Drug Detail


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Drug Name Surufatinib
Trade Name
Synonyms Sulfatinib|HMPL-012
Drug Descriptions

Surufatinib (HMPL-012) is a dual VEGFR/FGFR1 inhibitor, which potentially results in reduced cell proliferation and migration, alteration of the tumor microenvironment, and inhibition of tumor angiogenesis and growth (PMID: 37361567).

DrugClasses FGFR1 Inhibitor 28 VEGFR Inhibitor (Pan) 36
CAS Registry Number 1308672-74-3
NCIT ID C116066


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Doxorubicin + Surufatinib Doxorubicin Surufatinib 0 0
Gemcitabine + Surufatinib Gemcitabine Surufatinib 0 1
Surufatinib Surufatinib 0 3
Surufatinib + Tislelizumab Surufatinib Tislelizumab 0 1
Surufatinib + Toripalimab-tpzi Surufatinib Toripalimab-tpzi 0 0

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