Drug Detail

Drug Name Ramucirumab
Trade Name Cyramza
Synonyms LY3009806
Drug Descriptions

Cyramza (ramucirumab) is a monoclonal antibody, which binds and inhibits VEGFR2 (KDR) resulting in decreased angiogenesis (PMID: 24094768). Cyramza (ramucirumab) is approved for gastric and gastroesophageal junction adenocarcinoma, non-small cell lung cancer, hepatocellular carcinoma, and colorectal cancer (FDA.gov).

DrugClasses VEGFR2 Antibody 4

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Ramucirumab Abemaciclib Ramucirumab 1 1
Atezolizumab + Ramucirumab Atezolizumab Ramucirumab 0 1
Carboplatin + Paclitaxel + Ramucirumab Carboplatin Paclitaxel Ramucirumab 1 1
Cetuximab + Irinotecan + Ramucirumab Cetuximab Irinotecan Ramucirumab 0 1
Crenolanib + Paclitaxel + Ramucirumab Crenolanib Paclitaxel Ramucirumab 0 1
Dacarbazine + Ramucirumab Dacarbazine Ramucirumab 0 0
Docetaxel + Ramucirumab Docetaxel Ramucirumab 4 1
Durvalumab + Ramucirumab Durvalumab Ramucirumab 0 1
Emibetuzumab + Ramucirumab Emibetuzumab Ramucirumab 0 1
Erlotinib + Ramucirumab Erlotinib Ramucirumab 0 1
Fluorouracil + Irinotecan + Leucovorin + Ramucirumab Fluorouracil Irinotecan Leucovorin Ramucirumab 2 0
Fluorouracil + Leucovorin + Oxaliplatin + Ramucirumab Fluorouracil Leucovorin Oxaliplatin Ramucirumab 1 0
Gefitinib + Ramucirumab Gefitinib Ramucirumab 0 1
Irinotecan + Ramucirumab Irinotecan Ramucirumab 0 1
LY3300054 + Ramucirumab LY3300054 Ramucirumab 0 1
Merestinib + Ramucirumab Merestinib Ramucirumab 0 1
MM-398 + Ramucirumab MM-398 Ramucirumab 0 1
Nab-paclitaxel + Ramucirumab Nab-paclitaxel Ramucirumab 0 2
Nivolumab + Ramucirumab Nivolumab Ramucirumab 1 2
Octreotide + Ramucirumab Octreotide Ramucirumab 0 1
Olaparib + Ramucirumab Olaparib Ramucirumab 0 1
Oraxol + Ramucirumab Oraxol Ramucirumab 0 1
Osimertinib + Ramucirumab Osimertinib Ramucirumab 0 2
Oxaliplatin + Ramucirumab + TS-1 Oxaliplatin Ramucirumab TS-1 2 0
Paclitaxel + Ramucirumab Paclitaxel Ramucirumab 2 2
Paclitaxel + Ramucirumab + TRK-950 Paclitaxel Ramucirumab TRK-950 0 1
Pembrolizumab + Ramucirumab Pembrolizumab Ramucirumab 0 3
Ramucirumab Ramucirumab 10 12
Ramucirumab + Trastuzumab Ramucirumab Trastuzumab 0 1
Ramucirumab + trifluridine/tipiracil hydrochloride Ramucirumab trifluridine/tipiracil hydrochloride 0 1