Drug Detail

Drug Name Cetuximab
Trade Name Erbitux
Synonyms
Drug Descriptions

Erbitux (cetuximab) is a monoclonal antibody directed against EGFR, which inhibits signal transduction and cell proliferation (PMID: 28695301). Erbitux (cetuximab) is FDA approved for use in head and neck squamous cell carcinoma and KRAS wild-type, EGFR positive colorectal cancer (FDA.gov).

DrugClasses EGFR Antibody 27

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Cetuximab Afatinib Cetuximab 0 2
Afatinib + Cetuximab + Sirolimus Afatinib Cetuximab Sirolimus 0 0
Aldoxorubicin + ALT-803 + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Oxaliplatin + Regorafenib + Trastuzumab ALT-803 Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Oxaliplatin Regorafenib Trastuzumab haNK cells 0 1
Aldoxorubicin + ALT-803 + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Sorafenib ALT-803 Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Sorafenib haNK cells 0 1
Aldoxorubicin + ALT-803 + Avelumab + Cetuximab + ETBX-051 + ETBX-061 + GI-6301 + haNK cells ALT-803 Aldoxorubicin Avelumab Cetuximab ETBX-051 ETBX-061 GI-6301 haNK cells 0 1
Alpelisib + Cetuximab Alpelisib Cetuximab 0 2
Alpelisib + Cetuximab + Encorafenib Alpelisib Cetuximab Encorafenib 11 1
ALW-II-41-27 + Cetuximab ALW-II-41-27 Cetuximab 0 0
Avelumab + Cetuximab Avelumab Cetuximab 0 1
Avelumab + Cetuximab + Palbociclib Avelumab Cetuximab Palbociclib 0 1
AZD8055 + Cetuximab AZD8055 Cetuximab 0 0
Bevacizumab + Cetuximab Bevacizumab Cetuximab 1 1
Bevacizumab + Cetuximab + Fluorouracil + Irinotecan + Leucovorin Bevacizumab Cetuximab Fluorouracil Irinotecan Leucovorin 1 0
Bevacizumab + Cetuximab + Irinotecan Bevacizumab Cetuximab Irinotecan 0 1
Bevacizumab + Cetuximab + Temsirolimus Bevacizumab Cetuximab Temsirolimus 0 0
Bevacizumab + Cetuximab + Temsirolimus + Valproic acid Bevacizumab Cetuximab Temsirolimus Valproic acid 0 1
BGB-283 + Cetuximab BGB-283 Cetuximab 1 0
BGB-324 + Cetuximab BGB-324 Cetuximab 0 0
BGB659 + Cetuximab BGB659 Cetuximab 2 0
BI 882370 + Cetuximab BI 882370 Cetuximab 1 0
Binimetinib + Cetuximab + Encorafenib Binimetinib Cetuximab Encorafenib 3 2
Buparlisib + Cetuximab Buparlisib Cetuximab 0 0
C75 + Cetuximab C75 Cetuximab 0 0
Cabozantinib + Cetuximab Cabozantinib Cetuximab 0 1
Capmatinib + Cetuximab Capmatinib Cetuximab 0 1
Carboplatin + Cetuximab + Cisplatin + Fluorouracil Carboplatin Cetuximab Cisplatin Fluorouracil 0 3
Carboplatin + Cetuximab + Erlotinib + Paclitaxel Carboplatin Cetuximab Erlotinib Paclitaxel 0 1
Carboplatin + Cetuximab + Everolimus + Paclitaxel Carboplatin Cetuximab Everolimus Paclitaxel 0 1
Carboplatin + Cetuximab + Fluorouracil Carboplatin Cetuximab Fluorouracil 1 2
