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Drug Name Lenalidomide
Trade Name Revlimid
Synonyms IMiD-1
Drug Descriptions

Revlimid (lenalidomide) is a thalidomide analog which regulates cytokine production and stimulates T cells and NK cells activity (PMID: 24328678). Revlimid (lenalidomide) is FDA approved for use in multiple myeloma, relapsed or refractory Mantle cell lymphoma, and in combination with a rituximab product in follicular lymphoma and marginal zone lymphoma (FDA.gov).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Lenalidomide + Rituximab Acalabrutinib Lenalidomide Rituximab 0 2
AMG 701 + Lenalidomide AMG 701 Lenalidomide 1 0
Aspirin + Dexamethasone + Lenalidomide Aspirin Dexamethasone Lenalidomide 0 1
Atezolizumab + Lenalidomide + Obinutuzumab Atezolizumab Lenalidomide Obinutuzumab 0 1
Azacitidine + Dexamethasone + Lenalidomide + Romidepsin Azacitidine Dexamethasone Lenalidomide Romidepsin 0 1
belantamab mafodotin-blmf + Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 1
belantamab mafodotin-blmf + Dexamethasone + Lenalidomide Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 1
Bortezomib + Cyclophosphamide + Lenalidomide Bortezomib Cyclophosphamide Lenalidomide 0 1
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide Bortezomib Daratumumab Dexamethasone Lenalidomide 0 5
Bortezomib + Dexamethasone + Elotuzumab + Lenalidomide Bortezomib Dexamethasone Elotuzumab Lenalidomide 0 1
Bortezomib + Dexamethasone + Isatuximab + Lenalidomide Bortezomib Dexamethasone Isatuximab Lenalidomide 0 1
Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide 1 12
Bortezomib + Dexamethasone + Lenalidomide + Panobinostat Bortezomib Dexamethasone Lenalidomide Panobinostat 0 2
Bortezomib + Dexamethasone + Lenalidomide + TAK-079 Bortezomib Dexamethasone Lenalidomide TAK-079 0 1
Bortezomib + Lenalidomide Bortezomib Lenalidomide 0 1
Bortezomib + Lenalidomide + PAT-SM6 Bortezomib Lenalidomide PAT-SM6 0 0
Brentuximab vedotin + Lenalidomide Brentuximab vedotin Lenalidomide 0 1
BTCT4465A + Lenalidomide BTCT4465A Lenalidomide 0 1
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Rituximab Carboplatin Etoposide Ifosfamide Lenalidomide Rituximab 0 1
Carfilzomib + Daratumumab + Dexamethasone + Lenalidomide Carfilzomib Daratumumab Dexamethasone Lenalidomide 0 1
Carfilzomib + Dexamethasone + Elotuzumab + Lenalidomide Carfilzomib Dexamethasone Elotuzumab Lenalidomide 0 2
Carfilzomib + Dexamethasone + Isatuximab + Lenalidomide Carfilzomib Dexamethasone Isatuximab Lenalidomide 0 1
Carfilzomib + Dexamethasone + KRT-232 + Lenalidomide Carfilzomib Dexamethasone KRT-232 Lenalidomide 0 1
Carfilzomib + Dexamethasone + Lenalidomide Carfilzomib Dexamethasone Lenalidomide 0 2
Carfilzomib + Dexamethasone + Lenalidomide + Panobinostat Carfilzomib Dexamethasone Lenalidomide Panobinostat 0 1
Carfilzomib + Isatuximab + Lenalidomide Carfilzomib Isatuximab Lenalidomide 0 1
Carmustine + Cytarabine + Etoposide + Filgrastim + Lenalidomide + Melphalan + Rituximab Carmustine Cytarabine Etoposide Filgrastim Lenalidomide Melphalan Rituximab 0 1
Cediranib + Lenalidomide Cediranib Lenalidomide 0 1
Cetuximab + Lenalidomide Cetuximab Lenalidomide 0 0
CS1-CAR T cells + Lenalidomide CS1-CAR T cells Lenalidomide 0 0
Cyclophosphamide + Dexamethasone + Lenalidomide Cyclophosphamide Dexamethasone Lenalidomide 1 0
Cyclophosphamide + Doxorubicin + Durvalumab + Lenalidomide + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Durvalumab Lenalidomide Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Lenalidomide + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Cyclophosphamide Doxorubicin Lenalidomide Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 1
Cyclophosphamide + Fludarabine + KTE-C19 + Lenalidomide Cyclophosphamide Fludarabine KTE-C19 Lenalidomide 0 1
Daratumumab + Dexamethasone + Lenalidomide Daratumumab Dexamethasone Lenalidomide 2 5
Daratumumab + Lenalidomide Daratumumab Lenalidomide 0 4
Daratumumab + Lenalidomide + rHuPH20 Daratumumab Lenalidomide rHuPH20 0 1
Daratumumab and hyaluronidase-fihj + Dexamethasone + Lenalidomide Daratumumab and hyaluronidase-fihj Dexamethasone Lenalidomide 1 0
Dasatinib + Lenalidomide Dasatinib Lenalidomide 0 1
Dexamethasone + Elotuzumab + Lenalidomide Dexamethasone Elotuzumab Lenalidomide 1 4
