Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Erdafitinib
Trade Name Balversa
Synonyms JNJ-42756493
Drug Descriptions

Balversa (erdafitinib) selectively inhibits FGFR1-4, resulting in decreased downstream signaling, and potentially leading to reduced growth of tumors with activated FGFR signaling (PMID: 28341788, PMID: 28965185). Balversa (erdafitinib) is FDA approved for use in patients with locally advanced or metastatic urothelial carcinoma with susceptible FGFR3 or FGFR2 genetic alterations (FDA.gov).

DrugClasses FGFR Inhibitor (Pan) 19
CAS Registry Number 1346242-81-6
NCIT ID C103273

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Erdafitinib Abiraterone Erdafitinib 0 1
Dexamethasone + Erdafitinib Dexamethasone Erdafitinib 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Enzalutamide + Erdafitinib Enzalutamide Erdafitinib 0 1
Erdafitinib Erdafitinib 83 11
Erdafitinib + Fulvestrant + Palbociclib Erdafitinib Fulvestrant Palbociclib 0 1
Erdafitinib + JNJ-63723283 Erdafitinib JNJ-63723283 0 1
Erdafitinib + Sapanisertib Erdafitinib Sapanisertib 2 0


Additional content available in CKB BOOST