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Drug Name Temozolomide
Trade Name Temodar
Synonyms Methazolastone|TMZ
Drug Descriptions

Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary).

DrugClasses Chemotherapy - Alkylating 15
CAS Registry Number 85622-93-1
NCIT ID C1244

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Irinotecan + Temozolomide Abemaciclib Irinotecan Temozolomide 0 1
Abemaciclib + Temozolomide Abemaciclib Temozolomide 0 2
Acetazolamide + Temozolomide Acetazolamide Temozolomide 0 1
Adavosertib + Temozolomide Adavosertib Temozolomide 0 1
Ado-trastuzumab emtansine + Temozolomide Ado-trastuzumab emtansine Temozolomide 0 1
Alisertib + Irinotecan + Temozolomide Alisertib Irinotecan Temozolomide 0 1
Atezolizumab + Irinotecan + Temozolomide + Vincristine Sulfate Atezolizumab Irinotecan Temozolomide Vincristine Sulfate 0 1
Atezolizumab + Temozolomide Atezolizumab Temozolomide 0 2
Autologous CMV-specific CTLs + Temozolomide Autologous CMV-specific CTLs Temozolomide 0 1
AZ64 + Irinotecan + Temozolomide AZ64 Irinotecan Temozolomide 0 0
AZD2461 + Temozolomide AZD2461 Temozolomide 0 0
AZD5991 + Temozolomide AZD5991 Temozolomide 1 0
Bavituximab + Temozolomide Bavituximab Temozolomide 0 1
Bevacizumab + Bortezomib + Temozolomide Bevacizumab Bortezomib Temozolomide 0 1
Bevacizumab + Capecitabine + Temozolomide Bevacizumab Capecitabine Temozolomide 0 2
Bevacizumab + Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Irinotecan + Sorafenib + Temozolomide + Temsirolimus + Vincristine Sulfate Bevacizumab Cyclophosphamide Doxorubicin Etoposide Ifosfamide Irinotecan Sorafenib Temozolomide Temsirolimus Vincristine Sulfate 0 1
Bevacizumab + Erlotinib + Temozolomide Bevacizumab Erlotinib Temozolomide 0 1
Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + Temozolomide Bevacizumab Fluorouracil Irinotecan Leucovorin Temozolomide 0 1
Bevacizumab + Irinotecan + SGT-53 + Temozolomide Bevacizumab Irinotecan SGT-53 Temozolomide 0 1
Bevacizumab + Irinotecan + Temozolomide Bevacizumab Irinotecan Temozolomide 0 4
Bevacizumab + Nab-paclitaxel + Temozolomide Bevacizumab Nab-paclitaxel Temozolomide 0 1
Bevacizumab + Temozolomide Bevacizumab Temozolomide 0 8
Bevacizumab + Temozolomide + Topotecan Bevacizumab Temozolomide Topotecan 0 1
BMS-986205 + Nivolumab + Temozolomide BMS-986205 Nivolumab Temozolomide 0 1
BMX-001 + Temozolomide BMX-001 Temozolomide 0 1
Bortezomib + Temozolomide Bortezomib Temozolomide 0 1
BPM 31510 + Temozolomide BPM 31510 Temozolomide 0 1
Buparlisib + Temozolomide Buparlisib Temozolomide 0 1
Cabozantinib + Temozolomide Cabozantinib Temozolomide 0 2
Cannabidiol + Temozolomide Cannabidiol Temozolomide 0 1
Capecitabine + Temozolomide + Veliparib Capecitabine Temozolomide Veliparib 0 1
Carboplatin + Mebendazole + Temozolomide + Vincristine Sulfate Carboplatin Mebendazole Temozolomide Vincristine Sulfate 0 1
Carboxyamidotriazole Orotate + Temozolomide Carboxyamidotriazole Orotate Temozolomide 0 1
Carmustine + Filgrastim + O6-benzylguanine + Temozolomide Carmustine Filgrastim O6-benzylguanine Temozolomide 0 1
Carmustine + Filgrastim + Plerixafor + Temozolomide Carmustine Filgrastim Plerixafor Temozolomide 0 1
CC-90010 + Temozolomide CC-90010 Temozolomide 0 1
Cefixime + Irinotecan + Temozolomide + Vincristine Sulfate Cefixime Irinotecan Temozolomide Vincristine Sulfate 0 1
Cefixime + Irinotecan + Temozolomide + Vincristine Sulfate + Vorinostat Cefixime Irinotecan Temozolomide Vincristine Sulfate Vorinostat 0 1
Cemiplimab + INO-5401 + INO-9012 + Temozolomide Cemiplimab INO-5401 INO-9012 Temozolomide 0 1
CEP-9722 + Temozolomide CEP-9722 Temozolomide 0 0
Cisplatin + Nivolumab + Temozolomide Cisplatin Nivolumab Temozolomide 0 1
