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| Drug Name | Toripalimab-tpzi |
| Trade Name | Loqtorz |
| Synonyms | Toripalimab|JS001|JS-001|TAB001 |
| Drug Descriptions |
Loqtorz (toripalimab-tpzi) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response and decreased tumor growth (PMID: 28317872; PMID: 32277740, PMID: 32406293, PMID: 32321714). Loqtorz (toripalimab-tpzi) in combination with cisplatin and gemcitabine is FDA-approved for use in adult patients with metastatic or recurrent, locally advanced nasopharyngeal carcinoma (FDA.gov). |
| DrugClasses | Immune Checkpoint Inhibitor 146 PD-L1/PD-1 antibody 112 |
| CAS Registry Number | 1924598-82-2 |
| NCIT ID | C131334 |
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