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Drug Name Lenalidomide
Trade Name Revlimid
Synonyms IMiD-1
Drug Descriptions

Revlimid (lenalidomide) is a thalidomide analog which regulates cytokine production and stimulates T cells and NK cells activity (PMID: 24328678). Revlimid (lenalidomide) is FDA approved for use in multiple myeloma, relapsed or refractory Mantle cell lymphoma, and in combination with a rituximab product in follicular lymphoma and marginal zone lymphoma (FDA.gov).

DrugClasses
CAS Registry Number 191732-72-6
NCIT ID C2668

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-383 + Dexamethasone + Lenalidomide ABBV-383 Dexamethasone Lenalidomide 0 1
Acalabrutinib + Cyclophosphamide + Doxorubicin + Lenalidomide + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Acalabrutinib Cyclophosphamide Doxorubicin Lenalidomide Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 1
Acalabrutinib + Lenalidomide + Rituximab Acalabrutinib Lenalidomide Rituximab 0 2
Acalabrutinib + Lenalidomide + Rituximab + Tafasitamab-cxix Acalabrutinib Lenalidomide Rituximab Tafasitamab-cxix 0 1
AMG 701 + Lenalidomide AMG 701 Lenalidomide 0 0
ANV419 + Dexamethasone + Lenalidomide ANV419 Dexamethasone Lenalidomide 0 1
APG-2575 + Daratumumab + Dexamethasone + Lenalidomide APG-2575 Daratumumab Dexamethasone Lenalidomide 0 1
APG-2575 + Dexamethasone + Lenalidomide APG-2575 Dexamethasone Lenalidomide 0 1
Aspirin + Dexamethasone + Lenalidomide Aspirin Dexamethasone Lenalidomide 0 1
Atezolizumab + Lenalidomide + Obinutuzumab Atezolizumab Lenalidomide Obinutuzumab 0 1
axicabtagene ciloleucel + Cyclophosphamide + Fludarabine + Lenalidomide Cyclophosphamide Fludarabine Lenalidomide axicabtagene ciloleucel 0 0
Azacitidine + Dexamethasone + Lenalidomide + Romidepsin Azacitidine Dexamethasone Lenalidomide Romidepsin 0 1
Azacitidine + Lenalidomide + Obinutuzumab Azacitidine Lenalidomide Obinutuzumab 0 1
Belantamab + belantamab mafodotin-blmf + Dexamethasone + Lenalidomide Belantamab Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 1
belantamab mafodotin-blmf + Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 2
belantamab mafodotin-blmf + Carfilzomib + Dexamethasone + Lenalidomide Carfilzomib Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 1
belantamab mafodotin-blmf + Daratumumab + Dexamethasone + Lenalidomide Daratumumab Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 2
belantamab mafodotin-blmf + Daratumumab + Lenalidomide Daratumumab Lenalidomide belantamab mafodotin-blmf 0 1
belantamab mafodotin-blmf + Dexamethasone + Lenalidomide Dexamethasone Lenalidomide belantamab mafodotin-blmf 0 1
belantamab mafodotin-blmf + Lenalidomide Lenalidomide belantamab mafodotin-blmf 0 1
Bortezomib + Cyclophosphamide + Lenalidomide Bortezomib Cyclophosphamide Lenalidomide 0 1
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide Bortezomib Daratumumab Dexamethasone Lenalidomide 0 13
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide + Talquetamab-tgvs + Teclistamab Bortezomib Daratumumab Dexamethasone Lenalidomide Talquetamab-tgvs Teclistamab 0 0
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide + Teclistamab Bortezomib Daratumumab Dexamethasone Lenalidomide Teclistamab 0 1
