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Drug Name AB680
Trade Name
Synonyms AB-680|AB 680
Drug Descriptions

AB680 is an inhibitor that selectively targets CD73, resulting in decreased production of extracellular adenosine (ADO), and potentially leading to decreased ADO-mediated T-cell suppression and improved anti-tumor immunity (Cancer Res 2018;78(13 Suppl):Abstract nr 1756, PMID: 32614585).

DrugClasses Adenosine Targeting 16

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB680 AB680 0 0
AB680 + AB928 AB680 AB928 0 1
AB680 + AB928 + GLS-010 AB680 AB928 GLS-010 0 1
AB680 + GLS-010 AB680 GLS-010 0 1


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