Drug Detail


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Drug Name ZW25
Trade Name
Synonyms ZW-25|Zanidatamab
Drug Descriptions

Zanidatamab (ZW25) is a bispecific antibody targeting ERBB2 (HER2), which induces anti-tumor immune response against Erbb2 (Her2)-expressing tumors (Ann Oncol 2017, Vol 28, Suppl 5, Abstract # 255P, PMID: 32054397).

DrugClasses HER2 (ERBB2) Antibody 53
CAS Registry Number 2169946-15-8
NCIT ID C130010


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ALX148 + ZW25 ALX148 ZW25 0 1
Capecitabine + Cisplatin + ZW25 Capecitabine Cisplatin ZW25 0 0
Capecitabine + Oxaliplatin + ZW25 Capecitabine Oxaliplatin ZW25 0 1
Capecitabine + ZW25 Capecitabine ZW25 0 1
Cisplatin + Fluorouracil + Leucovorin + ZW25 Cisplatin Fluorouracil Leucovorin ZW25 0 0
Cisplatin + Fluorouracil + ZW25 Cisplatin Fluorouracil ZW25 0 1
Fluorouracil + Leucovorin + Oxaliplatin + ZW25 Fluorouracil Leucovorin Oxaliplatin ZW25 0 1
Fulvestrant + Palbociclib + ZW25 Fulvestrant Palbociclib ZW25 0 1
Letrozole + Tamoxifen + ZW25 Letrozole Tamoxifen ZW25 0 0
Letrozole + ZW25 Letrozole ZW25 0 1
Paclitaxel + ZW25 Paclitaxel ZW25 0 1
Tamoxifen + ZW25 Tamoxifen ZW25 0 1
Vinorelbine + ZW25 Vinorelbine ZW25 0 1
ZW25 ZW25 0 4

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