Cytarabine + Dexamethasone + Etoposide + Ibrutinib + Isavuconazole + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Cytarabine Dexamethasone Etoposide Ibrutinib Isavuconazole Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 1
Cytarabine + Dexamethasone + Etoposide + Isavuconazole + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Cytarabine Dexamethasone Etoposide Isavuconazole Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 1
Dasatinib + Irinotecan + Nab-Rapamycin + Temozolomide Dasatinib Irinotecan Nab-Rapamycin Temozolomide 0 0
Dasatinib + Irinotecan + Sirolimus + Temozolomide Dasatinib Irinotecan Sirolimus Temozolomide 0 1
Decitabine + Panobinostat + Temozolomide Decitabine Panobinostat Temozolomide 0 1
Depatuxizumab mafodotin + Radiotherapy + Temozolomide Depatuxizumab mafodotin Radiotherapy Temozolomide 0 0
Depatuxizumab mafodotin + Temozolomide Depatuxizumab mafodotin Temozolomide 0 1
Dexamethasone + Etoposide + Ibrutinib + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Dexamethasone Etoposide Ibrutinib Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 0
Dexamethasone + Etoposide + Ibrutinib + Pegylated liposomal-doxorubicin + Temozolomide Dexamethasone Etoposide Ibrutinib Pegylated liposomal-doxorubicin Temozolomide 0 1
Dexamethasone + Etoposide + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Dexamethasone Etoposide Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 0
Dinutuximab + Irinotecan + Isotretinoin + Sargramostim + Temozolomide Dinutuximab Irinotecan Isotretinoin Sargramostim Temozolomide 0 1
Dinutuximab beta + Temozolomide Dinutuximab beta Temozolomide 0 1
Dinutuximab beta + Temozolomide + Topotecan Dinutuximab beta Temozolomide Topotecan 0 1
E7016 + Temozolomide E7016 Temozolomide 0 0
E7449 + Temozolomide E7449 Temozolomide 0 0
Entinostat + Temozolomide Entinostat Temozolomide 0 0
Enzastaurin + Temozolomide Enzastaurin Temozolomide 0 1
Erlotinib + Temozolomide Erlotinib Temozolomide 0 1
Etoposide + Temozolomide Etoposide Temozolomide 0 1
FANG vaccine + Irinotecan + Temozolomide FANG vaccine Irinotecan Temozolomide 0 2
Fluzoparib + Temozolomide Fluzoparib Temozolomide 0 0
Glasdegib + Temozolomide Glasdegib Temozolomide 0 1
GNF-4256 + Irinotecan + Temozolomide GNF-4256 Irinotecan Temozolomide 0 0
Ibrutinib + Temozolomide Ibrutinib Temozolomide 0 1
Ibudilast + Temozolomide Ibudilast Temozolomide 0 1
IGV-001 + Temozolomide IGV-001 Temozolomide 0 1
Indoximod + Lomustine + Temozolomide Indoximod Lomustine Temozolomide 0 1
Indoximod + Temozolomide Indoximod Temozolomide 0 1
Iniparib + Radiotherapy + Temozolomide Iniparib Radiotherapy Temozolomide 0 0
Ipilimumab + Nivolumab + Temozolomide Ipilimumab Nivolumab Temozolomide 0 1
Irinotecan + MLN4924 + Temozolomide Irinotecan MLN4924 Temozolomide 0 1
Irinotecan + Nab-Rapamycin + Temozolomide Irinotecan Nab-Rapamycin Temozolomide 0 1
Irinotecan + Naxitamab + Sargramostim + Temozolomide Irinotecan Naxitamab Sargramostim Temozolomide 0 2
Irinotecan + Palbociclib + Temozolomide Irinotecan Palbociclib Temozolomide 0 1
Irinotecan + Pazopanib + Temozolomide Irinotecan Pazopanib Temozolomide 0 1
Irinotecan + Prexasertib + Temozolomide Irinotecan Prexasertib Temozolomide 0 1
Irinotecan + Repotrectinib + Temozolomide Irinotecan Repotrectinib Temozolomide 0 1
Irinotecan + RRx-001 + Temozolomide Irinotecan RRx-001 Temozolomide 0 1
Irinotecan + Sirolimus + Sunitinib + Temozolomide Irinotecan Sirolimus Sunitinib Temozolomide 0 0
Irinotecan + Temozolomide Irinotecan Temozolomide 0 5
Irinotecan + Temozolomide + Vincristine Sulfate Irinotecan Temozolomide Vincristine Sulfate 0 1
Lapatinib + Temozolomide Lapatinib Temozolomide 0 1
Lorlatinib + Temozolomide Lorlatinib Temozolomide 0 1
M7824 + Temozolomide M7824 Temozolomide 0 1
Mefloquine + Memantine + Metformin + Temozolomide Mefloquine Memantine Metformin Temozolomide 0 1
