Drug Detail

Drug Name Oxaliplatin
Trade Name Eloxatin
Synonyms Diaminocyclohexane Oxalatoplatinum
Drug Descriptions

Eloxatin (oxaliplatin) is comprised of a platinum complex, which causes DNA-platinum cross-links, inhibition of DNA replication and transcription, and cell toxicity (NCI Drug Dictionary). Eloxatin (oxaliplatin) is FDA approved for colorectal cancer (FDA.gov).

DrugClasses Chemotherapy - Platinum 6

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB928 + Fluorouracil + Leucovorin + Oxaliplatin AB928 Fluorouracil Leucovorin Oxaliplatin 0 1
AB928 + Oxaliplatin AB928 Oxaliplatin 1 0
ABT-737 + Oxaliplatin ABT-737 Oxaliplatin 1 0
Ad-CEA vaccine + Avelumab + Bevacizumab + Capecitabine + Fluorouracil + Leucovorin + Oxaliplatin Ad-CEA vaccine Avelumab Bevacizumab Capecitabine Fluorouracil Leucovorin Oxaliplatin 0 1
Aflibercept + Fluorouracil + Leucovorin + Oxaliplatin Aflibercept Fluorouracil Leucovorin Oxaliplatin 0 1
Aldoxorubicin + ALT-803 + Avelumab + Bevacizumab + Capecitabine + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + Gemcitabine + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Oxaliplatin ALT-803 Aldoxorubicin Avelumab Bevacizumab Capecitabine Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Gemcitabine Leucovorin Nab-paclitaxel Oxaliplatin haNK cells 0 2
Aldoxorubicin + ALT-803 + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Oxaliplatin + Regorafenib + Trastuzumab ALT-803 Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Oxaliplatin Regorafenib Trastuzumab haNK cells 0 1
Atezolizumab + Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin Atezolizumab Bevacizumab Fluorouracil Leucovorin Oxaliplatin 0 2
Atezolizumab + Cobimetinib + Fluorouracil + Leucovorin + Oxaliplatin Atezolizumab Cobimetinib Fluorouracil Leucovorin Oxaliplatin 0 1
Atezolizumab + Fluorouracil + Leucovorin + Oxaliplatin Atezolizumab Fluorouracil Leucovorin Oxaliplatin 0 2
Atezolizumab + Fluorouracil + Oxaliplatin Atezolizumab Fluorouracil Oxaliplatin 0 1
Atezolizumab + Gemcitabine + Oxaliplatin + Rituximab Atezolizumab Gemcitabine Oxaliplatin Rituximab 0 1
Avelumab + Fluorouracil + Leucovorin + Oxaliplatin + Trastuzumab Avelumab Fluorouracil Leucovorin Oxaliplatin Trastuzumab 0 1
Axitinib + Fluorouracil + Leucovorin + Oxaliplatin Axitinib Fluorouracil Leucovorin Oxaliplatin 1 0
Bevacizumab + Cannabidiol + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Bevacizumab Cannabidiol Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
Bevacizumab + Capecitabine + Fluorouracil + Leucovorin + Oxaliplatin Bevacizumab Capecitabine Fluorouracil Leucovorin Oxaliplatin 0 1
Bevacizumab + Capecitabine + Oxaliplatin Bevacizumab Capecitabine Oxaliplatin 0 3
Bevacizumab + Capecitabine + Oxaliplatin + Trastuzumab Bevacizumab Capecitabine Oxaliplatin Trastuzumab 1 0
Bevacizumab + Durvalumab + Fluorouracil + Leucovorin + Oxaliplatin + Tremelimumab Bevacizumab Durvalumab Fluorouracil Leucovorin Oxaliplatin Tremelimumab 0 1
Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Bevacizumab Fluorouracil Irinotecan Leucovorin Oxaliplatin 1 2
Bevacizumab + Fluorouracil + Irinotecan + Oxaliplatin Bevacizumab Fluorouracil Irinotecan Oxaliplatin 1 0
Bevacizumab + Fluorouracil + Leucovorin + Nab-paclitaxel + Oxaliplatin Bevacizumab Fluorouracil Leucovorin Nab-paclitaxel Oxaliplatin 0 1
Bevacizumab + Fluorouracil + Leucovorin + Nab-Rapamycin + Oxaliplatin Bevacizumab Fluorouracil Leucovorin Nab-Rapamycin Oxaliplatin 0 1
Bevacizumab + Fluorouracil + Leucovorin + NANT-008 + Oxaliplatin Bevacizumab Fluorouracil Leucovorin NANT-008 Oxaliplatin 0 1
Bevacizumab + Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin Bevacizumab Fluorouracil Leucovorin Nivolumab Oxaliplatin 0 1
Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin Bevacizumab Fluorouracil Leucovorin Oxaliplatin 1 11
Bevacizumab + Fluorouracil + Oxaliplatin Bevacizumab Fluorouracil Oxaliplatin 0 1
Bevacizumab + Gemcitabine + Oxaliplatin Bevacizumab Gemcitabine Oxaliplatin 0 2
Bevacizumab + Oxaliplatin + Sorafenib Bevacizumab Oxaliplatin Sorafenib 0 1
BGB-A317 + Capecitabine + Oxaliplatin BGB-A317 Capecitabine Oxaliplatin 0 1
BGJ398 + Fluorouracil + Irinotecan + Oxaliplatin BGJ398 Fluorouracil Irinotecan Oxaliplatin 0 1
BGJ398 + Oxaliplatin BGJ398 Oxaliplatin 0 0
Binimetinib + Fluorouracil + Leucovorin + Oxaliplatin Binimetinib Fluorouracil Leucovorin Oxaliplatin 1 1
Binimetinib + Fluorouracil + Leucovorin + Oxaliplatin + Pembrolizumab Binimetinib Fluorouracil Leucovorin Oxaliplatin Pembrolizumab 0 1
Binimetinib + Gemcitabine + Oxaliplatin Binimetinib Gemcitabine Oxaliplatin 0 1
Bortezomib + Oxaliplatin Bortezomib Oxaliplatin 0 1
BSI-401 + Oxaliplatin BSI-401 Oxaliplatin 0 0
Capecitabine + Claudiximab + Oxaliplatin Capecitabine Claudiximab Oxaliplatin 0 1
Capecitabine + Epirubicin + Oxaliplatin + Pembrolizumab Capecitabine Epirubicin Oxaliplatin Pembrolizumab 0 1
Capecitabine + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Capecitabine Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
Capecitabine + Fluorouracil + Oxaliplatin + Talimogene laherparepvec Capecitabine Fluorouracil Oxaliplatin Talimogene laherparepvec 0 1
Capecitabine + Lapatinib + Oxaliplatin Capecitabine Lapatinib Oxaliplatin 2 1
Capecitabine + Nivolumab + Oxaliplatin Capecitabine Nivolumab Oxaliplatin 0 1
Capecitabine + Nivolumab + Oxaliplatin + Relatlimab Capecitabine Nivolumab Oxaliplatin Relatlimab 0 1
Capecitabine + Oxaliplatin Capecitabine Oxaliplatin 0 8
Capecitabine + Oxaliplatin + Pembrolizumab Capecitabine Oxaliplatin Pembrolizumab 0 2
Capecitabine + Oxaliplatin + Pembrolizumab + Trastuzumab Capecitabine Oxaliplatin Pembrolizumab Trastuzumab 0 1
Capecitabine + Oxaliplatin + Trastuzumab Capecitabine Oxaliplatin Trastuzumab 0 1
Capecitabine + Oxaliplatin + Vandetanib Capecitabine Oxaliplatin Vandetanib 1 0
Cetuximab + Dasatinib + Fluorouracil + Leucovorin + Oxaliplatin Cetuximab Dasatinib Fluorouracil Leucovorin Oxaliplatin 1 0
