Drug Detail

Drug Name Lenalidomide
Trade Name Revlimid
Synonyms IMiD-1
Drug Descriptions

Revlimid (lenalidomide) is a thalidomide analog which regulates cytokine production and stimulates T cells and NK cells activity (PMID: 24328678). Revlimid (lenalidomide) is FDA approved for use in multiple myeloma, relapsed or refractory Mantle cell lymphoma, and in combination with a rituximab product in follicular lymphoma and marginal zone lymphoma (FDA.gov).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Lenalidomide + Rituximab Acalabrutinib Lenalidomide Rituximab 0 1
AMG 232 + Carfilzomib + Dexamethasone + Lenalidomide AMG 232 Carfilzomib Dexamethasone Lenalidomide 0 1
Atezolizumab + Lenalidomide + Obinutuzumab Atezolizumab Lenalidomide Obinutuzumab 0 1
Bortezomib + Cyclophosphamide + Lenalidomide Bortezomib Cyclophosphamide Lenalidomide 0 1
Bortezomib + Daratumumab + Dexamethasone + Lenalidomide Bortezomib Daratumumab Dexamethasone Lenalidomide 0 2
Bortezomib + Dexamethasone + Elotuzumab + Lenalidomide Bortezomib Dexamethasone Elotuzumab Lenalidomide 0 1
Bortezomib + Dexamethasone + Isatuximab + Lenalidomide Bortezomib Dexamethasone Isatuximab Lenalidomide 0 1
Bortezomib + Dexamethasone + Lenalidomide Bortezomib Dexamethasone Lenalidomide 1 10
Bortezomib + Dexamethasone + Lenalidomide + Panobinostat Bortezomib Dexamethasone Lenalidomide Panobinostat 0 2
Bortezomib + Lenalidomide Bortezomib Lenalidomide 0 1
Bortezomib + Lenalidomide + PAT-SM6 Bortezomib Lenalidomide PAT-SM6 0 0
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Rituximab Carboplatin Etoposide Ifosfamide Lenalidomide Rituximab 0 1
Carfilzomib + Dexamethasone + Elotuzumab + Lenalidomide Carfilzomib Dexamethasone Elotuzumab Lenalidomide 0 2
Carfilzomib + Dexamethasone + Lenalidomide Carfilzomib Dexamethasone Lenalidomide 0 1
Carfilzomib + Dexamethasone + Lenalidomide + Panobinostat Carfilzomib Dexamethasone Lenalidomide Panobinostat 0 1
Carmustine + Cytarabine + Etoposide + Filgrastim + Lenalidomide + Melphalan + Rituximab Carmustine Cytarabine Etoposide Filgrastim Lenalidomide Melphalan Rituximab 0 1
Cediranib + Lenalidomide Cediranib Lenalidomide 0 1
Cetuximab + Lenalidomide Cetuximab Lenalidomide 0 0
Cyclophosphamide + Dexamethasone + Lenalidomide Cyclophosphamide Dexamethasone Lenalidomide 1 0
Cyclophosphamide + Doxorubicin + Durvalumab + Lenalidomide + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Durvalumab Lenalidomide Prednisone Rituximab Vincristine 0 1
Daratumumab + Dexamethasone + Lenalidomide Daratumumab Dexamethasone Lenalidomide 2 2
Dasatinib + Lenalidomide Dasatinib Lenalidomide 0 1
Dexamethasone + Elotuzumab + Lenalidomide Dexamethasone Elotuzumab Lenalidomide 1 4
Dexamethasone + GSK2857916 + Lenalidomide Dexamethasone GSK2857916 Lenalidomide 0 1
Dexamethasone + Ibrutinib + Lenalidomide Dexamethasone Ibrutinib Lenalidomide 0 1
Dexamethasone + Isatuximab + Lenalidomide Dexamethasone Isatuximab Lenalidomide 0 1