Bortezomib + Daratumumab + Lenalidomide + Teclistamab Bortezomib Daratumumab Lenalidomide Teclistamab 0 1
Bortezomib + Daratumumab and hyaluronidase-fihj + Dexamethasone + Lenalidomide Bortezomib Daratumumab and hyaluronidase-fihj Dexamethasone Lenalidomide 0 1
Bortezomib + Dexamethasone + Elotuzumab + Lenalidomide Bortezomib Dexamethasone Elotuzumab Lenalidomide 0 1
Bortezomib + Dexamethasone + Iberdomide + Isatuximab + Lenalidomide Bortezomib Dexamethasone Iberdomide Isatuximab Lenalidomide 0 1
Bortezomib + Dexamethasone + Isatuximab + Lenalidomide Bortezomib Dexamethasone Isatuximab Lenalidomide 0 6
Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide 0 16
Bortezomib + Dexamethasone + Lenalidomide + Melphalan + Prednisone Bortezomib Dexamethasone Lenalidomide Melphalan Prednisone 0 1
Bortezomib + Dexamethasone + Lenalidomide + Mezagitamab Bortezomib Dexamethasone Lenalidomide Mezagitamab 0 1
Bortezomib + Dexamethasone + Lenalidomide + Panobinostat Bortezomib Dexamethasone Lenalidomide Panobinostat 0 2
Bortezomib + Lenalidomide Bortezomib Lenalidomide 0 1
Bortezomib + Lenalidomide + PAT-SM6 Bortezomib Lenalidomide PAT-SM6 0 0
Bortezomib + Lenalidomide + Rituximab Bortezomib Lenalidomide Rituximab 0 1
Brentuximab vedotin + Lenalidomide Brentuximab vedotin Lenalidomide 0 1
Brentuximab vedotin + Lenalidomide + Rituximab Brentuximab vedotin Lenalidomide Rituximab 0 1
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Rituximab Carboplatin Etoposide Ifosfamide Lenalidomide Rituximab 0 1
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Tafasitamab-cxix Carboplatin Etoposide Ifosfamide Lenalidomide Tafasitamab-cxix 0 1
Carfilzomib + Daratumumab + Dexamethasone + Lenalidomide Carfilzomib Daratumumab Dexamethasone Lenalidomide 0 6
Carfilzomib + Daratumumab + Lenalidomide Carfilzomib Daratumumab Lenalidomide 0 1
Carfilzomib + Dexamethasone + Elotuzumab + Lenalidomide Carfilzomib Dexamethasone Elotuzumab Lenalidomide 0 3
Carfilzomib + Dexamethasone + Isatuximab + Lenalidomide Carfilzomib Dexamethasone Isatuximab Lenalidomide 0 4
Carfilzomib + Dexamethasone + KRT-232 + Lenalidomide Carfilzomib Dexamethasone KRT-232 Lenalidomide 0 1
Carfilzomib + Dexamethasone + Lenalidomide Carfilzomib Dexamethasone Lenalidomide 0 8
Carfilzomib + Dexamethasone + Lenalidomide + Panobinostat Carfilzomib Dexamethasone Lenalidomide Panobinostat 0 1
Carfilzomib + Isatuximab + Lenalidomide Carfilzomib Isatuximab Lenalidomide 0 1
Carmustine + Cytarabine + Etoposide + Filgrastim + Lenalidomide + Melphalan + Rituximab Carmustine Cytarabine Etoposide Filgrastim Lenalidomide Melphalan Rituximab 0 1
Cediranib + Lenalidomide Cediranib Lenalidomide 0 1
Cetuximab + Lenalidomide Cetuximab Lenalidomide 0 0
Cevostamab + Lenalidomide + Tocilizumab Cevostamab Lenalidomide Tocilizumab 0 1
CS1-CAR T cells + Lenalidomide CS1-CAR T cells Lenalidomide 0 0
Cyclophosphamide + Dexamethasone + Lenalidomide Cyclophosphamide Dexamethasone Lenalidomide 0 0
