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Drug Name Pomalidomide
Trade Name Pomalyst
Synonyms CC-4047
Drug Descriptions

Pomalyst (pomalidomide) is a thalidomide derivative that inhibits angiogenesis and modulates immune response, potentially lead to antitumor activity (PMID: 30069630). Pomalyst (pomalidomide) is FDA approved for use in patients with Kaposi's sarcoma who failed HAART or are HIV-negative, and in combination with dexamethasone in patients with multiple myeloma who had 2 or more prior therapies (FDA.gov).

DrugClasses
CAS Registry Number 19171-19-8
NCIT ID C72560

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Dexamethasone + Ixazomib + Pomalidomide Abemaciclib Dexamethasone Ixazomib Pomalidomide 0 1
APG-2575 + Dexamethasone + Pomalidomide APG-2575 Dexamethasone Pomalidomide 0 1
AR-42 + Dexamethasone + Pomalidomide AR-42 Dexamethasone Pomalidomide 0 1
belantamab mafodotin-blmf + Dexamethasone + Pomalidomide Dexamethasone Pomalidomide belantamab mafodotin-blmf 0 3
BMS-986207 + Dexamethasone + Pomalidomide BMS-986207 Dexamethasone Pomalidomide 0 1
Bortezomib + Ciltacabtagene autoleucel + Cyclophosphamide + Dexamethasone + Fludarabine + Pomalidomide Bortezomib Ciltacabtagene autoleucel Cyclophosphamide Dexamethasone Fludarabine Pomalidomide 0 1
Bortezomib + Dexamethasone + Idecabtagene Vicleucel + Pomalidomide Bortezomib Dexamethasone Idecabtagene Vicleucel Pomalidomide 0 1
Bortezomib + Dexamethasone + Pomalidomide Bortezomib Dexamethasone Pomalidomide 0 3
Carfilzomib + Daratumumab + Dexamethasone + Pomalidomide Carfilzomib Daratumumab Dexamethasone Pomalidomide 0 2
Carfilzomib + Dexamethasone + Elotuzumab + Pomalidomide Carfilzomib Dexamethasone Elotuzumab Pomalidomide 0 1
Carfilzomib + Dexamethasone + Isatuximab + Pomalidomide Carfilzomib Dexamethasone Isatuximab Pomalidomide 0 1
Carfilzomib + Dexamethasone + Pomalidomide Carfilzomib Dexamethasone Pomalidomide 0 1
Carfilzomib + Dexamethasone + Pomalidomide + Selinexor Carfilzomib Dexamethasone Pomalidomide Selinexor 0 1
Carfilzomib + Isatuximab + Pomalidomide Carfilzomib Isatuximab Pomalidomide 0 2
Ciltacabtagene autoleucel + Cyclophosphamide + Daratumumab + Dexamethasone + Fludarabine + Pomalidomide Ciltacabtagene autoleucel Cyclophosphamide Daratumumab Dexamethasone Fludarabine Pomalidomide 0 1
Citarinostat + Pomalidomide Citarinostat Pomalidomide 0 0
Clarithromycin + Daratumumab + Dexamethasone + Pomalidomide Clarithromycin Daratumumab Dexamethasone Pomalidomide 0 1
Clarithromycin + Dexamethasone + Pomalidomide + Selinexor Clarithromycin Dexamethasone Pomalidomide Selinexor 0 1
Cobimetinib + Dexamethasone + Ixazomib + Pomalidomide Cobimetinib Dexamethasone Ixazomib Pomalidomide 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Pomalidomide + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Pomalidomide Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Pomalidomide + Prednisone + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Pomalidomide Prednisone Vincristine Sulfate 0 1
Daratumumab + Dexamethasone + Durvalumab + Pomalidomide Daratumumab Dexamethasone Durvalumab Pomalidomide 0 1
Daratumumab + Dexamethasone + Ixazomib + Pomalidomide Daratumumab Dexamethasone Ixazomib Pomalidomide 0 1
Daratumumab + Dexamethasone + Pomalidomide Daratumumab Dexamethasone Pomalidomide 0 6
