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| Drug Name | Retifanlimab |
| Trade Name | Zynyz |
| Synonyms | MGA 012|INCMGA00012|MGA012|retifanlimab-dlwr |
| Drug Descriptions |
Zynyz (retifanlimab) is a humanized IgG4 monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT085). Zynyz (retifanlimab) is FDA approved for use in adult patients with metastatic or recurrent locally advanced Merkel cell carcinoma (FDA.gov). |
| DrugClasses | Immune Checkpoint Inhibitor 146 PD-L1/PD-1 antibody 112 |
| CAS Registry Number | 2226345-85-1 |
| NCIT ID | C142168 |
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