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Drug Name JQ1
Trade Name
Synonyms
Drug Descriptions

JQ1 is a BET bromodomain inhibitor with greatest specificity towards BRD4, resulting in decreased Myc expression, increased cell death, reduced macrophage immunosuppression, and inhibition of tumor growth (PMID: 24231268, PMID: 31018997, PMID: 30906568).

DrugClasses BET Inhibitor (Pan) 27

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Arsenic trioxide + Chloroquine + JQ1 Arsenic trioxide Chloroquine JQ1 1 0
Arsenic trioxide + JQ1 Arsenic trioxide JQ1 1 0
BAZ2-ICR + BI-9564 + JQ1 BAZ2-ICR BI-9564 JQ1 1 0
BAZ2-ICR + JQ1 BAZ2-ICR JQ1 1 0
Carboplatin + JQ1 Carboplatin JQ1 1 0
Cisplatin + JQ1 Cisplatin JQ1 1 0
Dasatinib + JQ1 Dasatinib JQ1 0 0
Docetaxel + JQ1 Docetaxel JQ1 1 0
Gemcitabine + JQ1 Gemcitabine JQ1 1 0
GSK2801 + JQ1 GSK2801 JQ1 1 0
HY-16462 + JQ1 HY-16462 JQ1 1 0
I-CBP112 + JQ1 I-CBP112 JQ1 2 0
Ixazomib + JQ1 Ixazomib JQ1 2 0
JQ1 JQ1 15 0
JQ1 + MRK-003 JQ1 MRK-003 1 0
JQ1 + Osimertinib JQ1 Osimertinib 1 0
JQ1 + Paclitaxel JQ1 Paclitaxel 1 0
JQ1 + Panobinostat JQ1 Panobinostat 0 0
JQ1 + PF-3758309 JQ1 PF-3758309 0 0
JQ1 + Ribociclib JQ1 Ribociclib 2 0
JQ1 + SCH772984 JQ1 SCH772984 0 0
JQ1 + Silmitasertib JQ1 Silmitasertib 1 0
JQ1 + Trametinib JQ1 Trametinib 0 0
JQ1 + VE-821 JQ1 VE-821 0 0
JQ1 + Vemurafenib JQ1 Vemurafenib 0 0
JQ1 + Vinorelbine JQ1 Vinorelbine 1 0


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