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Drug Name | Bevacizumab |
Trade Name | Avastin |
Synonyms | |
Drug Descriptions |
Avastin (bevacizumab) is a monoclonal antibody that binds VEGF and inhibits binding to VEGFR, potentially resulting in decreased tumor growth (PMID: 15136787). Avastin (bevacizumab) is FDA approved for use in colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, cervical carcinoma, and ovarian cancer, and in combination with carboplatin and paclitaxel in epithelial ovarian, fallopian tube, or primary peritoneal cancer (FDA.gov). |
DrugClasses | VEGF Antibody 11 VEGFR Inhibitor (Pan) 36 |
CAS Registry Number | 216974-75-3 |
NCIT ID | C2039 |