Drug Detail


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Drug Name Eganelisib
Trade Name
Synonyms IPI 549|IPI549|IPI-549
Drug Descriptions

Eganelisib is a selective PI3Kgamma inhibitor, which potentially results in enhanced anti-tumor immune response via T-cell activation and inhibition of tumor growth (PMID: 27828943, PMID: 37000164).

DrugClasses PIK3CG inhibitor 10
CAS Registry Number 1693758-51-8
NCIT ID C125471


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Eganelisib Atezolizumab Bevacizumab Eganelisib 0 1
Atezolizumab + Eganelisib Atezolizumab Eganelisib 0 0
Atezolizumab + Eganelisib + Nab-paclitaxel Atezolizumab Eganelisib Nab-paclitaxel 0 1
Eganelisib Eganelisib 0 2
Eganelisib + Etrumadenant + Pegylated liposomal doxorubicin Eganelisib Etrumadenant Pegylated liposomal doxorubicin 0 1
Eganelisib + Nivolumab Eganelisib Nivolumab 0 1

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