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Drug Name Elotuzumab
Trade Name Empliciti
Synonyms BMS-901608
Drug Descriptions

Empliciti (elotuzumab) is a humanized monoclonal antibody against human CS1, which induces antibody-dependent cellular cytotoxicity in CS1-positive cells (PMID: 26005365). Empliciti (elotuzumab) is approved in combination with Revlimid (lenalidomide) and dexamethasone for use in patients with multiple myeloma (FDA.gov).

DrugClasses
CAS Registry Number 915296-00-3
NCIT ID C66982

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Therapy Name Drugs Efficacy Evidence Clinical Trials
belantamab mafodotin-blmf + Elotuzumab Elotuzumab belantamab mafodotin-blmf 0 1
Bortezomib + Dexamethasone + Elotuzumab + Lenalidomide Bortezomib Dexamethasone Elotuzumab Lenalidomide 0 1
Bortezomib + Dexamethasone + Elotuzumab + Panobinostat Bortezomib Dexamethasone Elotuzumab Panobinostat 0 1
Carfilzomib + Dexamethasone + Elotuzumab + Lenalidomide Carfilzomib Dexamethasone Elotuzumab Lenalidomide 0 3
Carfilzomib + Dexamethasone + Elotuzumab + Pomalidomide Carfilzomib Dexamethasone Elotuzumab Pomalidomide 0 1
CC-92480 + Dexamethasone + Elotuzumab CC-92480 Dexamethasone Elotuzumab 0 1
Dexamethasone + Elotuzumab + Iberdomide Dexamethasone Elotuzumab Iberdomide 0 1
Dexamethasone + Elotuzumab + Isatuximab + Pomalidomide Dexamethasone Elotuzumab Isatuximab Pomalidomide 0 1
Dexamethasone + Elotuzumab + Lenalidomide Dexamethasone Elotuzumab Lenalidomide 0 5
Dexamethasone + Elotuzumab + Nivolumab + Pomalidomide Dexamethasone Elotuzumab Nivolumab Pomalidomide 0 1
Dexamethasone + Elotuzumab + Pomalidomide Dexamethasone Elotuzumab Pomalidomide 0 8
Elotuzumab Elotuzumab 0 8
Elotuzumab + FT538 Elotuzumab FT538 0 1
Elotuzumab + GDA-201 Elotuzumab GDA-201 0 0
Elotuzumab + Lenalidomide Elotuzumab Lenalidomide 0 4
Elotuzumab + Melphalan + Nogapendekin alfa inbakicept Elotuzumab Melphalan Nogapendekin alfa inbakicept 0 1
Elotuzumab + Nivolumab Elotuzumab Nivolumab 0 1


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