Drug Detail

Drug Name Temozolomide
Trade Name Temodar
Synonyms Methazolastone
Drug Descriptions

Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary).

DrugClasses Chemotherapy - Alkylating 14

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Temozolomide Abemaciclib Temozolomide 0 1
Adavosertib + Temozolomide Adavosertib Temozolomide 0 1
Ado-trastuzumab emtansine + Temozolomide Ado-trastuzumab emtansine Temozolomide 0 1
Alisertib + Irinotecan + Temozolomide Alisertib Irinotecan Temozolomide 2 1
Atezolizumab + Temozolomide Atezolizumab Temozolomide 0 1
AZ64 + Irinotecan + Temozolomide AZ64 Irinotecan Temozolomide 0 0
AZD2461 + Temozolomide AZD2461 Temozolomide 1 0
Bavituximab + Temozolomide Bavituximab Temozolomide 0 1
Bevacizumab + Bortezomib + Temozolomide Bevacizumab Bortezomib Temozolomide 0 1
Bevacizumab + Capecitabine + Temozolomide Bevacizumab Capecitabine Temozolomide 0 1
Bevacizumab + Cyclophosphamide + Doxorubicin + Etoposide + Ifosfamide + Irinotecan + Sorafenib + Temozolomide + Temsirolimus + Vincristine Bevacizumab Cyclophosphamide Doxorubicin Etoposide Ifosfamide Irinotecan Sorafenib Temozolomide Temsirolimus Vincristine 0 1
Bevacizumab + Erlotinib + Temozolomide Bevacizumab Erlotinib Temozolomide 0 1
Bevacizumab + Irinotecan + SGT-53 + Temozolomide Bevacizumab Irinotecan SGT-53 Temozolomide 0 1
Bevacizumab + Irinotecan + Temozolomide Bevacizumab Irinotecan Temozolomide 1 3
Bevacizumab + Nab-paclitaxel + Temozolomide Bevacizumab Nab-paclitaxel Temozolomide 0 1
Bevacizumab + Temozolomide Bevacizumab Temozolomide 0 7
BMX-001 + Temozolomide BMX-001 Temozolomide 0 1
Bortezomib + Temozolomide Bortezomib Temozolomide 0 1
Buparlisib + Temozolomide Buparlisib Temozolomide 0 1
Cannabidiol + Temozolomide Cannabidiol Temozolomide 0 1
Capecitabine + Temozolomide + Veliparib Capecitabine Temozolomide Veliparib 0 1
Carboplatin + Mebendazole + Temozolomide + Vincristine Carboplatin Mebendazole Temozolomide Vincristine 0 1
Carboxyamidotriazole Orotate + Temozolomide Carboxyamidotriazole Orotate Temozolomide 0 1
Carmustine + Filgrastim + Plerixafor + Temozolomide Carmustine Filgrastim Plerixafor Temozolomide 0 1
Cemiplimab + INO-5401 + INO-9012 + Temozolomide Cemiplimab INO-5401 INO-9012 Temozolomide 0 1
CEP-9722 + Temozolomide CEP-9722 Temozolomide 0 0
Cytarabine + Dexamethasone + Etoposide + Ibrutinib + Isavuconazole + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Cytarabine Dexamethasone Etoposide Ibrutinib Isavuconazole Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 1
Cytarabine + Dexamethasone + Etoposide + Isavuconazole + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Cytarabine Dexamethasone Etoposide Isavuconazole Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 1
Decitabine + Panobinostat + Temozolomide Decitabine Panobinostat Temozolomide 0 1
Depatuxizumab mafodotin + Radiotherapy + Temozolomide Depatuxizumab mafodotin Radiotherapy Temozolomide 1 0
Dexamethasone + Etoposide + Ibrutinib + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Dexamethasone Etoposide Ibrutinib Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 0
Dexamethasone + Etoposide + Ibrutinib + Pegylated liposomal-doxorubicin + Temozolomide Dexamethasone Etoposide Ibrutinib Pegylated liposomal-doxorubicin Temozolomide 0 1
Dexamethasone + Etoposide + Pegylated liposomal-doxorubicin + Rituximab + Temozolomide Dexamethasone Etoposide Pegylated liposomal-doxorubicin Rituximab Temozolomide 0 0
E7016 + Temozolomide E7016 Temozolomide 0 0
