Drug Detail

Drug Name Ixazomib
Trade Name Ninlaro
Synonyms MLN9708
Drug Descriptions

Ninlaro (ixazomib) inhibits proteosome activity, resulting in accumulation of misfolded proteins, inhibition of pathway signaling, and potentially leading to cell death (PMID: 20160034).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Dexamethasone + Ixazomib + Pomalidomide Abemaciclib Dexamethasone Ixazomib Pomalidomide 0 1
AZD7762 + Ixazomib AZD7762 Ixazomib 1 0
Cobimetinib + Dexamethasone + Ixazomib + Pomalidomide Cobimetinib Dexamethasone Ixazomib Pomalidomide 0 1
Daratumumab + Dexamethasone + Ixazomib Daratumumab Dexamethasone Ixazomib 0 2
Daratumumab + Dexamethasone + Ixazomib + Pomalidomide Daratumumab Dexamethasone Ixazomib Pomalidomide 0 1
Dexamethasone + Enasidenib + Ixazomib + Pomalidomide Dexamethasone Enasidenib Ixazomib Pomalidomide 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Dexamethasone + Idasanutlin + Ixazomib Dexamethasone Idasanutlin Ixazomib 0 1
Dexamethasone + Ixazomib Dexamethasone Ixazomib 0 1
Dexamethasone + Ixazomib + Lenalidomide Dexamethasone Ixazomib Lenalidomide 0 2
Dexamethasone + Ixazomib + ONC201 Dexamethasone Ixazomib ONC201 0 1
Dexamethasone + Ixazomib + Panobinostat Dexamethasone Ixazomib Panobinostat 0 1
Dexamethasone + Ixazomib + Pomalidomide + Venetoclax Dexamethasone Ixazomib Pomalidomide Venetoclax 0 1
Dexamethasone + Ixazomib + Selinexor Dexamethasone Ixazomib Selinexor 0 1
DT204 + Ixazomib DT204 Ixazomib 1 0
Erlotinib + Ixazomib Erlotinib Ixazomib 0 1
Fulvestrant + Ixazomib Fulvestrant Ixazomib 0 1
Ibrutinib + Ixazomib Ibrutinib Ixazomib 0 2
Ixazomib Ixazomib 3 2
Ixazomib + JQ1 Ixazomib JQ1 2 0
Ixazomib + Lenalidomide + Rituximab Ixazomib Lenalidomide Rituximab 0 1
Ixazomib + Rituximab Ixazomib Rituximab 0 2
Ixazomib + Romidepsin Ixazomib Romidepsin 0 1
Ixazomib + Selinexor Ixazomib Selinexor 0 1
Ixazomib + Vorinostat Ixazomib Vorinostat 1 1