Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Tretinoin
Trade Name Vesanoid
Synonyms Aberel|Aknoten|Avita|Renova|Retin-A|all-trans retinoic acid|Vitamin A Acid|ATRA
Drug Descriptions

Vesanoid (tretinoin) is a form of retinoic acid, which binds to retinoic acid receptors and activates downstream signaling, potentially inducing cell differentiation and subsequently, apoptosis (PMID: 11704842). Vesanoid (tretinoin) is FDA approved for patients with acute promyelocytic leukemia harboring PML-RARA (FDA.gov).

CAS Registry Number 302-79-4


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Anastrozole + Tretinoin Anastrozole Tretinoin 0 1
Arsenic trioxide + Cytarabine + Methotrexate + Tretinoin Arsenic trioxide Cytarabine Methotrexate Tretinoin 1 0
Arsenic trioxide + Gemtuzumab ozogamicin + Tretinoin Arsenic trioxide Gemtuzumab ozogamicin Tretinoin 0 3
Arsenic trioxide + Idarubicin + Tretinoin Arsenic trioxide Idarubicin Tretinoin 0 1
Arsenic trioxide + Tretinoin Arsenic trioxide Tretinoin 0 1
Atezolizumab + Tretinoin Atezolizumab Tretinoin 0 1
Azacitidine + Leuprolide + Tretinoin Azacitidine Leuprolide Tretinoin 0 1
Celecoxib + Itraconazole + Tretinoin Celecoxib Itraconazole Tretinoin 0 1
Cytarabine + Idarubicin + Tretinoin Cytarabine Idarubicin Tretinoin 0 1
Cytarabine + Tranylcypromine + Tretinoin Cytarabine Tranylcypromine Tretinoin 0 1
Daratumumab + Dexamethasone + Pomalidomide + Tretinoin Daratumumab Dexamethasone Pomalidomide Tretinoin 0 1
Dasatinib + Tretinoin Dasatinib Tretinoin 0 0
Decitabine + Tretinoin Decitabine Tretinoin 0 0
Idarubicin + Tretinoin Idarubicin Tretinoin 0 1
Mercaptopurine + Methotrexate + Tretinoin Mercaptopurine Methotrexate Tretinoin 0 1
Mitoxantrone + Tretinoin Mitoxantrone Tretinoin 0 1
Pembrolizumab + Tretinoin Pembrolizumab Tretinoin 0 1
Retifanlimab + Tretinoin Retifanlimab Tretinoin 0 1
RN-1 + Tretinoin RN-1 Tretinoin 0 0
TAS1440 + Tretinoin TAS1440 Tretinoin 0 1
Tranylcypromine + Tretinoin Tranylcypromine Tretinoin 0 1
Trastuzumab + Tretinoin Trastuzumab Tretinoin 0 0
Tretinoin Tretinoin 1 5

Additional content available in CKB BOOST