E7449 + Temozolomide E7449 Temozolomide 1 0
Entinostat + Temozolomide Entinostat Temozolomide 0 0
Erlotinib + Temozolomide Erlotinib Temozolomide 0 1
Etoposide + Temozolomide Etoposide Temozolomide 0 1
FANG vaccine + Irinotecan + Temozolomide FANG vaccine Irinotecan Temozolomide 0 1
GNF-4256 + Irinotecan + Temozolomide GNF-4256 Irinotecan Temozolomide 0 0
Ibrutinib + Temozolomide Ibrutinib Temozolomide 0 1
Ibudilast + Temozolomide Ibudilast Temozolomide 0 1
Iniparib + Radiotherapy + Temozolomide Iniparib Radiotherapy Temozolomide 1 0
Irinotecan + MLN4924 + Temozolomide Irinotecan MLN4924 Temozolomide 0 1
Irinotecan + Nab-Rapamycin + Temozolomide Irinotecan Nab-Rapamycin Temozolomide 0 1
Irinotecan + Naxitamab + Sargramostim + Temozolomide Irinotecan Naxitamab Sargramostim Temozolomide 0 1
Irinotecan + Palbociclib + Temozolomide Irinotecan Palbociclib Temozolomide 0 1
Irinotecan + Pazopanib + Temozolomide Irinotecan Pazopanib Temozolomide 0 1
Irinotecan + Sirolimus + Sunitinib + Temozolomide Irinotecan Sirolimus Sunitinib Temozolomide 1 0
Irinotecan + Temozolomide Irinotecan Temozolomide 0 3
Irinotecan + Temozolomide + Vincristine Irinotecan Temozolomide Vincristine 0 1
Lapatinib + Temozolomide Lapatinib Temozolomide 0 1
M7824 + Temozolomide M7824 Temozolomide 0 1
Nab-paclitaxel + Oblimersen + Temozolomide Nab-paclitaxel Oblimersen Temozolomide 1 0
Nab-Rapamycin + Temozolomide Nab-Rapamycin Temozolomide 0 1
Neratinib + Temozolomide Neratinib Temozolomide 0 1
Niraparib + Temozolomide Niraparib Temozolomide 1 2
Nivolumab + Temozolomide Nivolumab Temozolomide 0 2
NMS-P118 + Temozolomide NMS-P118 Temozolomide 0 0
NSC124854 + Temozolomide NSC124854 Temozolomide 0 0
NSC666715 + Temozolomide NSC666715 Temozolomide 0 0
NU6027 + Temozolomide NU6027 Temozolomide 1 0
O6-benzylguanine + Temozolomide O6-benzylguanine Temozolomide 0 1
Olaparib + SN-38 + Temozolomide Olaparib SN-38 Temozolomide 1 0
Olaparib + Temozolomide Olaparib Temozolomide 3 1
PAC-1 + Temozolomide PAC-1 Temozolomide 0 1
Pamiparib + Temozolomide Pamiparib Temozolomide 0 4
Pazopanib + Temozolomide Pazopanib Temozolomide 0 1
Pembrolizumab + Radiotherapy + Temozolomide Pembrolizumab Radiotherapy Temozolomide 0 0
Pembrolizumab + Temozolomide Pembrolizumab Temozolomide 0 3
Pembrolizumab + Temozolomide + Vitespen Pembrolizumab Temozolomide Vitespen 0 1
Pembrolizumab + Temozolomide + Vorinostat Pembrolizumab Temozolomide Vorinostat 0 1
Plerixafor + Temozolomide Plerixafor Temozolomide 0 1
pp65 Dendritic Cell Vaccine + Temozolomide Temozolomide pp65 Dendritic Cell Vaccine 0 2
pp65 Dendritic Cell Vaccine + Temozolomide + Varlilumab Temozolomide Varlilumab pp65 Dendritic Cell Vaccine 0 1
Radiotherapy + RO4929097 + Temozolomide RO4929097 Radiotherapy Temozolomide 1 0
RRx-001 + Temozolomide RRx-001 Temozolomide 0 1
Rucaparib + Temozolomide Rucaparib Temozolomide 1 0
Ruxolitinib + Temozolomide Ruxolitinib Temozolomide 0 1
SEN-450 + Temozolomide SEN-450 Temozolomide 1 0
SLC-0111 + Temozolomide SLC-0111 Temozolomide 0 0
Sunitinib + Temozolomide Sunitinib Temozolomide 0 1
Talazoparib + Temozolomide Talazoparib Temozolomide 1 3
Temozolomide Temozolomide 1 37
Temozolomide + TG02 TG02 Temozolomide 0 1
Temozolomide + TRC102 TRC102 Temozolomide 1 0
Temozolomide + Valproic acid Temozolomide Valproic acid 0 0
Temozolomide + Vandetanib Temozolomide Vandetanib 4 0
Temozolomide + Veliparib Temozolomide Veliparib 1 3


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