Drug Detail


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Drug Name Talquetamab-tgvs
Trade Name Talvey
Synonyms JNJ64407564|JNJ 64407564|JNJ-64407564
Drug Descriptions

Talvey (talquetamab-tgvs) is a bispecific antibody that targets CD3 and GPRC5D, potentially resulting in increased immune response against GPRC5D-expressing tumor cells (PMID: 32040549). Talvey (talquetamab-tgvs) is FDA-approved for use in adult patients with relapsed or refractory multiple myeloma who have received four or more prior lines of therapy (FDA.gov).

DrugClasses CD3 Antibody 93
CAS Registry Number NA
NCIT ID C147534


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide + Talquetamab-tgvs + Teclistamab Bortezomib Daratumumab Dexamethasone Lenalidomide Talquetamab-tgvs Teclistamab 0 0
Carfilzomib + Daratumumab + Talquetamab-tgvs Carfilzomib Daratumumab Talquetamab-tgvs 0 1
Carfilzomib + Talquetamab-tgvs Carfilzomib Talquetamab-tgvs 0 1
Daratumumab + Dexamethasone + Pomalidomide + Talquetamab-tgvs Daratumumab Dexamethasone Pomalidomide Talquetamab-tgvs 0 1
Daratumumab + Dexamethasone + Talquetamab-tgvs Daratumumab Dexamethasone Talquetamab-tgvs 0 1
Daratumumab + Lenalidomide + Talquetamab-tgvs Daratumumab Lenalidomide Talquetamab-tgvs 0 1
Daratumumab + Talquetamab-tgvs Daratumumab Talquetamab-tgvs 0 3
Dexamethasone + Iberdomide + Talquetamab-tgvs Dexamethasone Iberdomide Talquetamab-tgvs 0 1
Lenalidomide + Talquetamab-tgvs Lenalidomide Talquetamab-tgvs 0 1
Pomalidomide + Talquetamab-tgvs Pomalidomide Talquetamab-tgvs 0 2
Talquetamab-tgvs Talquetamab-tgvs 0 5
Talquetamab-tgvs + Teclistamab Talquetamab-tgvs Teclistamab 0 3
Talquetamab-tgvs + Teclistamab + unspecified PD-1 antibody Talquetamab-tgvs Teclistamab unspecified PD-1 antibody 0 1

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