Drug Detail

Drug Name Fludarabine
Trade Name Fludara
Synonyms FAMP|Fludarabine phosphate
Drug Descriptions

Flurdara (fludarabine) is converted to 2-fluoro-ara-ATP intracellularly, which potentially inhibits DNA polymerase alpha, ribonucleotide reductase and DNA primase, leading to decreased DNA synthesis and reduced tumor growth (NCI Drug Dictionary)

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldesleukin + anti-KRAS G12D mTCR cells + Cyclophosphamide + Fludarabine Aldesleukin Cyclophosphamide Fludarabine anti-KRAS G12D mTCR cells 0 1
Aldesleukin + Anti-MAGE-A3-DP4 TCR T-cells + Cyclophosphamide + Fludarabine Aldesleukin Anti-MAGE-A3-DP4 TCR T-cells Cyclophosphamide Fludarabine 0 1
Aldesleukin + Anti-NY ESO-1 mTCR PBL + Cyclophosphamide + Fludarabine Aldesleukin Anti-NY ESO-1 mTCR PBL Cyclophosphamide Fludarabine 0 1
Aldesleukin + Anti-NY ESO-1 mTCR PBL + Cyclophosphamide + Fludarabine + NY-ESO-1 peptide vaccine Aldesleukin Anti-NY ESO-1 mTCR PBL Cyclophosphamide Fludarabine NY-ESO-1 peptide vaccine 0 1
Aldesleukin + Cyclophosphamide + Fludarabine Aldesleukin Cyclophosphamide Fludarabine 0 4
Aldesleukin + Cyclophosphamide + Fludarabine + IMA101 T cells Aldesleukin Cyclophosphamide Fludarabine IMA101 T cells 0 1
Aldesleukin + Cyclophosphamide + Fludarabine + LN-145 + Pembrolizumab Aldesleukin Cyclophosphamide Fludarabine LN-145 Pembrolizumab 0 1
Aldesleukin + Cyclophosphamide + Fludarabine + Mesna + Pembrolizumab Aldesleukin Cyclophosphamide Fludarabine Mesna Pembrolizumab 0 1
Aldesleukin + Cyclophosphamide + Fludarabine + Pembrolizumab Aldesleukin Cyclophosphamide Fludarabine Pembrolizumab 0 1
Aldesleukin + Cyclophosphamide + Fludarabine + RV-NY-ESO TCR PBMC Aldesleukin Cyclophosphamide Fludarabine RV-NY-ESO TCR PBMC 0 0
Allopurinol + Cyclophosphamide + Fludarabine Allopurinol Cyclophosphamide Fludarabine 0 1
ALT-803 + Cyclophosphamide + Fludarabine ALT-803 Cyclophosphamide Fludarabine 0 2
Anti-BCMA CAR T Cells + Cyclophosphamide + Fludarabine Anti-BCMA CAR T Cells Cyclophosphamide Fludarabine 0 1
Anti-BCMA CAR T Cells + Cyclophosphamide + Fludarabine + LY3039478 Anti-BCMA CAR T Cells Cyclophosphamide Fludarabine LY3039478 0 1
Anti-CD19/CD20 CAR T cells + Cyclophosphamide + Fludarabine Anti-CD19/CD20 CAR T cells Cyclophosphamide Fludarabine 0 1
Anti-SLAMF7 CAR T cells + Cyclophosphamide + Fludarabine Anti-SLAMF7 CAR T cells Cyclophosphamide Fludarabine 0 1
anti-thymocyte globulin + Busulfan + Fludarabine Busulfan Fludarabine anti-thymocyte globulin 0 2
anti-thymocyte globulin + Fludarabine + Melphalan Fludarabine Melphalan anti-thymocyte globulin 0 1
Azacitidine + Cytarabine + Fludarabine + MLN4924 Azacitidine Cytarabine Fludarabine MLN4924 0 1
BC8-B10 + Cyclophosphamide + Fludarabine BC8-B10 Cyclophosphamide Fludarabine 0 1
