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Drug Name FT538
Trade Name
Synonyms FT-538|FT 538
Drug Descriptions

FT538 consists of a preparation of natural killer cells derived from induced pluripotent stem cells engineered to lack CD38 and to express an IL-15 receptor alpha fusion protein and a non-cleavable form of CD16, which potentially induces enhanced antibody-dependent cellular cytotoxicity against tumor cells (Blood (2019) 134 (Supplement_1): 133).

DrugClasses
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + FT538 Atezolizumab FT538 0 1
Avelumab + FT538 Avelumab FT538 0 1
Cetuximab + FT538 Cetuximab FT538 0 1
Daratumumab + FT538 Daratumumab FT538 0 1
Daratumumab and hyaluronidase-fihj + FT538 Daratumumab and hyaluronidase-fihj FT538 0 1
Elotuzumab + FT538 Elotuzumab FT538 0 1
FT538 FT538 0 1
FT538 + Nivolumab FT538 Nivolumab 0 1
FT538 + Pembrolizumab FT538 Pembrolizumab 0 1
FT538 + Trastuzumab FT538 Trastuzumab 0 1


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