Drug Detail

Drug Name Pegylated liposomal-doxorubicin
Trade Name Doxil
Synonyms ATI-0918|CAELYX
Drug Descriptions

Doxil (pegylated liposomal doxorubicin) is doxorubicin encapsulated within a liposome to allow better penetration into tumors, decrease toxicity, and increase the period of effectiveness. Doxorubicin intercalates into DNA, disrupting DNA replication (NCI Drug Dictionary). Doxil (pegylated liposomal doxorubicin) is FDA approved for ovarian cancer, AIDS-related Kaposi's sarcoma and multiple myeloma (FDA.gov).

DrugClasses Chemotherapy - Anthracycline 11

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Therapy Name Therapy Description
Doxil + RO6839921
Temozolomide + Etoposide + Doxil + Dexamethasone + Ibrutinib
Bevacizumab + Temsirolimus + Doxil
Doxil + romidepsin
Doxil + Pembrolizumab
Dexamethasone + pegylated liposomal-doxorubicin + Selinexor
Atezolizumab + Doxil
AB928 + Doxil AB928 is an antagonist of the adenosine receptors A2aR and A2bR, which may relieve adenosine-mediated immune suppression and lead to enhanced anti-tumor activity in combination with other agents (European Journal of Cancer, Vol 92, S14-S15).
Bendamustine + Bortezomib + pegylated liposomal-doxorubicin
Atezolizumab + Bevacizumab + Doxil
Doxil + Bevacizamub
Bortezomib + pegylated liposomal-doxorubicin
Pegylated liposomal-doxorubicin + Trebananib
Doxil Doxil (pegylated liposomal doxorubicin) is doxorubicin encapsulated within a liposome to allow better penetration into tumors, decrease toxicity, and increase the period of effectiveness. Doxorubicin intercalates into DNA, disrupting DNA replication (NCI Drug Dictionary). Doxil (pegylated liposomal doxorubicin) is FDA approved for ovarian cancer, AIDS-related Kaposi's sarcoma and multiple myeloma (FDA.gov).
Doxil + Paclitaxel
Motolimod + Pegylated liposomal-doxorubicin
Doxil + Pomalidomide
Doxil + Letrozole + Tamoxifen + Paclitaxel
pegylated liposomal doxorubicin + Veliparib
Carboplatin + Doxil + Everolimus
Doxil + Temsirolimus
LTX-315 + pegylated liposomal-doxorubicin