Drug Detail

Drug Name Leucovorin
Trade Name Wellcovorin
Synonyms Calcium folinate|Calcium citrovorum factor|folinic acid
Drug Descriptions

Wellcovorin (leucovorin) is a metabolite of folate that enhances the efficacy of fluoruracil (NCI Drug Dictionary).

DrugClasses Chemotherapy - Antimetabolite 10

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Therapy Name Therapy Description
INCB001158 + FOLFOX
Binimetinib + FOLFIRI + Pembrolizumab
Bevacizumab + Fluorouracil + Leucovorin
Aflibercept + mFOLFOX-6
NANT colorectal cancer vaccine combination
Fluorouracil + Capecitabine + Irinotecan + Leucovorin + Oxaliplatin
Fluorouracil + Leucovorin + Regorafenib
Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin + NANT-008
Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin + Nivolumab
Bevacizumab + MEDI4736 + Tremelimumab + FOLFOX
Bevacizumab + FOLFOX + Nab-Rapamycin
Cetuximab + FOLFIRINOX
Floxuridine + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab
FOLFIRINOX + Losartan + Nivolumab
Binimetinib + Fluorouracil + Leucovorin + Oxaliplatin + Pembrolizumab
Vandetanib + FOLFOX
Leucovorin + Pegaspargase + Vincristine
FOLFIRI + Pembrolizumab
Ad-CEA + Bevacizumab + FOLFOX
Bevacizumab + FOLFIRI
Fluoruracil + Leucovorin + Prexasertib
Fluorouracil + Leucovorin
RO5520985 + Leucovorin + Fluorouracil
FOLFIRI + SYM004
Fluorouracil + Bevacizumab + Capecitabine + Leucovorin + Oxaliplatin
Cetuximab + FOLFIRI + Bevacizumab
NANT pancreatic cancer vaccine combination
Axitinib + FOLFIRI
simtuzumab + FOLFIRI
mFOLFOX-6 + Atezolizumab + Cobimetinib
Aflibercept + FOLFIRI
Cabiralizumab + Fluorouracil + Irinotecan + Leucovorin + Nivolumab
Binimetinib + FOLFIRI
Oleclumab + mFOLFOX
Fluorouracil + Leucovorin + Oxaliplatin + Pembrolizumab
Fluorouracil + Leucovorin + Trastuzumab
FOLFIRINOX + Nivolumab
AB928 + mFOLFOX-6
Leucovorin Wellcovorin (leucovorin) is a metabolite of folate that enhances the efficacy of fluoruracil (NCI Drug Dictionary).
CPI-613 + FOLFIRINOX
Nivolumab + mFOLFOX-6
FABLOx
Bevacizumab + Atezolizumab + Fluorouracil + Leucovorin + Oxaliplatin
mFOLFOX-6 + Pegilodecakin
Cetuximab + FOLFOX
Onartuzumab + mFOLFOX6
Cetuximab + Dasatinib + FOLFOX
NANT hepatocellular carcinoma vaccine combination
Ramucirumab + FOLFOX
Cytarabine + Fludarabine + Leucovorin + Panobinostat
mFOLFOX-6 + Tivozanib
Bevacizumab + Cannabidiol + FOLFIRINOX
FPA144 + Fluorouracil + Leucovorin + Oxaliplatin
Erlotinib + Fluorouracil + Leucovorin + nab-paclitaxel + Trastuzumab
Axitinib + FOLFOX
Durvalumab + Oleclumab + mFOLFOX
MEK162 + FOLFOX
Claudiximab + FOLFOX
CV301 + Nivolumab + mFOLFOX6
Lapatinib + Oxaliplatin + Leucovorin + Fluorouracil
mFOLFOX-6 + Atezolizumab
BMS-813160 + Fluorouracil + Irinotecan + Leucovorin
Floxiuridine + Panitumumab + Dexamethasone + FOLFIRI
Panitumumab + FOLFIRI
Fluorouracil + Bevacizumab + Capecitabine + Irinotecan + Leucovorin
INCB024360 + Nivolumab + mFOLFOX6
Bevacizumab + FOLFOX
E7046 + mFOLFOX-6
Fluorouracil + Irinotecan + Leucovorin + Nivolumab
FOLFIRI + TRK-950 TRK-950 is a monoclonal antibody that targets a tumor associated antigen to induce immune mediated cytotoxicity of tumor cells (NCI Drug Dictionary).
Panitumumab + Fluorouracil + Leucovorin
mFOLFOX-6
Bevacizumab + FOLFIRINOX
R-MACLO/IVAM
Gemcitabine + Nab-Paclitaxel + mFOLFOX-6
Fluorouracil + Irinotecan + Leucovorin + MM-151
Panitumumab + FOLFOX
Fluorouracil + Leucovorin + Irinotecan + Oxaliplatin + Saridegib
Bevacizumab + FOLFIRI + PCM-075 PCM-075 inhibits PLK1, resulting in cell cycle arrest and apoptosis in cancer cells (J Clin Oncol 36, 2018 (suppl 6S; abstr 369)).
Dasatinib + FOLFOX
FOLFIRINOX
Trastuzumab + Fluorouracil + Leucovorin + Oxaliplatin
FOLFIRINOX + Losartan
Methotrexate + Cytarabine + Leucovorin
Ramucirumab + FOLFIRI
FOLFIRI
Necitumumab + FOLFOX
FOLFOX + Nivolumab + Relatlimab
NANT triple negative breast cancer vaccine combination
Cetuximab + FOLFIRI
FOLFIRI + OMP-305B83
Lapatinib + Irinotecan + Leucovorin + Fluorouracil
Regorafenib + FOLFOX
ABT-165 + FOLFIRI
Aflibercept + Leucovorin + Fluorouracil
Fluorouracil + Irinotecan + Leucovorin + Rucaparib