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Drug Name Bortezomib
Trade Name Velcade
Synonyms
Drug Descriptions

Velcade (bortezomib) is a reversible proteasome inhibitor that inhibits survival of malignant cells and regulates bone remodeling (PMID: 26579531). Velcade (bortezomib) is FDA approved for the treatment of mantle cell lymphoma and multiple myeloma (FDA.gov).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldoxorubicin + Bendamustine + Bortezomib Aldoxorubicin Bendamustine Bortezomib 0 0
Alisertib + Bortezomib + Rituximab Alisertib Bortezomib Rituximab 0 1
AO-176 + Bortezomib + Dexamethasone AO-176 Bortezomib Dexamethasone 0 1
BC2059 + Bortezomib BC2059 Bortezomib 1 0
Belantamab mafodotin + Bortezomib + Dexamethasone Belantamab mafodotin Bortezomib Dexamethasone 0 1
Belantamab mafodotin + Bortezomib + Dexamethasone + Lenalidomide Belantamab mafodotin Bortezomib Dexamethasone Lenalidomide 0 1
Bendamustine + Bortezomib + Ofatumumab Bendamustine Bortezomib Ofatumumab 0 1
Bendamustine + Bortezomib + Pegylated liposomal-doxorubicin Bendamustine Bortezomib Pegylated liposomal-doxorubicin 0 1
Bendamustine + Bortezomib + Rituximab Bendamustine Bortezomib Rituximab 1 0
Bevacizumab + Bortezomib Bevacizumab Bortezomib 0 1
Bevacizumab + Bortezomib + Temozolomide Bevacizumab Bortezomib Temozolomide 0 1
Bortezomib Bortezomib 6 39
Bortezomib + BX-912 BX-912 Bortezomib 0 0
Bortezomib + Cannabidiol Bortezomib Cannabidiol 0 1
Bortezomib + Carfilzomib + Clarithromycin Bortezomib Carfilzomib Clarithromycin 0 1
Bortezomib + CC-92480 + Dexamethasone Bortezomib CC-92480 Dexamethasone 0 1
Bortezomib + Cisplatin + Pembrolizumab Bortezomib Cisplatin Pembrolizumab 0 1
Bortezomib + Cladribine + Rituximab Bortezomib Cladribine Rituximab 0 1
Bortezomib + Clofarabine Bortezomib Clofarabine 0 1
Bortezomib + Cyclophosphamide Bortezomib Cyclophosphamide 0 2
Bortezomib + Cyclophosphamide + Daratumumab + Dexamethasone Bortezomib Cyclophosphamide Daratumumab Dexamethasone 0 1
Bortezomib + Cyclophosphamide + Dexamethasone + Fludarabine + JNJ-68284528 + Pomalidomide Bortezomib Cyclophosphamide Dexamethasone Fludarabine JNJ-68284528 Pomalidomide 0 1
Bortezomib + Cyclophosphamide + Filgrastim Bortezomib Cyclophosphamide Filgrastim 0 1
Bortezomib + Cyclophosphamide + Lenalidomide Bortezomib Cyclophosphamide Lenalidomide 0 1
Bortezomib + Cyclosporine + Mycophenolate mofetil Bortezomib Cyclosporine Mycophenolate mofetil 0 1
Bortezomib + Cytarabine + Etoposide + Midostaurin + Mitoxantrone Bortezomib Cytarabine Etoposide Midostaurin Mitoxantrone 1 0
Bortezomib + Daratumumab + Dexamethasone Bortezomib Daratumumab Dexamethasone 1 5
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide Bortezomib Daratumumab Dexamethasone Lenalidomide 0 5
Bortezomib + Daratumumab + Dexamethasone + Melphalan + Prednisone Bortezomib Daratumumab Dexamethasone Melphalan Prednisone 0 1
Bortezomib + Daratumumab + Dexamethasone + Thalidomide Bortezomib Daratumumab Dexamethasone Thalidomide 1 1
Bortezomib + Daratumumab + Dexamethasone + Venetoclax Bortezomib Daratumumab Dexamethasone Venetoclax 0 2
Bortezomib + Daratumumab + Melphalan Bortezomib Daratumumab Melphalan 0 0
Bortezomib + Daratumumab + Melphalan + Prednisone Bortezomib Daratumumab Melphalan Prednisone 1 0
Bortezomib + Daratumumab and hyaluronidase-fihj + Dexamethasone Bortezomib Daratumumab and hyaluronidase-fihj Dexamethasone 0 0
Bortezomib + Daratumumab and hyaluronidase-fihj + Melphalan + Prednisone Bortezomib Daratumumab and hyaluronidase-fihj Melphalan Prednisone 1 0
Bortezomib + Dasatinib + Dexamethasone + Doxorubicin + Palbociclib Bortezomib Dasatinib Dexamethasone Doxorubicin Palbociclib 0 1