Cetuximab + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Cetuximab Fluorouracil Irinotecan Leucovorin Oxaliplatin 2 1
Cetuximab + Fluorouracil + Leucovorin + Oxaliplatin Cetuximab Fluorouracil Leucovorin Oxaliplatin 4 3
Cetuximab + Irinotecan + Oxaliplatin Cetuximab Irinotecan Oxaliplatin 0 1
Ch282-5 + Oxaliplatin Ch282-5 Oxaliplatin 1 0
Cisplatin + Doxorubicin + Gemcitabine + Oxaliplatin + Sorafenib Cisplatin Doxorubicin Gemcitabine Oxaliplatin Sorafenib 0 1
Claudiximab + Fluorouracil + Leucovorin + Oxaliplatin Claudiximab Fluorouracil Leucovorin Oxaliplatin 0 2
CPI-613 + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin CPI-613 Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 1
CV301 + Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin CV301 Fluorouracil Leucovorin Nivolumab Oxaliplatin 0 1
Cytarabine + Dexamethasone + Oxaliplatin Cytarabine Dexamethasone Oxaliplatin 0 1
Dasatinib + Fluorouracil + Leucovorin + Oxaliplatin Dasatinib Fluorouracil Leucovorin Oxaliplatin 1 0
Dbait + Fluorouracil + Oxaliplatin Dbait Fluorouracil Oxaliplatin 1 0
Dexamethasone + Gemcitabine + Oxaliplatin Dexamethasone Gemcitabine Oxaliplatin 0 1
DT01 + Fluorouracil + Oxaliplatin DT01 Fluorouracil Oxaliplatin 1 0
Durvalumab + Fluorouracil + Leucovorin + Oleclumab + Oxaliplatin Durvalumab Fluorouracil Leucovorin Oleclumab Oxaliplatin 0 1
Durvalumab + Fluorouracil + Leucovorin + Oxaliplatin + Tremelimumab Durvalumab Fluorouracil Leucovorin Oxaliplatin Tremelimumab 0 1
E7046 + Fluorouracil + Leucovorin + Oxaliplatin E7046 Fluorouracil Leucovorin Oxaliplatin 0 1
Epacadostat + Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin Epacadostat Fluorouracil Leucovorin Nivolumab Oxaliplatin 0 1
Floxuridine + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab Floxuridine Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 0 1
Fluorouracil + FPA144 + Leucovorin + Oxaliplatin FPA144 Fluorouracil Leucovorin Oxaliplatin 0 1
Fluorouracil + Gemcitabine + Leucovorin + Nab-paclitaxel + Oxaliplatin + Pembrolizumab Fluorouracil Gemcitabine Leucovorin Nab-paclitaxel Oxaliplatin Pembrolizumab 0 1
Fluorouracil + INCB001158 + Leucovorin + Oxaliplatin Fluorouracil INCB001158 Leucovorin Oxaliplatin 0 1
Fluorouracil + Irinotecan + Leucovorin + Losartan + Nivolumab + Oxaliplatin Fluorouracil Irinotecan Leucovorin Losartan Nivolumab Oxaliplatin 0 1
Fluorouracil + Irinotecan + Leucovorin + Losartan + Oxaliplatin Fluorouracil Irinotecan Leucovorin Losartan Oxaliplatin 0 1
Fluorouracil + Irinotecan + Leucovorin + Nivolumab + Oxaliplatin Fluorouracil Irinotecan Leucovorin Nivolumab Oxaliplatin 0 2
Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 7
Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Panitumumab Fluorouracil Irinotecan Leucovorin Oxaliplatin Panitumumab 2 0
Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + Saridegib Fluorouracil Irinotecan Leucovorin Oxaliplatin Saridegib 0 1