Cyclophosphamide + Doxorubicin + Durvalumab + Lenalidomide + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Durvalumab Lenalidomide Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Lenalidomide + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Lenalidomide Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Lenalidomide + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Cyclophosphamide Doxorubicin Lenalidomide Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 2
Cyclophosphamide + Fludarabine + Idecabtagene Vicleucel + Lenalidomide Cyclophosphamide Fludarabine Idecabtagene Vicleucel Lenalidomide 0 1
Daratumumab + Dexamethasone + Ixazomib + Lenalidomide Daratumumab Dexamethasone Ixazomib Lenalidomide 0 2
Daratumumab + Dexamethasone + Lenalidomide Daratumumab Dexamethasone Lenalidomide 0 12
Daratumumab + Dexamethasone + Lenalidomide + Selinexor Daratumumab Dexamethasone Lenalidomide Selinexor 0 1
Daratumumab + Dexamethasone + Lenalidomide + Teclistamab Daratumumab Dexamethasone Lenalidomide Teclistamab 0 1
Daratumumab + Dexamethasone + Lenalidomide + Venetoclax Daratumumab Dexamethasone Lenalidomide Venetoclax 0 1
Daratumumab + Elranatamab-bcmm + Lenalidomide Daratumumab Elranatamab-bcmm Lenalidomide 0 1
Daratumumab + Lenalidomide Daratumumab Lenalidomide 0 7
Daratumumab + Lenalidomide + rHuPH20 Daratumumab Lenalidomide rHuPH20 0 1
Daratumumab + Lenalidomide + Talquetamab-tgvs Daratumumab Lenalidomide Talquetamab-tgvs 0 1
Daratumumab + Lenalidomide + Teclistamab Daratumumab Lenalidomide Teclistamab 0 2
Daratumumab and hyaluronidase-fihj + Dexamethasone + Lenalidomide Daratumumab and hyaluronidase-fihj Dexamethasone Lenalidomide 0 1
Dasatinib + Lenalidomide Dasatinib Lenalidomide 0 1
Dexamethasone + Elotuzumab + Lenalidomide Dexamethasone Elotuzumab Lenalidomide 0 5
Dexamethasone + Felzartamab + Lenalidomide Dexamethasone Felzartamab Lenalidomide 0 0
Dexamethasone + Ibrutinib + Lenalidomide Dexamethasone Ibrutinib Lenalidomide 0 2
Dexamethasone + Isatuximab + Lenalidomide Dexamethasone Isatuximab Lenalidomide 0 6
Dexamethasone + Ixazomib + Lenalidomide Dexamethasone Ixazomib Lenalidomide 0 3
Dexamethasone + Ixazomib + Lenalidomide + Tasquinimod Dexamethasone Ixazomib Lenalidomide Tasquinimod 0 1
Dexamethasone + Lenalidomide Dexamethasone Lenalidomide 0 9
Dexamethasone + Lenalidomide + LGH447 Dexamethasone LGH447 Lenalidomide 0 0
Dexamethasone + Lenalidomide + Linvoseltamab Dexamethasone Lenalidomide Linvoseltamab 0 1
Dexamethasone + Lenalidomide + Mezagitamab Dexamethasone Lenalidomide Mezagitamab 0 1
Dexamethasone + Lenalidomide + Nivolumab Dexamethasone Lenalidomide Nivolumab 0 1
Dexamethasone + Lenalidomide + PAT-SM6 Dexamethasone Lenalidomide PAT-SM6 0 0
Dexamethasone + Lenalidomide + Pembrolizumab Dexamethasone Lenalidomide Pembrolizumab 0 1
Dexamethasone + Lenalidomide + Ricolinostat Dexamethasone Lenalidomide Ricolinostat 0 0
Dexamethasone + Lenalidomide + Rivaroxaban Dexamethasone Lenalidomide Rivaroxaban 0 1
Dexamethasone + Lenalidomide + Selinexor Dexamethasone Lenalidomide Selinexor 0 1
Dexamethasone + Lenalidomide + Ulocuplumab Dexamethasone Lenalidomide Ulocuplumab 0 1
Dexamethasone + Lenalidomide + Venetoclax Dexamethasone Lenalidomide Venetoclax 0 2
Dinutuximab + Lenalidomide Dinutuximab Lenalidomide 0 1
DS-3201b + Lenalidomide + Rituximab DS-3201b Lenalidomide Rituximab 0 1
