Drug Detail


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Drug Name Altiratinib
Trade Name
Synonyms DCC-2701
Drug Descriptions

Altiratinib (DCC-2701) is an inhibitor of MET, VEGFR2, TIE2, and Trk that decreases endothelial cell survival and may inhibit cell proliferation and increase cell death in tumors expressing these factors (PMID: 26965451).

DrugClasses MET Inhibitor 59 Trk Receptor Inhibitor (Pan) 31
CAS Registry Number 1345847-93-9
NCIT ID C118290


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Altiratinib Altiratinib 1 1
Altiratinib + Bevacizumab Altiratinib Bevacizumab 0 0
Altiratinib + Dabrafenib Altiratinib Dabrafenib 0 0
Altiratinib + Trametinib Altiratinib Trametinib 0 0

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