvestrant M1774 0 1
HRS-1167 + M1774 HRS-1167 M1774 0 1
M1774 M1774 3 4
M1774 + M4076 M1774 M4076 0 1
M1774 + Niraparib M1774 Niraparib 0 2
M1774 + Peposertib M1774 Peposertib 0 1
M1774 + PLX038 M1774 PLX038 0 1
M1774 + Temozolomide M1774 Temozolomide 0 1
M1774 + ZEN-3694 M1774 ZEN-3694 0 1

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