Dexamethasone + Ixazomib + Lenalidomide Dexamethasone Ixazomib Lenalidomide 0 2
Dexamethasone + Lenalidomide Dexamethasone Lenalidomide 0 2
Dexamethasone + Lenalidomide + LGH447 Dexamethasone LGH447 Lenalidomide 0 0
Dexamethasone + Lenalidomide + Nivolumab Dexamethasone Lenalidomide Nivolumab 0 1
Dexamethasone + Lenalidomide + PAT-SM6 Dexamethasone Lenalidomide PAT-SM6 0 0
Dexamethasone + Lenalidomide + Pembrolizumab Dexamethasone Lenalidomide Pembrolizumab 0 1
Dexamethasone + Lenalidomide + Ricolinostat Dexamethasone Lenalidomide Ricolinostat 1 0
Dexamethasone + Lenalidomide + Ulocuplumab Dexamethasone Lenalidomide Ulocuplumab 0 1
Dexamethasone + Lenalidomide + Venetoclax Dexamethasone Lenalidomide Venetoclax 0 1
Durvalumab + Lenalidomide Durvalumab Lenalidomide 0 2
Durvalumab + Lenalidomide + PVX-410 Durvalumab Lenalidomide PVX-410 0 1
Durvalumab + Lenalidomide + Rituximab Durvalumab Lenalidomide Rituximab 0 1
Elotuzumab + Lenalidomide Elotuzumab Lenalidomide 0 4
Fludarabine + Lenalidomide + Melphalan Fludarabine Lenalidomide Melphalan 0 1
Ibrutinib + Lenalidomide Ibrutinib Lenalidomide 0 3
Ibrutinib + Lenalidomide + Obinutuzumab + Prednisone + Venetoclax Ibrutinib Lenalidomide Obinutuzumab Prednisone Venetoclax 0 1
Ibrutinib + Lenalidomide + Rituximab Ibrutinib Lenalidomide Rituximab 0 8
Ipilimumab + Lenalidomide Ipilimumab Lenalidomide 0 2
Ixazomib + Lenalidomide + Rituximab Ixazomib Lenalidomide Rituximab 0 1
Lenalidomide Lenalidomide 3 22
Lenalidomide + Methylprednisolone + Ruxolitinib Lenalidomide Methylprednisolone Ruxolitinib 0 1
Lenalidomide + MOR208 Lenalidomide MOR208 0 2
Lenalidomide + MT-3724 Lenalidomide MT-3724 0 1
Lenalidomide + Nivolumab Lenalidomide Nivolumab 0 2
Lenalidomide + Nivolumab + Rituximab Lenalidomide Nivolumab Rituximab 0 1
Lenalidomide + Obinutuzumab Lenalidomide Obinutuzumab 0 1
Lenalidomide + Obinutuzumab + Polatuzumab Vedotin Lenalidomide Obinutuzumab Polatuzumab vedotin-piiq 0 1
Lenalidomide + Obinutuzumab + Venetoclax Lenalidomide Obinutuzumab Venetoclax 0 1
Lenalidomide + Ofatumumab Lenalidomide Ofatumumab 1 0
Lenalidomide + PAT-SM6 Lenalidomide PAT-SM6 0 0
Lenalidomide + Pembrolizumab Lenalidomide Pembrolizumab 0 3
Lenalidomide + Pidilizumab Lenalidomide Pidilizumab 0 1
Lenalidomide + PVX-410 Lenalidomide PVX-410 1 0
Lenalidomide + Rituximab Lenalidomide Rituximab 2 0
Lenalidomide + Rituximab + Romidepsin Lenalidomide Rituximab Romidepsin 0 1
Lenalidomide + Rituximab + Thalidomide Lenalidomide Rituximab Thalidomide 0 1
Lenalidomide + Rituximab + Venetoclax Lenalidomide Rituximab Venetoclax 0 1
Lenalidomide + Romidepsin Lenalidomide Romidepsin 0 1
Lenalidomide + SJB3-019A Lenalidomide SJB3-019A 1 0
Lenalidomide + Sonidegib Lenalidomide Sonidegib 0 1
Lenalidomide + Sorafenib Lenalidomide Sorafenib 1 0
Lenalidomide + TAK-659 Lenalidomide TAK-659 0 1
Lenalidomide + Temsirolimus Lenalidomide Temsirolimus 0 1
Lenalidomide + Vorinostat Lenalidomide Vorinostat 0 1


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