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Drug Name Pomalidomide
Trade Name Pomalyst
Synonyms CC-4047
Drug Descriptions

Pomalyst (pomalidomide) is a thalidomide derivative that inhibits angiogenesis and modulates immune response, potentially lead to antitumor activity (PMID: 30069630). Pomalyst (pomalidomide) is FDA approved for use in patients with Kaposi's sarcoma who failed HAART or are HIV-negative, and in combination with dexamethasone in patients with multiple myeloma who had 2 or more prior therapies (FDA.gov).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Dexamethasone + Ixazomib + Pomalidomide Abemaciclib Dexamethasone Ixazomib Pomalidomide 0 1
AR-42 + Dexamethasone + Pomalidomide AR-42 Dexamethasone Pomalidomide 0 1
Belantamab mafodotin + Dexamethasone + Pomalidomide Belantamab mafodotin Dexamethasone Pomalidomide 0 1
BMS-986207 + Dexamethasone + Pomalidomide BMS-986207 Dexamethasone Pomalidomide 0 1
Bortezomib + Cyclophosphamide + Dexamethasone + Fludarabine + JNJ-68284528 + Pomalidomide Bortezomib Cyclophosphamide Dexamethasone Fludarabine JNJ-68284528 Pomalidomide 0 1
Bortezomib + Dexamethasone + Pomalidomide Bortezomib Dexamethasone Pomalidomide 0 2
Carfilzomib + Dexamethasone + Elotuzumab + Pomalidomide Carfilzomib Dexamethasone Elotuzumab Pomalidomide 0 1
Citarinostat + Pomalidomide Citarinostat Pomalidomide 1 0
Cobimetinib + Dexamethasone + Ixazomib + Pomalidomide Cobimetinib Dexamethasone Ixazomib Pomalidomide 0 1
Cyclophosphamide + Daratumumab + Dexamethasone + Fludarabine + JNJ-68284528 + Pomalidomide Cyclophosphamide Daratumumab Dexamethasone Fludarabine JNJ-68284528 Pomalidomide 0 1
Daratumumab + Dexamethasone + Durvalumab + Pomalidomide Daratumumab Dexamethasone Durvalumab Pomalidomide 0 1
Daratumumab + Dexamethasone + Ixazomib + Pomalidomide Daratumumab Dexamethasone Ixazomib Pomalidomide 0 1
Daratumumab + Dexamethasone + Pomalidomide Daratumumab Dexamethasone Pomalidomide 1 3
Dexamethasone + Elotuzumab + Nivolumab + Pomalidomide Dexamethasone Elotuzumab Nivolumab Pomalidomide 0 1
Dexamethasone + Elotuzumab + Pomalidomide Dexamethasone Elotuzumab Pomalidomide 0 4
Dexamethasone + Enasidenib + Ixazomib + Pomalidomide Dexamethasone Enasidenib Ixazomib Pomalidomide 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Dexamethasone + Everolimus + Pomalidomide Dexamethasone Everolimus Pomalidomide 0 1
Dexamethasone + Isatuximab + Pomalidomide Dexamethasone Isatuximab Pomalidomide 1 3
Dexamethasone + Ixazomib + Pomalidomide + Venetoclax Dexamethasone Ixazomib Pomalidomide Venetoclax 0 1
Dexamethasone + LGH447 + Pomalidomide Dexamethasone LGH447 Pomalidomide 0 0
Dexamethasone + Marizomib + Pomalidomide Dexamethasone Marizomib Pomalidomide 1 0
Dexamethasone + Nab-Rapamycin + Pomalidomide Dexamethasone Nab-Rapamycin Pomalidomide 0 1
Dexamethasone + Pembrolizumab + Pomalidomide Dexamethasone Pembrolizumab Pomalidomide 0 1
Dexamethasone + Pomalidomide Dexamethasone Pomalidomide 1 7
Dexamethasone + Pomalidomide + Relatlimab Dexamethasone Pomalidomide Relatlimab 0 1
Dexamethasone + Pomalidomide + Ricolinostat Dexamethasone Pomalidomide Ricolinostat 0 2
Dexamethasone + Pomalidomide + TAK-079 Dexamethasone Pomalidomide TAK-079 0 1
Dexamethasone + Pomalidomide + Venetoclax Dexamethasone Pomalidomide Venetoclax 0 1
DTRMWXHS-12 + Everolimus + Pomalidomide DTRMWXHS-12 Everolimus Pomalidomide 0 2
Nivolumab + Pomalidomide Nivolumab Pomalidomide 0 1
Pegylated liposomal-doxorubicin + Pomalidomide Pegylated liposomal-doxorubicin Pomalidomide 0 1
Pomalidomide Pomalidomide 1 7
Pomalidomide + SJB3-019A Pomalidomide SJB3-019A 1 0
Pomalidomide + TEW 7197 Pomalidomide TEW 7197 0 1


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