Drug Detail


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Drug Name Pamiparib
Trade Name
Synonyms BGB-290|BGB290
Drug Descriptions

Pamiparib (BGB-290) inhibits PARP1 and PARP2, potentially resulting in increased sensitivity to DNA damaging agents (AACR; 2015. Abstract nr 1651, PMID: 32652442).

DrugClasses PARP Inhibitor (Pan) 26
CAS Registry Number 1446261-44-4
NCIT ID C120553


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cabozantinib + Pamiparib Cabozantinib Pamiparib 0 1
Fluorouracil + Hydroxyurea + Pamiparib + Tislelizumab Fluorouracil Hydroxyurea Pamiparib Tislelizumab 0 1
Olaparib + Pamiparib + Temozolomide Olaparib Pamiparib Temozolomide 0 1
Pamiparib Pamiparib 0 5
Pamiparib + Temozolomide Pamiparib Temozolomide 0 6
Pamiparib + Tislelizumab Pamiparib Tislelizumab 0 3

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