Drug Detail


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Drug Name Toripalimab
Trade Name
Synonyms JS001|JS-001|TAB001
Drug Descriptions

Toripalimab (JS001) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response and decreased tumor growth (PMID: 28317872; PMID: 32277740, PMID: 32406293, PMID: 32321714).

DrugClasses Immune Checkpoint Inhibitor 151 PD-L1/PD-1 antibody 98
CAS Registry Number 1924598-82-2
NCIT ID C131334


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anlotinib + Toripalimab Anlotinib Toripalimab 0 0
Bevacizumab + Capecitabine + Oxaliplatin + Toripalimab Bevacizumab Capecitabine Oxaliplatin Toripalimab 0 0
Capecitabine + Oxaliplatin + Toripalimab Capecitabine Oxaliplatin Toripalimab 0 0
Cisplatin + Docetaxel + Fluorouracil + Toripalimab Cisplatin Docetaxel Fluorouracil Toripalimab 0 0
Cisplatin + Gemcitabine + Toripalimab Cisplatin Gemcitabine Toripalimab 0 0
Cisplatin + Paclitaxel + Toripalimab Cisplatin Paclitaxel Toripalimab 0 0
Fluorouracil + Leucovorin + Oxaliplatin + Toripalimab Fluorouracil Leucovorin Oxaliplatin Toripalimab 0 0
Gemcitabine + Nab-paclitaxel + Toripalimab + YH003 Gemcitabine Nab-paclitaxel Toripalimab YH003 0 1
GFH018 + Toripalimab GFH018 Toripalimab 0 1
LBL-007 + Toripalimab LBL-007 Toripalimab 0 0
LM-061 + Toripalimab LM-061 Toripalimab 0 1
Onatasertib + Toripalimab Onatasertib Toripalimab 0 0
Toripalimab Toripalimab 4 1
Toripalimab + TPX-4589 TPX-4589 Toripalimab 0 1
Toripalimab + YH001 Toripalimab YH001 0 2
Toripalimab + YH003 Toripalimab YH003 0 1

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