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Drug Name Erdafitinib
Trade Name Balversa
Synonyms JNJ-42756493
Drug Descriptions

Balversa (erdafitinib) selectively inhibits FGFR1-4, resulting in decreased downstream signaling, and potentially leading to reduced growth of tumors with activated FGFR signaling (PMID: 28341788, PMID: 28965185). Balversa (erdafitinib) is FDA approved for use in patients with locally advanced or metastatic urothelial carcinoma with susceptible FGFR3 or FGFR2 genetic alterations (FDA.gov).

DrugClasses FGFR Inhibitor (Pan) 18

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Erdafitinib Abiraterone Erdafitinib 0 1
Dexamethasone + Erdafitinib Dexamethasone Erdafitinib 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Enzalutamide + Erdafitinib Enzalutamide Erdafitinib 0 1
Erdafitinib Erdafitinib 59 8
Erdafitinib + Fulvestrant + Palbociclib Erdafitinib Fulvestrant Palbociclib 0 1
Erdafitinib + JNJ-63723283 Erdafitinib JNJ-63723283 0 1
Erdafitinib + Sapanisertib Erdafitinib Sapanisertib 2 0


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