Durvalumab + Lenalidomide Durvalumab Lenalidomide 0 3
Durvalumab + Lenalidomide + PVX-410 Durvalumab Lenalidomide PVX-410 0 1
Durvalumab + Lenalidomide + Rituximab Durvalumab Lenalidomide Rituximab 0 1
Elotuzumab + Lenalidomide Elotuzumab Lenalidomide 0 4
EO2463 + Lenalidomide + Rituximab EO2463 Lenalidomide Rituximab 0 1
Epcoritamab-bysp + Ibrutinib + Lenalidomide Epcoritamab-bysp Ibrutinib Lenalidomide 0 1
Epcoritamab-bysp + Lenalidomide Epcoritamab-bysp Lenalidomide 0 6
Epcoritamab-bysp + Lenalidomide + Rituximab Epcoritamab-bysp Lenalidomide Rituximab 0 3
Evorpacept + Lenalidomide + Rituximab Evorpacept Lenalidomide Rituximab 0 1
Felzartamab + Lenalidomide Felzartamab Lenalidomide 0 0
Felzartamab + Lenalidomide + Vitamin D Felzartamab Lenalidomide Vitamin D 0 0
Fludarabine + Lenalidomide + Melphalan Fludarabine Lenalidomide Melphalan 0 1
Glofitamab-gxbm + Lenalidomide Glofitamab-gxbm Lenalidomide 0 0
Glofitamab-gxbm + Lenalidomide + Obinutuzumab Glofitamab-gxbm Lenalidomide Obinutuzumab 0 1
Glofitamab-gxbm + Lenalidomide + Obinutuzumab + Venetoclax Glofitamab-gxbm Lenalidomide Obinutuzumab Venetoclax 0 1
GSK126 + Lenalidomide GSK126 Lenalidomide 0 0
Iberdomide + Lenalidomide + Tafasitamab-cxix Iberdomide Lenalidomide Tafasitamab-cxix 0 0
Ibrutinib + Lenalidomide Ibrutinib Lenalidomide 0 3
Ibrutinib + Lenalidomide + Obinutuzumab + Polatuzumab vedotin-piiq + Prednisone + Venetoclax Ibrutinib Lenalidomide Obinutuzumab Polatuzumab vedotin-piiq Prednisone Venetoclax 0 1
Ibrutinib + Lenalidomide + Obinutuzumab + Prednisone + Venetoclax Ibrutinib Lenalidomide Obinutuzumab Prednisone Venetoclax 0 2
Ibrutinib + Lenalidomide + Rituximab Ibrutinib Lenalidomide Rituximab 0 8
Idecabtagene Vicleucel + Lenalidomide Idecabtagene Vicleucel Lenalidomide 0 1
Ipilimumab + Lenalidomide Ipilimumab Lenalidomide 0 2
Isatuximab + Lenalidomide Isatuximab Lenalidomide 0 2
Ixazomib + Lenalidomide + Rituximab Ixazomib Lenalidomide Rituximab 0 1
Lenalidomide Lenalidomide 0 38
Lenalidomide + Loncastuximab tesirine-lpyl Lenalidomide Loncastuximab tesirine-lpyl 0 1
Lenalidomide + Methotrexate + Nivolumab + Rituximab Lenalidomide Methotrexate Nivolumab Rituximab 0 1
Lenalidomide + Methotrexate + Procarbazine + Rituximab Lenalidomide Methotrexate Procarbazine Rituximab 0 1
Lenalidomide + Methotrexate + Rituximab + Tafasitamab-cxix Lenalidomide Methotrexate Rituximab Tafasitamab-cxix 0 1
Lenalidomide + Methylprednisolone + Ruxolitinib Lenalidomide Methylprednisolone Ruxolitinib 0 1
Lenalidomide + Mivavotinib Lenalidomide Mivavotinib 0 1
Lenalidomide + Montanide ISA 51 + Sargramostim + SurVaxM Lenalidomide Montanide ISA 51 Sargramostim SurVaxM 0 1
Lenalidomide + Mosunetuzumab-axgb Lenalidomide Mosunetuzumab-axgb 0 4
Lenalidomide + Mosunetuzumab-axgb + Polatuzumab vedotin-piiq Lenalidomide Mosunetuzumab-axgb Polatuzumab vedotin-piiq 0 1
Lenalidomide + Mosunetuzumab-axgb + Polatuzumab vedotin-piiq + Tafasitamab-cxix Lenalidomide Mosunetuzumab-axgb Polatuzumab vedotin-piiq Tafasitamab-cxix 0 1
Lenalidomide + Mosunetuzumab-axgb + Tocilizumab Lenalidomide Mosunetuzumab-axgb Tocilizumab 0 1
Lenalidomide + MT-3724 Lenalidomide MT-3724 0 1
