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Drug Name Retifanlimab
Trade Name
Synonyms MGA 012|INCMGA00012|MGA012
Drug Descriptions

Retifanlimab (INCMGA00012) is a humanized IgG4 monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT085).

DrugClasses Immune Checkpoint Inhibitor 94 PD-L1/PD-1 antibody 63

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Epacadostat + Radiotherapy + Retifanlimab Bevacizumab Epacadostat Radiotherapy Retifanlimab 0 1
Bevacizumab + Radiotherapy + Retifanlimab Bevacizumab Radiotherapy Retifanlimab 0 1
Capecitabine + Margetuximab + Oxaliplatin + Retifanlimab Capecitabine Margetuximab Oxaliplatin Retifanlimab 0 1
Carboplatin + Nab-paclitaxel + Retifanlimab Carboplatin Nab-paclitaxel Retifanlimab 0 1
Carboplatin + Paclitaxel + Retifanlimab Carboplatin Paclitaxel Retifanlimab 0 2
Carboplatin + Pemetrexed Disodium + Retifanlimab Carboplatin Pemetrexed Disodium Retifanlimab 0 2
Cisplatin + Gemcitabine + Retifanlimab Cisplatin Gemcitabine Retifanlimab 0 1
Cisplatin + Pemetrexed Disodium + Retifanlimab Cisplatin Pemetrexed Disodium Retifanlimab 0 2
DPV-001 + INCAGN01876 + Retifanlimab DPV-001 INCAGN01876 Retifanlimab 0 1
DPV-001 + Retifanlimab DPV-001 Retifanlimab 0 1
Epacadostat + Retifanlimab Epacadostat Retifanlimab 0 1
Fluorouracil + Leucovorin + Margetuximab + Oxaliplatin + Retifanlimab Fluorouracil Leucovorin Margetuximab Oxaliplatin Retifanlimab 0 1
INCAGN01876 + Retifanlimab INCAGN01876 Retifanlimab 0 1
INCAGN02385 + INCAGN02390 + Retifanlimab INCAGN02385 INCAGN02390 Retifanlimab 0 1
Margetuximab + Retifanlimab Margetuximab Retifanlimab 0 1
MGC018 + Retifanlimab MGC018 Retifanlimab 0 1
MGD007 + Retifanlimab MGD007 Retifanlimab 0 1
MGD009 + Retifanlimab MGD009 Retifanlimab 0 1
Palbociclib + Retifanlimab Palbociclib Retifanlimab 0 1
Parsaclisib + Retifanlimab Parsaclisib Retifanlimab 0 1
Pelareorep + Retifanlimab Pelareorep Retifanlimab 0 1
Pemetrexed Disodium + Retifanlimab Pemetrexed Disodium Retifanlimab 0 1
Pemigatinib + Retifanlimab Pemigatinib Retifanlimab 0 1
Retifanlimab Retifanlimab 0 6


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