Carboplatin + Cetuximab + Nab-paclitaxel Carboplatin Cetuximab Nab-paclitaxel 0 2
Carboplatin + Cetuximab + Paclitaxel Carboplatin Cetuximab Paclitaxel 0 1
CC-95251 + Cetuximab CC-95251 Cetuximab 0 1
CDX-3379 + Cetuximab CDX-3379 Cetuximab 0 2
Cetuximab Cetuximab 72 39
Cetuximab + Cisplatin Cetuximab Cisplatin 0 3
Cetuximab + Cisplatin + Docetaxel Cetuximab Cisplatin Docetaxel 0 2
Cetuximab + Cisplatin + Docetaxel + Fluorouracil Cetuximab Cisplatin Docetaxel Fluorouracil 1 0
Cetuximab + Cisplatin + Epirubicin + Fluorouracil Cetuximab Cisplatin Epirubicin Fluorouracil 1 0
Cetuximab + Cisplatin + Fluorouracil + Radiotherapy Cetuximab Cisplatin Fluorouracil Radiotherapy 1 1
Cetuximab + Cisplatin + Irinotecan Cetuximab Cisplatin Irinotecan 1 0
Cetuximab + Cisplatin + Nab-paclitaxel Cetuximab Cisplatin Nab-paclitaxel 0 1
Cetuximab + Cisplatin + Paclitaxel Cetuximab Cisplatin Paclitaxel 0 1
Cetuximab + Cisplatin + Paclitaxel + Radiotherapy Cetuximab Cisplatin Paclitaxel Radiotherapy 1 0
Cetuximab + Cisplatin + Patritumab Cetuximab Cisplatin Patritumab 1 0
Cetuximab + Cisplatin + Vinorelbine Cetuximab Cisplatin Vinorelbine 1 0
Cetuximab + Cyclophosphamide Cetuximab Cyclophosphamide 0 1
Cetuximab + Dabrafenib Cetuximab Dabrafenib 6 0
Cetuximab + Dabrafenib + SCH772984 Cetuximab Dabrafenib SCH772984 2 0
Cetuximab + Dabrafenib + Trametinib Cetuximab Dabrafenib Trametinib 8 0
Cetuximab + Dasatinib Cetuximab Dasatinib 1 1
Cetuximab + Dasatinib + Fluorouracil + Leucovorin + Oxaliplatin Cetuximab Dasatinib Fluorouracil Leucovorin Oxaliplatin 1 0
Cetuximab + Docetaxel Cetuximab Docetaxel 0 3
Cetuximab + Docetaxel + Methotrexate Cetuximab Docetaxel Methotrexate 0 0
Cetuximab + Durvalumab Cetuximab Durvalumab 0 1
Cetuximab + EAI045 Cetuximab EAI045 0 0
Cetuximab + EGCG Cetuximab EGCG 0 0
Cetuximab + EGFR Antisense DNA Cetuximab EGFR Antisense DNA 1 0
Cetuximab + EGFR Antisense DNA + Radiotherapy Cetuximab EGFR Antisense DNA Radiotherapy 1 0
Cetuximab + Encorafenib Cetuximab Encorafenib 8 2
Cetuximab + Encorafenib + LGK974 Cetuximab Encorafenib LGK974 0 1
Cetuximab + FATE-NK100 Cetuximab FATE-NK100 0 1
Cetuximab + Ficlatuzumab Cetuximab Ficlatuzumab 0 2
Cetuximab + Floxuridine + Fluorouracil + Irinotecan Cetuximab Floxuridine Fluorouracil Irinotecan 0 0
Cetuximab + Fluorouracil Cetuximab Fluorouracil 0 1
Cetuximab + Fluorouracil + Irinotecan + Leucovorin Cetuximab Fluorouracil Irinotecan Leucovorin 7 5
Cetuximab + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Cetuximab Fluorouracil Irinotecan Leucovorin Oxaliplatin 2 1
Cetuximab + Fluorouracil + Leucovorin + Oxaliplatin Cetuximab Fluorouracil Leucovorin Oxaliplatin 4 3
Cetuximab + Fluorouracil + NC-6004 Cetuximab Fluorouracil NC-6004 0 1