Daratumumab + Dexamethasone + Pomalidomide + Talquetamab Daratumumab Dexamethasone Pomalidomide Talquetamab 0 1
Daratumumab + Dexamethasone + Pomalidomide + Tazemetostat Daratumumab Dexamethasone Pomalidomide Tazemetostat 0 1
Daratumumab + Dexamethasone + Pomalidomide + Tretinoin Daratumumab Dexamethasone Pomalidomide Tretinoin 0 1
Daratumumab + Pomalidomide Daratumumab Pomalidomide 0 0
Daratumumab + Pomalidomide + Teclistamab Daratumumab Pomalidomide Teclistamab 0 1
Daratumumab and hyaluronidase-fihj + Dexamethasone + Pomalidomide Daratumumab and hyaluronidase-fihj Dexamethasone Pomalidomide 0 0
Daratumumab and hyaluronidase-fihj + Dexamethasone + Pomalidomide + Tazemetostat Daratumumab and hyaluronidase-fihj Dexamethasone Pomalidomide Tazemetostat 0 1
Dexamethasone + Elotuzumab + Isatuximab + Pomalidomide Dexamethasone Elotuzumab Isatuximab Pomalidomide 0 1
Dexamethasone + Elotuzumab + Nivolumab + Pomalidomide Dexamethasone Elotuzumab Nivolumab Pomalidomide 0 1
Dexamethasone + Elotuzumab + Pomalidomide Dexamethasone Elotuzumab Pomalidomide 0 5
Dexamethasone + Enasidenib + Ixazomib + Pomalidomide Dexamethasone Enasidenib Ixazomib Pomalidomide 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Dexamethasone + Everolimus + Pomalidomide Dexamethasone Everolimus Pomalidomide 0 1
Dexamethasone + Felzartamab + Pomalidomide Dexamethasone Felzartamab Pomalidomide 0 0
Dexamethasone + Filanesib + Pomalidomide Dexamethasone Filanesib Pomalidomide 0 0
Dexamethasone + Hu5F9-G4 + Pomalidomide Dexamethasone Hu5F9-G4 Pomalidomide 0 1
Dexamethasone + Isatuximab + Pomalidomide Dexamethasone Isatuximab Pomalidomide 0 5
Dexamethasone + Ixazomib + Pomalidomide + Venetoclax Dexamethasone Ixazomib Pomalidomide Venetoclax 0 1
Dexamethasone + LGH447 + Pomalidomide Dexamethasone LGH447 Pomalidomide 0 0
Dexamethasone + Marizomib + Pomalidomide Dexamethasone Marizomib Pomalidomide 0 0
Dexamethasone + Mezagitamab + Pomalidomide Dexamethasone Mezagitamab Pomalidomide 0 1
Dexamethasone + Nab-rapamycin + Pomalidomide Dexamethasone Nab-rapamycin Pomalidomide 0 1
Dexamethasone + Pembrolizumab + Pomalidomide Dexamethasone Pembrolizumab Pomalidomide 0 1
Dexamethasone + Pomalidomide Dexamethasone Pomalidomide 0 8
Dexamethasone + Pomalidomide + Relatlimab Dexamethasone Pomalidomide Relatlimab 0 1
Dexamethasone + Pomalidomide + Ricolinostat Dexamethasone Pomalidomide Ricolinostat 0 2
Dexamethasone + Pomalidomide + Selinexor Dexamethasone Pomalidomide Selinexor 0 4
Dexamethasone + Pomalidomide + TJ011133 Dexamethasone Pomalidomide TJ011133 0 1
Dexamethasone + Pomalidomide + TNB-383B Dexamethasone Pomalidomide TNB-383B 0 1
Dexamethasone + Pomalidomide + Venetoclax Dexamethasone Pomalidomide Venetoclax 0 1
DTRMWXHS-12 + Everolimus + Pomalidomide DTRMWXHS-12 Everolimus Pomalidomide 0 2
EED226 + Pomalidomide EED226 Pomalidomide 0 0
GSK126 + Pomalidomide GSK126 Pomalidomide 0 0
Nivolumab + Pomalidomide Nivolumab Pomalidomide 0 2
Pegylated liposomal-doxorubicin + Pomalidomide Pegylated liposomal-doxorubicin Pomalidomide 0 1
Pomalidomide Pomalidomide 0 7
Pomalidomide + Ruxolitinib Pomalidomide Ruxolitinib 0 1
Pomalidomide + SJB3-019A Pomalidomide SJB3-019A 0 0
Pomalidomide + Talquetamab Pomalidomide Talquetamab 0 1
Pomalidomide + TEW 7197 Pomalidomide TEW 7197 0 1
Pomalidomide + TK216 Pomalidomide TK216 0 0


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