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Drug Name Tislelizumab
Trade Name
Synonyms BGB-A317
Drug Descriptions

Tislelizumab (BGB-A317) is a human monoclonal antibody that targets PD-1 (PDCD1), thereby blocking the binding of PD-L1 (CD274) and potentially resulting in activation of a T-cell immune response against tumor cells (PMID: 32769013, PMID: 32561638, PMID: 32540858).

DrugClasses Immune Checkpoint Inhibitor 135 PD-L1/PD-1 antibody 79
CAS Registry Number 1858168-59-8
NCIT ID C121775

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BGB-15025 + Tislelizumab BGB-15025 Tislelizumab 0 1
BGB-A425 + Tislelizumab BGB-A425 Tislelizumab 0 1
BGBA1217 + Carboplatin + Etoposide + Tislelizumab BGBA1217 Carboplatin Etoposide Tislelizumab 0 1
BGBA1217 + Carboplatin + Nab-paclitaxel + Tislelizumab BGBA1217 Carboplatin Nab-paclitaxel Tislelizumab 0 1
BGBA1217 + Carboplatin + Paclitaxel + Tislelizumab BGBA1217 Carboplatin Paclitaxel Tislelizumab 0 1
BGBA1217 + Carboplatin + Pemetrexed Disodium + Tislelizumab BGBA1217 Carboplatin Pemetrexed Disodium Tislelizumab 0 1
BGBA1217 + Cisplatin + Etoposide + Tislelizumab BGBA1217 Cisplatin Etoposide Tislelizumab 0 1
BGBA1217 + Cisplatin + Pemetrexed Disodium + Tislelizumab BGBA1217 Cisplatin Pemetrexed Disodium Tislelizumab 0 1
BGBA1217 + Tislelizumab BGBA1217 Tislelizumab 0 4
Capecitabine + DKN-01 + Oxaliplatin + Tislelizumab Capecitabine DKN-01 Oxaliplatin Tislelizumab 0 1
Capecitabine + Oxaliplatin + Tislelizumab Capecitabine Oxaliplatin Tislelizumab 0 1
Capecitabine + Tislelizumab Capecitabine Tislelizumab 0 1
Carboplatin + Etoposide + Tislelizumab Carboplatin Etoposide Tislelizumab 0 0
Carboplatin + Gemcitabine + Tislelizumab Carboplatin Gemcitabine Tislelizumab 0 0
Carboplatin + Nab-paclitaxel + Tislelizumab Carboplatin Nab-paclitaxel Tislelizumab 0 0
Carboplatin + Paclitaxel + Tislelizumab Carboplatin Paclitaxel Tislelizumab 0 2
Carboplatin + Pemetrexed Disodium + Tislelizumab Carboplatin Pemetrexed Disodium Tislelizumab 0 0
Cisplatin + Etoposide + Tislelizumab Cisplatin Etoposide Tislelizumab 0 1
Cisplatin + Fluorouracil + Tislelizumab Cisplatin Fluorouracil Tislelizumab 0 1
Cisplatin + Gemcitabine + Tislelizumab Cisplatin Gemcitabine Tislelizumab 0 0
Cisplatin + Paclitaxel + Tislelizumab Cisplatin Paclitaxel Tislelizumab 0 0
Cisplatin + Pemetrexed Disodium + Tislelizumab Cisplatin Pemetrexed Disodium Tislelizumab 0 0
Dacarbazine + Doxorubicin + Tislelizumab + Vinblastine Dacarbazine Doxorubicin Tislelizumab Vinblastine 0 1
DKN-01 + Tislelizumab DKN-01 Tislelizumab 0 1
Fruquintinib + Tislelizumab Fruquintinib Tislelizumab 0 1
Pamiparib + Tislelizumab Pamiparib Tislelizumab 0 2
Pemetrexed Disodium + Tislelizumab Pemetrexed Disodium Tislelizumab 0 1
Surufatinib + Tislelizumab Surufatinib Tislelizumab 0 1
Tislelizumab Tislelizumab 0 12


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