Cetuximab + Hu5F9-G4 Cetuximab Hu5F9-G4 0 1
Cetuximab + Ibrutinib Cetuximab Ibrutinib 0 2
Cetuximab + IPH2201 Cetuximab IPH2201 1 1
Cetuximab + Ipilimumab Cetuximab Ipilimumab 0 1
Cetuximab + Irinotecan Cetuximab Irinotecan 4 5
Cetuximab + Irinotecan + Oxaliplatin Cetuximab Irinotecan Oxaliplatin 0 1
Cetuximab + Irinotecan + Ramucirumab Cetuximab Irinotecan Ramucirumab 0 1
Cetuximab + Irinotecan + Utomilumab Cetuximab Irinotecan Utomilumab 0 1
Cetuximab + Irinotecan + Vemurafenib Cetuximab Irinotecan Vemurafenib 3 2
Cetuximab + JNJ 38877605 Cetuximab JNJ 38877605 1 0
Cetuximab + Lapatinib Cetuximab Lapatinib 2 0
Cetuximab + Lenalidomide Cetuximab Lenalidomide 2 0
Cetuximab + Lenvatinib Cetuximab Lenvatinib 0 1
Cetuximab + LSN3074753 Cetuximab LSN3074753 4 0
Cetuximab + Luminespib Cetuximab Luminespib 0 1
Cetuximab + Lumretuzumab Cetuximab Lumretuzumab 1 0
Cetuximab + Mannitol Cetuximab Mannitol 0 1
Cetuximab + Methotrexate Cetuximab Methotrexate 0 0
Cetuximab + Motolimod Cetuximab Motolimod 1 0
Cetuximab + Nab-paclitaxel Cetuximab Nab-paclitaxel 0 1
Cetuximab + Napabucasin Cetuximab Napabucasin 0 1
Cetuximab + Neratinib Cetuximab Neratinib 0 2
Cetuximab + Nilotinib Cetuximab Nilotinib 0 1
Cetuximab + Nivolumab Cetuximab Nivolumab 0 3
Cetuximab + Olaparib Cetuximab Olaparib 0 1
Cetuximab + Osimertinib Cetuximab Osimertinib 0 0
Cetuximab + Paclitaxel Cetuximab Paclitaxel 0 1
Cetuximab + Palbociclib Cetuximab Palbociclib 0 3
Cetuximab + Pazopanib Cetuximab Pazopanib 1 1
Cetuximab + PEGPH20 Cetuximab PEGPH20 0 1
Cetuximab + Pembrolizumab Cetuximab Pembrolizumab 0 3
Cetuximab + Pertuzumab Cetuximab Pertuzumab 0 0
Cetuximab + PGG beta-glucan Cetuximab PGG beta-glucan 0 1
Cetuximab + PLX4720 Cetuximab PLX4720 1 0
Cetuximab + Prexasertib Cetuximab Prexasertib 1 1
Cetuximab + Prexasertib + Radiotherapy Cetuximab Prexasertib Radiotherapy 1 0
Cetuximab + REGN1400 Cetuximab REGN1400 0 1
Cetuximab + Regorafenib Cetuximab Regorafenib 3 2
Cetuximab + Savolitinib Cetuximab Savolitinib 0 1
Cetuximab + SCH772984 Cetuximab SCH772984 4 0
Cetuximab + Selumetinib Cetuximab Selumetinib 6 0
Cetuximab + Selumetinib + Vemurafenib Cetuximab Selumetinib Vemurafenib 0 0
Cetuximab + Sorafenib Cetuximab Sorafenib 1 0
Cetuximab + SP600125 Cetuximab SP600125 1 0
Cetuximab + Sunitinib Cetuximab Sunitinib 0 0
Cetuximab + Telisotuzumab vedotin Cetuximab Telisotuzumab vedotin 0 1
Cetuximab + Temsirolimus Cetuximab Temsirolimus 2 0
Cetuximab + TPST-1120 Cetuximab TPST-1120 0 1
Cetuximab + Trametinib Cetuximab Trametinib 6 0
Cetuximab + Trastuzumab Cetuximab Trastuzumab 0 0
Cetuximab + U0126 Cetuximab U0126 1 0
Cetuximab + Urelumab Cetuximab Urelumab 0 1
Cetuximab + Vemurafenib Cetuximab Vemurafenib 14 0