Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Tislelizumab
Trade Name
Synonyms BGB-A317
Drug Descriptions

Tislelizumab (BGB-A317) is a human monoclonal antibody that targets PD-1 (PDCD1), thereby blocking the binding of PD-L1 (CD274) and potentially resulting in activation of a T-cell immune response against tumor cells (PMID: 32769013, PMID: 32561638, PMID: 32540858).

DrugClasses Immune Checkpoint Inhibitor 94 PD-L1/PD-1 antibody 63


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
BGB-A425 + Tislelizumab BGB-A425 Tislelizumab 0 1
Capecitabine + Oxaliplatin + Tislelizumab Capecitabine Oxaliplatin Tislelizumab 0 1
Capecitabine + Tislelizumab Capecitabine Tislelizumab 0 1
Carboplatin + Paclitaxel + Tislelizumab Carboplatin Paclitaxel Tislelizumab 0 1
Cisplatin + Etoposide + Tislelizumab Cisplatin Etoposide Tislelizumab 0 1
Cisplatin + Fluorouracil + Tislelizumab Cisplatin Fluorouracil Tislelizumab 0 1
Pamiparib + Tislelizumab Pamiparib Tislelizumab 4 2
Pemetrexed Disodium + Tislelizumab Pemetrexed Disodium Tislelizumab 0 1
Tislelizumab Tislelizumab 0 6

Additional content available in CKB BOOST