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Drug Name IPI-549
Trade Name
Synonyms
Drug Descriptions

IPI-549 is a selective PI3Kgamma inhibitor that enhances anti-tumor immune response and inhibits tumor growth in animal models (Cancer Immunol Res January 2016 4; B029).

DrugClasses PIK3CG inhibitor 8

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB928 + IPI-549 + Pegylated liposomal-doxorubicin AB928 IPI-549 Pegylated liposomal-doxorubicin 0 1
Atezolizumab + Bevacizumab + IPI-549 Atezolizumab Bevacizumab IPI-549 0 1
Atezolizumab + IPI-549 Atezolizumab IPI-549 0 0
Atezolizumab + IPI-549 + Nab-paclitaxel Atezolizumab IPI-549 Nab-paclitaxel 0 1
IPI-549 IPI-549 1 2
IPI-549 + Nivolumab IPI-549 Nivolumab 0 1


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