Mefloquine + Memantine + Temozolomide Mefloquine Memantine Temozolomide 0 1
Mefloquine + Metformin + Temozolomide Mefloquine Metformin Temozolomide 0 1
Mefloquine + Temozolomide Mefloquine Temozolomide 0 1
Memantine + Metformin + Temozolomide Memantine Metformin Temozolomide 0 1
Memantine + Temozolomide Memantine Temozolomide 0 1
Metformin + Temozolomide Metformin Temozolomide 0 2
Montanide ISA 51 + PEPIDH1M vaccine + Sargramostim + Temozolomide Montanide ISA 51 PEPIDH1M vaccine Sargramostim Temozolomide 0 1
Nab-paclitaxel + Oblimersen + Temozolomide Nab-paclitaxel Oblimersen Temozolomide 0 0
Nab-Rapamycin + Temozolomide Nab-Rapamycin Temozolomide 0 1
NeoVax + Pembrolizumab + Temozolomide NeoVax Pembrolizumab Temozolomide 0 1
Neratinib + Temozolomide Neratinib Temozolomide 0 1
NG101m + Temozolomide NG101m Temozolomide 0 1
Niraparib + Temozolomide Niraparib Temozolomide 0 2
Nivolumab + Temozolomide Nivolumab Temozolomide 0 4
NMS-03305293 + Temozolomide NMS-03305293 Temozolomide 0 1
NMS-P118 + Temozolomide NMS-P118 Temozolomide 0 0
NSC124854 + Temozolomide NSC124854 Temozolomide 0 0
NSC666715 + Temozolomide NSC666715 Temozolomide 0 0
NT-I7 + Radiotherapy + Temozolomide NT-I7 Radiotherapy Temozolomide 0 1
NU6027 + Temozolomide NU6027 Temozolomide 1 0
O6-benzylguanine + Temozolomide O6-benzylguanine Temozolomide 0 1
OKN-007 + Temozolomide OKN-007 Temozolomide 0 2
Olaparib + Pamiparib + Temozolomide Olaparib Pamiparib Temozolomide 0 1
Olaparib + SN-38 + Temozolomide Olaparib SN-38 Temozolomide 0 0
Olaparib + Temozolomide Olaparib Temozolomide 0 5
Osimertinib + Temozolomide Osimertinib Temozolomide 0 1
PAC-1 + Temozolomide PAC-1 Temozolomide 0 1
Pamiparib + Temozolomide Pamiparib Temozolomide 0 6
Pazopanib + Temozolomide Pazopanib Temozolomide 0 1
Pembrolizumab + Radiotherapy + Temozolomide Pembrolizumab Radiotherapy Temozolomide 0 0
Pembrolizumab + Temozolomide Pembrolizumab Temozolomide 0 3
Pembrolizumab + Temozolomide + Vitespen Pembrolizumab Temozolomide Vitespen 0 1
Pembrolizumab + Temozolomide + Vorinostat Pembrolizumab Temozolomide Vorinostat 0 1
PEPIDH1M vaccine + Temozolomide PEPIDH1M vaccine Temozolomide 0 0
Plerixafor + Temozolomide Plerixafor Temozolomide 0 1
pp65 Dendritic Cell Vaccine + Temozolomide Temozolomide pp65 Dendritic Cell Vaccine 0 2
pp65 Dendritic Cell Vaccine + Temozolomide + Varlilumab Temozolomide Varlilumab pp65 Dendritic Cell Vaccine 0 1
Radiotherapy + RO4929097 + Temozolomide RO4929097 Radiotherapy Temozolomide 0 0
Radiotherapy + Telaglenastat + Temozolomide Radiotherapy Telaglenastat Temozolomide 0 1
Radiotherapy + Temozolomide Radiotherapy Temozolomide 0 1
Radiotherapy + Temozolomide + Veliparib Radiotherapy Temozolomide Veliparib 0 0
Ribociclib + Temozolomide + Topotecan Ribociclib Temozolomide Topotecan 0 1
RRx-001 + Temozolomide RRx-001 Temozolomide 0 1
Rucaparib + Temozolomide Rucaparib Temozolomide 0 0
Ruxolitinib + Temozolomide Ruxolitinib Temozolomide 0 1
Selinexor + Temozolomide Selinexor Temozolomide 0 2
SEN-450 + Temozolomide SEN-450 Temozolomide 0 0
SLC-0111 + Temozolomide SLC-0111 Temozolomide 0 0
STA-8666 + Temozolomide + Vincristine Sulfate STA-8666 Temozolomide Vincristine Sulfate 0 1
Sunitinib + Temozolomide Sunitinib Temozolomide 0 1
Talazoparib + Temozolomide Talazoparib Temozolomide 0 4
Temozolomide Temozolomide 1 48
Temozolomide + Topotecan Temozolomide Topotecan 0 1
Temozolomide + TRC102 TRC102 Temozolomide 0 1
Temozolomide + UMI-77 Temozolomide UMI-77 1 0
Temozolomide + Valproic acid Temozolomide Valproic acid 0 0
Temozolomide + Vandetanib Temozolomide Vandetanib 2 0
Temozolomide + Veliparib Temozolomide Veliparib 3 3
Temozolomide + Vistusertib Temozolomide Vistusertib 0 0
Temozolomide + Zotiraciclib Temozolomide Zotiraciclib 0 2


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