Drug Detail


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Drug Name Erdafitinib
Trade Name Balversa
Synonyms JNJ-42756493
Drug Descriptions

Balversa (erdafitinib) selectively inhibits FGFR1-4, resulting in decreased downstream signaling, and potentially leading to reduced growth of tumors with activated FGFR signaling (PMID: 28341788, PMID: 28965185). Balversa (erdafitinib) is FDA approved for use in patients with locally advanced or metastatic urothelial carcinoma with susceptible FGFR3 or FGFR2 genetic alterations (FDA.gov).

DrugClasses FGFR Inhibitor (Pan) 25
CAS Registry Number 1346242-81-6
NCIT ID C103273


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Erdafitinib Abiraterone Erdafitinib 0 1
Atezolizumab + Erdafitinib Atezolizumab Erdafitinib 0 1
Cetrelimab + Erdafitinib Cetrelimab Erdafitinib 2 1
Cetuximab + Erdafitinib + Sotorasib Cetuximab Erdafitinib Sotorasib 0 0
Dexamethasone + Erdafitinib Dexamethasone Erdafitinib 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Enfortumab vedotin-ejfv + Erdafitinib Enfortumab vedotin-ejfv Erdafitinib 0 1
Enzalutamide + Erdafitinib Enzalutamide Erdafitinib 0 1
Erdafitinib Erdafitinib 162 13
Erdafitinib + Erlotinib + Sotorasib Erdafitinib Erlotinib Sotorasib 0 0
Erdafitinib + Fulvestrant + Palbociclib Erdafitinib Fulvestrant Palbociclib 0 1
Erdafitinib + Gefitinib Erdafitinib Gefitinib 1 0
Erdafitinib + Osimertinib Erdafitinib Osimertinib 0 0
Erdafitinib + Osimertinib + Trametinib Erdafitinib Osimertinib Trametinib 0 0
Erdafitinib + Pictilisib Erdafitinib Pictilisib 1 0
Erdafitinib + Quisinostat Erdafitinib Quisinostat 1 0
Erdafitinib + Sapanisertib Erdafitinib Sapanisertib 0 0

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