Drug Detail

Drug Name Methotrexate
Trade Name Abitrexate
Synonyms Amethopterin
Drug Descriptions

Methotrexate is an antimetabolite, which inhibits DHFR resulting in decreased immune function and antineoplastic activity (NCI Drug Dictionary). Methotrexate is FDA approved for psoriasis, RA, and several cancers including choriocarcinoma, AML, lung, head and neck and epidermoid (FDA.gov).

DrugClasses Chemotherapy - Antimetabolite 10

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Therapy Name Therapy Description
Cetuximab + Methotrexate
Methotrexate + Cisplatin + Cyclophosphamide + Vincristine
Sirolimus + Tacrolimus + Methotrexate
Tacrolimus + Methotrexate
Cytarabine + Dexamethasone + Methotrexate + Ponatinib + Rituximab + Venetoclax
Carboplatin + Methotrexate + Rituximab
Cytarabine + Methotrexate + Ponatinib
Sirolimus + Methotrexate
Cytarabine + Doxorubicin + Methotrexate + Vincristine
Cytarabine + Methotrexate + Venetoclax
Ara-C + Cyclophosphamide + Inotuzumab ozogamicin + Methotrexate + Vincristine
R-MACLO/IVAM
Vandetanib + Cyclophosphamide + Methotrexate
Ribociclib + Methotrexate
Cytarabine + Etoposide + Methotrexate
Cytarabine + Methotrexate
Cetuximab + Docetaxel + Methotrexate
Methotrexate + Cytarabine + Leucovorin
Cytarabine + Methotrexate + Rituximab
Cytarabine + Methotrexate + Prednisone
Cyclophosphamide + Methotrexate + Vincristine
Aldoxorubicin + Cisplatin + Filgrastim + Methotrexate + Vinblastine
Blinatumomab + Cytarabine + Dexamethasone + Methotrexate + Ponatinib
Cyclophosphamide + Methotrexate + Vincristine + Pegaspargase
Daunorubicin + Dexamethasone + Methotrexate + Pegaspargase + Vincristine
Aldoxorubicin + Cisplatin + Methotrexate + Vincristine
Cytarabine + Dexamethasone + Methotrexate + Vincristine
Arsenic trioxide + Cytarabine + Methotrexate + Tretinoin
Cytarabine + Methotrexate + Rituximab + Venetoclax
Vincristine + Methotrexate + Mercaptopurine
Cytarabine + Inotuzumab ozogamicin + Methotrexate
Methotrexate
Mercaptopurine + Methotrexate + Prednisone + Vincristine
Methotrexate + Regorafenib
Filgrastim + Methotrexate
Filgrastim + Methotrexate + Rituximab
Selinexor + Fludarabine phosphate + Cytarabine + Methotrexate + Prednisone
Cytarabine + Imatinib mesylate + Methotrexate
Methotrexate + Pegaspargase
Cytarabine + Dexamethasone+ Methotrexate
Methotrexate + UNC2025