Dexamethasone + Ibrutinib + Lenalidomide Dexamethasone Ibrutinib Lenalidomide 0 2
Dexamethasone + Isatuximab + Lenalidomide Dexamethasone Isatuximab Lenalidomide 0 1
Dexamethasone + Ixazomib + Lenalidomide Dexamethasone Ixazomib Lenalidomide 1 2
Dexamethasone + Ixazomib + Lenalidomide + Tasquinimod Dexamethasone Ixazomib Lenalidomide Tasquinimod 0 1
Dexamethasone + Lenalidomide Dexamethasone Lenalidomide 0 3
Dexamethasone + Lenalidomide + LGH447 Dexamethasone LGH447 Lenalidomide 0 0
Dexamethasone + Lenalidomide + Nivolumab Dexamethasone Lenalidomide Nivolumab 0 1
Dexamethasone + Lenalidomide + PAT-SM6 Dexamethasone Lenalidomide PAT-SM6 0 0
Dexamethasone + Lenalidomide + Pembrolizumab Dexamethasone Lenalidomide Pembrolizumab 0 1
Dexamethasone + Lenalidomide + Ricolinostat Dexamethasone Lenalidomide Ricolinostat 1 0
Dexamethasone + Lenalidomide + Rivaroxaban Dexamethasone Lenalidomide Rivaroxaban 0 1
Dexamethasone + Lenalidomide + TAK-079 Dexamethasone Lenalidomide TAK-079 0 1
Dexamethasone + Lenalidomide + Ulocuplumab Dexamethasone Lenalidomide Ulocuplumab 1 1
Dexamethasone + Lenalidomide + Venetoclax Dexamethasone Lenalidomide Venetoclax 0 1
Durvalumab + Lenalidomide Durvalumab Lenalidomide 0 2
Durvalumab + Lenalidomide + PVX-410 Durvalumab Lenalidomide PVX-410 0 1
Durvalumab + Lenalidomide + Rituximab Durvalumab Lenalidomide Rituximab 0 1
Elotuzumab + Lenalidomide Elotuzumab Lenalidomide 0 4
Felzartamab + Lenalidomide Felzartamab Lenalidomide 0 0
Felzartamab + Lenalidomide + Vitamin D Felzartamab Lenalidomide Vitamin D 0 0
Fludarabine + Lenalidomide + Melphalan Fludarabine Lenalidomide Melphalan 0 1
GSK126 + Lenalidomide GSK126 Lenalidomide 1 0
Ibrutinib + Lenalidomide Ibrutinib Lenalidomide 0 3
Ibrutinib + Lenalidomide + Obinutuzumab + Prednisone + Venetoclax Ibrutinib Lenalidomide Obinutuzumab Prednisone Venetoclax 0 1
Ibrutinib + Lenalidomide + Rituximab Ibrutinib Lenalidomide Rituximab 0 8
Ipilimumab + Lenalidomide Ipilimumab Lenalidomide 0 2
Ixazomib + Lenalidomide + Rituximab Ixazomib Lenalidomide Rituximab 0 1
Lenalidomide Lenalidomide 3 29
Lenalidomide + Methylprednisolone + Ruxolitinib Lenalidomide Methylprednisolone Ruxolitinib 0 1
Lenalidomide + Mivavotinib Lenalidomide Mivavotinib 0 1
Lenalidomide + Montanide ISA 51 + Sargramostim + SurVaxM Lenalidomide Montanide ISA 51 Sargramostim SurVaxM 0 1
Lenalidomide + MT-3724 Lenalidomide MT-3724 0 1
Lenalidomide + Nivolumab Lenalidomide Nivolumab 0 2
Lenalidomide + Nivolumab + Rituximab Lenalidomide Nivolumab Rituximab 0 1
Lenalidomide + Obinutuzumab Lenalidomide Obinutuzumab 0 2
Lenalidomide + Obinutuzumab + Polatuzumab vedotin-piiq Lenalidomide Obinutuzumab Polatuzumab vedotin-piiq 0 1
Lenalidomide + Obinutuzumab + RO7082859 Lenalidomide Obinutuzumab RO7082859 0 1
Lenalidomide + Obinutuzumab + Venetoclax Lenalidomide Obinutuzumab Venetoclax 0 2
Lenalidomide + Ofatumumab Lenalidomide Ofatumumab 1 0
Lenalidomide + PAT-SM6 Lenalidomide PAT-SM6 0 0
Lenalidomide + Pembrolizumab Lenalidomide Pembrolizumab 0 3
Lenalidomide + Pidilizumab Lenalidomide Pidilizumab 0 1
Lenalidomide + Polatuzumab vedotin-piiq + Rituximab Lenalidomide Polatuzumab vedotin-piiq Rituximab 0 1
Lenalidomide + PVX-410 Lenalidomide PVX-410 1 0
Lenalidomide + Rituximab Lenalidomide Rituximab 2 2
Lenalidomide + Rituximab + Romidepsin Lenalidomide Rituximab Romidepsin 0 1
Lenalidomide + Rituximab + Tazemetostat Lenalidomide Rituximab Tazemetostat 0 1
Lenalidomide + Rituximab + Thalidomide Lenalidomide Rituximab Thalidomide 0 1
Lenalidomide + Rituximab + Venetoclax Lenalidomide Rituximab Venetoclax 0 2
Lenalidomide + Rituximab Hyaluronidase + Venetoclax Lenalidomide Rituximab Hyaluronidase Venetoclax 0 1
Lenalidomide + RO7082859 Lenalidomide RO7082859 0 1
Lenalidomide + Romidepsin Lenalidomide Romidepsin 0 1
Lenalidomide + Selinexor Lenalidomide Selinexor 0 1
Lenalidomide + SJB3-019A Lenalidomide SJB3-019A 1 0
Lenalidomide + Sonidegib Lenalidomide Sonidegib 0 1
Lenalidomide + Sorafenib Lenalidomide Sorafenib 1 0
Lenalidomide + Tafasitamab-cxix Lenalidomide Tafasitamab-cxix 1 2
Lenalidomide + Temsirolimus Lenalidomide Temsirolimus 0 1
Lenalidomide + Vorinostat Lenalidomide Vorinostat 0 1


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