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Drug Name | Epacadostat |
Trade Name | |
Synonyms | INCB024360|INCB 024360|INCB-024360 |
Drug Descriptions |
Epacadostat (INCB024360) inhibits indoleamine 2,3-dioxygenase 1 (IDO1) to prevent tryptophan breakdown in the tumor microenvironment, thereby activating a cytotoxic immune response against IDO1 expressing tumor cells (PMID: 20197554, PMID: 32564277). |
DrugClasses | IDO1 Inhibitor 12 Immune Checkpoint Inhibitor 141 |
CAS Registry Number | 1204669-58-8 |
NCIT ID | C92582 |