Lenalidomide + Nivolumab Lenalidomide Nivolumab 0 4
Lenalidomide + Nivolumab + Rituximab Lenalidomide Nivolumab Rituximab 0 1
Lenalidomide + Obinutuzumab Lenalidomide Obinutuzumab 0 2
Lenalidomide + Obinutuzumab + Polatuzumab vedotin-piiq Lenalidomide Obinutuzumab Polatuzumab vedotin-piiq 0 1
Lenalidomide + Obinutuzumab + Venetoclax Lenalidomide Obinutuzumab Venetoclax 0 2
Lenalidomide + Odronextamab Lenalidomide Odronextamab 0 1
Lenalidomide + Ofatumumab Lenalidomide Ofatumumab 0 0
Lenalidomide + OT-A201 Lenalidomide OT-A201 0 1
Lenalidomide + PAT-SM6 Lenalidomide PAT-SM6 0 0
Lenalidomide + Pembrolizumab Lenalidomide Pembrolizumab 0 3
Lenalidomide + Pidilizumab Lenalidomide Pidilizumab 0 1
Lenalidomide + Polatuzumab vedotin-piiq + Rituximab Lenalidomide Polatuzumab vedotin-piiq Rituximab 0 1
Lenalidomide + PVX-410 Lenalidomide PVX-410 0 0
Lenalidomide + Rituximab Lenalidomide Rituximab 2 14
Lenalidomide + Rituximab + Romidepsin Lenalidomide Rituximab Romidepsin 0 1
Lenalidomide + Rituximab + Selinexor Lenalidomide Rituximab Selinexor 0 1
Lenalidomide + Rituximab + Tafasitamab-cxix Lenalidomide Rituximab Tafasitamab-cxix 0 2
Lenalidomide + Rituximab + Tazemetostat Lenalidomide Rituximab Tazemetostat 0 1
Lenalidomide + Rituximab + Thalidomide Lenalidomide Rituximab Thalidomide 0 1
Lenalidomide + Rituximab + Tocilizumab Lenalidomide Rituximab Tocilizumab 0 1
Lenalidomide + Rituximab + Venetoclax Lenalidomide Rituximab Venetoclax 0 2
Lenalidomide + Rituximab Hyaluronidase + Venetoclax Lenalidomide Rituximab Hyaluronidase Venetoclax 0 1
Lenalidomide + Romidepsin Lenalidomide Romidepsin 0 1
Lenalidomide + Selinexor Lenalidomide Selinexor 0 2
Lenalidomide + Selinexor + Tafasitamab-cxix Lenalidomide Selinexor Tafasitamab-cxix 0 1
Lenalidomide + SJB3-019A Lenalidomide SJB3-019A 0 0
Lenalidomide + Sonidegib Lenalidomide Sonidegib 0 1
Lenalidomide + Sorafenib Lenalidomide Sorafenib 0 0
Lenalidomide + Tafasitamab-cxix Lenalidomide Tafasitamab-cxix 0 9
Lenalidomide + Tafasitamab-cxix + Tazemetostat Lenalidomide Tafasitamab-cxix Tazemetostat 0 2
Lenalidomide + Tafasitamab-cxix + Temozolomide Lenalidomide Tafasitamab-cxix Temozolomide 0 0
Lenalidomide + Tafasitamab-cxix + TTI-622 Lenalidomide TTI-622 Tafasitamab-cxix 0 1
Lenalidomide + Tafasitamab-cxix + Venetoclax Lenalidomide Tafasitamab-cxix Venetoclax 0 1
Lenalidomide + Tafasitamab-cxix + XmAb13676 Lenalidomide Tafasitamab-cxix XmAb13676 0 1
Lenalidomide + Tafasitamab-cxix + Zanubrutinib Lenalidomide Tafasitamab-cxix Zanubrutinib 0 1
Lenalidomide + TAK-573 Lenalidomide TAK-573 0 1
Lenalidomide + Talquetamab-tgvs Lenalidomide Talquetamab-tgvs 0 1
Lenalidomide + Tazemetostat Lenalidomide Tazemetostat 0 1
Lenalidomide + Teclistamab Lenalidomide Teclistamab 0 2
Lenalidomide + Temsirolimus Lenalidomide Temsirolimus 0 1
Lenalidomide + TK216 Lenalidomide TK216 0 0
Lenalidomide + Ublituximab + Umbralisib Lenalidomide Ublituximab Umbralisib 0 1
Lenalidomide + VAY736 Lenalidomide VAY736 0 1
Lenalidomide + Vorinostat Lenalidomide Vorinostat 0 1
Lenalidomide + VP301 Lenalidomide VP301 0 0
Lenalidomide + YK-4-279 Lenalidomide YK-4-279 0 0


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