Bortezomib + Decitabine + Sorafenib Bortezomib Decitabine Sorafenib 0 1
Bortezomib + Dexamethasone Bortezomib Dexamethasone 0 8
Bortezomib + Dexamethasone + Dinaciclib Bortezomib Dexamethasone Dinaciclib 0 1
Bortezomib + Dexamethasone + Elotuzumab + Lenalidomide Bortezomib Dexamethasone Elotuzumab Lenalidomide 0 1
Bortezomib + Dexamethasone + Elotuzumab + Panobinostat Bortezomib Dexamethasone Elotuzumab Panobinostat 0 1
Bortezomib + Dexamethasone + Iberdomide Bortezomib Dexamethasone Iberdomide 0 1
Bortezomib + Dexamethasone + Isatuximab + Lenalidomide Bortezomib Dexamethasone Isatuximab Lenalidomide 0 1
Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide 1 12
Bortezomib + Dexamethasone + Lenalidomide + Panobinostat Bortezomib Dexamethasone Lenalidomide Panobinostat 0 2
Bortezomib + Dexamethasone + Lenalidomide + TAK-079 Bortezomib Dexamethasone Lenalidomide TAK-079 0 1
Bortezomib + Dexamethasone + LGH447 Bortezomib Dexamethasone LGH447 0 0
Bortezomib + Dexamethasone + Linsitinib Bortezomib Dexamethasone Linsitinib 0 1
Bortezomib + Dexamethasone + Melflufen Bortezomib Dexamethasone Melflufen 0 1
Bortezomib + Dexamethasone + Melphalan + Thalidomide Bortezomib Dexamethasone Melphalan Thalidomide 0 2
Bortezomib + Dexamethasone + Panobinostat Bortezomib Dexamethasone Panobinostat 1 4
Bortezomib + Dexamethasone + Pelareorep Bortezomib Dexamethasone Pelareorep 0 1
Bortezomib + Dexamethasone + Pomalidomide Bortezomib Dexamethasone Pomalidomide 0 2
Bortezomib + Dexamethasone + Radium Ra 223 dichloride Bortezomib Dexamethasone Radium Ra 223 dichloride 0 1
Bortezomib + Dexamethasone + Ricolinostat Bortezomib Dexamethasone Ricolinostat 1 0
Bortezomib + Dexamethasone + Selinexor Bortezomib Dexamethasone Selinexor 0 1
Bortezomib + Dexamethasone + Ulocuplumab Bortezomib Dexamethasone Ulocuplumab 1 1
Bortezomib + Dexamethasone + Venetoclax Bortezomib Dexamethasone Venetoclax 1 2
Bortezomib + DT204 Bortezomib DT204 1 0
Bortezomib + Duvelisib Bortezomib Duvelisib 0 1
Bortezomib + Everolimus Bortezomib Everolimus 0 1
Bortezomib + Fasudil Bortezomib Fasudil 0 0
Bortezomib + Filgrastim Bortezomib Filgrastim 0 2
Bortezomib + Fludarabine + Melphalan Bortezomib Fludarabine Melphalan 0 1
Bortezomib + GO-203-2C Bortezomib GO-203-2C 0 1
Bortezomib + Ibrutinib Bortezomib Ibrutinib 0 1
Bortezomib + Lapatinib Bortezomib Lapatinib 0 1
Bortezomib + Lenalidomide Bortezomib Lenalidomide 0 1
Bortezomib + Lenalidomide + PAT-SM6 Bortezomib Lenalidomide PAT-SM6 0 0
Bortezomib + Metformin + Nelfinavir Bortezomib Metformin Nelfinavir 0 1
Bortezomib + Mivebresib Bortezomib Mivebresib 2 0
Bortezomib + Oxaliplatin Bortezomib Oxaliplatin 0 1
Bortezomib + Palbociclib Bortezomib Palbociclib 0 1
Bortezomib + Panobinostat Bortezomib Panobinostat 1 0
Bortezomib + Pegylated liposomal-doxorubicin Bortezomib Pegylated liposomal-doxorubicin 0 1
Bortezomib + Plerixafor Bortezomib Plerixafor 0 1
Bortezomib + Pravastatin Bortezomib Pravastatin 0 1
Bortezomib + Ribociclib Bortezomib Ribociclib 2 0
Bortezomib + Rituximab Bortezomib Rituximab 0 2
Bortezomib + Rituximab + Venetoclax Bortezomib Rituximab Venetoclax 0 1
Bortezomib + Ruxolitinib Bortezomib Ruxolitinib 0 1
Bortezomib + SJB3-019A Bortezomib SJB3-019A 1 0
Bortezomib + Sonidegib Bortezomib Sonidegib 0 1
Bortezomib + Sorafenib + Vorinostat Bortezomib Sorafenib Vorinostat 0 1
Bortezomib + Tapalumab Bortezomib Tapalumab 1 0
Bortezomib + Temozolomide Bortezomib Temozolomide 0 1
Bortezomib + Temsirolimus + Topotecan Bortezomib Temsirolimus Topotecan 1 0
Bortezomib + Tinostamustine Bortezomib Tinostamustine 7 0
Bortezomib + Torkinib Bortezomib Torkinib 1 0
Bortezomib + Vorinostat Bortezomib Vorinostat 1 0


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