Fluorouracil + Irinotecan + Oxaliplatin + Panitumumab Fluorouracil Irinotecan Oxaliplatin Panitumumab 5 0
Fluorouracil + Lapatinib + Leucovorin + Oxaliplatin Fluorouracil Lapatinib Leucovorin Oxaliplatin 0 1
Fluorouracil + Leucovorin + Necitumumab + Oxaliplatin Fluorouracil Leucovorin Necitumumab Oxaliplatin 2 0
Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin Fluorouracil Leucovorin Nivolumab Oxaliplatin 0 2
Fluorouracil + Leucovorin + Nivolumab + Oxaliplatin + Relatlimab Fluorouracil Leucovorin Nivolumab Oxaliplatin Relatlimab 0 1
Fluorouracil + Leucovorin + Oleclumab + Oxaliplatin Fluorouracil Leucovorin Oleclumab Oxaliplatin 0 1
Fluorouracil + Leucovorin + Onartuzumab + Oxaliplatin Fluorouracil Leucovorin Onartuzumab Oxaliplatin 2 0
Fluorouracil + Leucovorin + Oxaliplatin Fluorouracil Leucovorin Oxaliplatin 0 8
Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Fluorouracil Leucovorin Oxaliplatin Panitumumab 2 2
Fluorouracil + Leucovorin + Oxaliplatin + Pegilodecakin Fluorouracil Leucovorin Oxaliplatin Pegilodecakin 0 1
Fluorouracil + Leucovorin + Oxaliplatin + Pembrolizumab Fluorouracil Leucovorin Oxaliplatin Pembrolizumab 0 38
Fluorouracil + Leucovorin + Oxaliplatin + Ramucirumab Fluorouracil Leucovorin Oxaliplatin Ramucirumab 1 0
Fluorouracil + Leucovorin + Oxaliplatin + Regorafenib Fluorouracil Leucovorin Oxaliplatin Regorafenib 0 1
Fluorouracil + Leucovorin + Oxaliplatin + Tivozanib Fluorouracil Leucovorin Oxaliplatin Tivozanib 1 0
Fluorouracil + Leucovorin + Oxaliplatin + Trastuzumab Fluorouracil Leucovorin Oxaliplatin Trastuzumab 2 0
Fluorouracil + Leucovorin + Oxaliplatin + Vandetanib Fluorouracil Leucovorin Oxaliplatin Vandetanib 1 0
Fluorouracil + Leucovorin + Oxaliplatin + ZW25 Fluorouracil Leucovorin Oxaliplatin ZW25 0 1
Fluorouracil + Oxaliplatin Fluorouracil Oxaliplatin 0 1
Fluorouracil + Oxaliplatin + Palbociclib Fluorouracil Oxaliplatin Palbociclib 0 1
Fluorouracil + Oxaliplatin + Panitumumab Fluorouracil Oxaliplatin Panitumumab 0 0
Fluorouracil + Oxaliplatin + Trastuzumab Fluorouracil Oxaliplatin Trastuzumab 1 0
Gemcitabine + MT-3724 + Oxaliplatin Gemcitabine MT-3724 Oxaliplatin 0 1
Gemcitabine + Nivolumab + Oxaliplatin Gemcitabine Nivolumab Oxaliplatin 0 1
Gemcitabine + Oxaliplatin Gemcitabine Oxaliplatin 0 1
Gemcitabine + Oxaliplatin + Panitumumab Gemcitabine Oxaliplatin Panitumumab 1 0
Gemcitabine + Oxaliplatin + Rituximab Gemcitabine Oxaliplatin Rituximab 0 2
Gemcitabine + Oxaliplatin + Sorafenib Gemcitabine Oxaliplatin Sorafenib 0 0
KX2-391 + Oxaliplatin KX2-391 Oxaliplatin 2 0
MN58b + Oxaliplatin MN58b Oxaliplatin 1 0
ON01910 + Oxaliplatin ON01910 Oxaliplatin 1 0
Oxaliplatin Oxaliplatin 4 13
Oxaliplatin + Pembrolizumab + Trastuzumab + TS-1 Oxaliplatin Pembrolizumab TS-1 Trastuzumab 0 1
Oxaliplatin + Ramucirumab + TS-1 Oxaliplatin Ramucirumab TS-1 2 0
Oxaliplatin + Resminostat Oxaliplatin Resminostat 1 0
Oxaliplatin + Trastuzumab Oxaliplatin Trastuzumab 2 0
Oxaliplatin + Trastuzumab + TS-1 Oxaliplatin TS-1 Trastuzumab 1 1