Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Talquetamab-tgvs
Trade Name Talvey
Synonyms JNJ64407564|JNJ 64407564|JNJ-64407564
Drug Descriptions

Talvey (talquetamab-tgvs) is a bispecific antibody that targets CD3 and GPRC5D, potentially resulting in increased immune response against GPRC5D-expressing tumor cells (PMID: 32040549). Talvey (talquetamab-tgvs) is FDA-approved for use in adult patients with relapsed or refractory multiple myeloma who have received four or more prior lines of therapy (FDA.gov).

DrugClasses CD3 Antibody 93
CAS Registry Number NA
NCIT ID C147534

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide + Talquetamab-tgvs + Teclistamab Bortezomib Daratumumab Dexamethasone Lenalidomide Talquetamab-tgvs Teclistamab 0 0
Carfilzomib + Daratumumab + Talquetamab-tgvs Carfilzomib Daratumumab Talquetamab-tgvs 0 1
Carfilzomib + Talquetamab-tgvs Carfilzomib Talquetamab-tgvs 0 1
Daratumumab + Dexamethasone + Pomalidomide + Talquetamab-tgvs Daratumumab Dexamethasone Pomalidomide Talquetamab-tgvs 0 1
Daratumumab + Dexamethasone + Talquetamab-tgvs Daratumumab Dexamethasone Talquetamab-tgvs 0 1
Daratumumab + Lenalidomide + Talquetamab-tgvs Daratumumab Lenalidomide Talquetamab-tgvs 0 1
Daratumumab + Talquetamab-tgvs Daratumumab Talquetamab-tgvs 0 3
Dexamethasone + Iberdomide + Talquetamab-tgvs Dexamethasone Iberdomide Talquetamab-tgvs 0 1
Lenalidomide + Talquetamab-tgvs Lenalidomide Talquetamab-tgvs 0 1
Pomalidomide + Talquetamab-tgvs Pomalidomide Talquetamab-tgvs 0 2
Talquetamab-tgvs Talquetamab-tgvs 0 5
Talquetamab-tgvs + Teclistamab Talquetamab-tgvs Teclistamab 0 3
Talquetamab-tgvs + Teclistamab + unspecified PD-1 antibody Talquetamab-tgvs Teclistamab unspecified PD-1 antibody 0 1


Additional content available in CKB BOOST