Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name FT538
Trade Name
Synonyms FT-538|FT 538
Drug Descriptions

FT538 consists of a preparation of natural killer cells derived from induced pluripotent stem cells engineered to lack CD38 and to express an IL-15 receptor alpha fusion protein and a non-cleavable form of CD16, which potentially induces enhanced antibody-dependent cellular cytotoxicity against tumor cells (Blood (2019) 134 (Supplement_1): 133).

CAS Registry Number NA
NCIT ID C176623


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + FT538 Atezolizumab FT538 0 1
Avelumab + FT538 Avelumab FT538 0 1
Cetuximab + FT538 Cetuximab FT538 0 1
Daratumumab + FT538 Daratumumab FT538 0 1
Daratumumab and hyaluronidase-fihj + FT538 Daratumumab and hyaluronidase-fihj FT538 0 1
Elotuzumab + FT538 Elotuzumab FT538 0 1
FT538 FT538 0 2
FT538 + MGA271 FT538 MGA271 0 1
FT538 + Nivolumab FT538 Nivolumab 0 1
FT538 + Pembrolizumab FT538 Pembrolizumab 0 1
FT538 + Trastuzumab FT538 Trastuzumab 0 1

Additional content available in CKB BOOST