Drug Detail


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Drug Name GLS-010
Trade Name
Synonyms AB122|AB-122|Zimberelimab|GLS010
Drug Descriptions

Zimberelimab (GLS-010) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 28679395).

DrugClasses Immune Checkpoint Inhibitor 135 PD-L1/PD-1 antibody 79
CAS Registry Number NA
NCIT ID C159549


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB154 + AB928 + GLS-010 AB154 AB928 GLS-010 0 2
AB154 + GLS-010 AB154 GLS-010 0 4
AB308 + GLS-010 AB308 GLS-010 0 1
AB680 + AB928 + GLS-010 AB680 AB928 GLS-010 0 2
AB680 + GLS-010 AB680 GLS-010 0 1
AB928 + Bevacizumab + Fluorouracil + GLS-010 + Leucovorin + Oxaliplatin AB928 Bevacizumab Fluorouracil GLS-010 Leucovorin Oxaliplatin 0 1
AB928 + Docetaxel + GLS-010 AB928 Docetaxel GLS-010 0 1
AB928 + Enzalutamide + GLS-010 AB928 Enzalutamide GLS-010 0 1
AB928 + Fluorouracil + GLS-010 + Leucovorin + Oxaliplatin AB928 Fluorouracil GLS-010 Leucovorin Oxaliplatin 0 2
AB928 + GLS-010 AB928 GLS-010 0 2
GLS-010 GLS-010 0 4

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