Bendamustine + Fludarabine + iC9/CAR.19/IL15-Transduced CB-NK Bendamustine Fludarabine iC9/CAR.19/IL15-Transduced CB-NK 0 1
Bendamustine + Fludarabine + inotuzumab ozogamicin Bendamustine Fludarabine inotuzumab ozogamicin 0 1
Bendamustine + Fludarabine + inotuzumab ozogamicin + Tacrolimus Bendamustine Fludarabine Tacrolimus inotuzumab ozogamicin 0 1
Bendamustine + Fludarabine + Tisagenlecleucel Bendamustine Fludarabine Tisagenlecleucel 0 1
Bortezomib + Fludarabine + Melphalan Bortezomib Fludarabine Melphalan 0 1
Busulfan + Clofarabine + Fludarabine Busulfan Clofarabine Fludarabine 0 1
Busulfan + Cyclophosphamide + Fludarabine Busulfan Cyclophosphamide Fludarabine 0 1
Busulfan + Fludarabine Busulfan Fludarabine 0 1
Busulfan + Fludarabine + Romidepsin Busulfan Fludarabine Romidepsin 0 1
Busulfan + Fludarabine + Sorafenib Busulfan Fludarabine Sorafenib 0 1
Busulfan + Fludarabine + Venetoclax Busulfan Fludarabine Venetoclax 0 1
CPX-351 + Cytarabine + Filgrastim + Fludarabine CPX-351 Cytarabine Filgrastim Fludarabine 0 1
Crenolanib + Cytarabine + Filgrastim + Fludarabine + Idarubicin + Mitoxantrone Crenolanib Cytarabine Filgrastim Fludarabine Idarubicin Mitoxantrone 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Fludarabine + Prednisone + Rituximab + Vincristine Cyclophosphamide Doxorubicin Etoposide Fludarabine Prednisone Rituximab Vincristine 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Fludarabine + Prednisone + Vincristine Cyclophosphamide Doxorubicin Etoposide Fludarabine Prednisone Vincristine 0 1
Cyclophosphamide + Fludarabine Cyclophosphamide Fludarabine 0 14
Cyclophosphamide + Fludarabine + HPVSTs + Nivolumab Cyclophosphamide Fludarabine HPVSTs Nivolumab 0 0
Cyclophosphamide + Fludarabine + Ibrutinib + Rituximab Cyclophosphamide Fludarabine Ibrutinib Rituximab 0 1
Cyclophosphamide + Fludarabine + iC9/CAR.19/IL15-Transduced CB-NK Cyclophosphamide Fludarabine iC9/CAR.19/IL15-Transduced CB-NK 0 1
Cyclophosphamide + Fludarabine + Interleukin-12 + LN-145 + Mesna Cyclophosphamide Fludarabine Interleukin-12 LN-145 Mesna 0 1
Cyclophosphamide + Fludarabine + KTE-C19 Cyclophosphamide Fludarabine KTE-C19 0 4
Cyclophosphamide + Fludarabine + Melphalan + Sirolimus Cyclophosphamide Fludarabine Melphalan Sirolimus 0 1
Cyclophosphamide + Fludarabine + Melphalan + Tacrolimus Cyclophosphamide Fludarabine Melphalan Tacrolimus 0 1
Cyclophosphamide + Fludarabine + Mycophenolate mofetil Cyclophosphamide Fludarabine Mycophenolate mofetil 0 3
Cyclophosphamide + Fludarabine + Nivolumab Cyclophosphamide Fludarabine Nivolumab 0 1
Cyclophosphamide + Fludarabine + Obinutuzumab Cyclophosphamide Fludarabine Obinutuzumab 0 1
Cyclophosphamide + Fludarabine + Ofatumumab Cyclophosphamide Fludarabine Ofatumumab 1 0
Cyclophosphamide + Fludarabine + Rituximab Cyclophosphamide Fludarabine Rituximab 0 2
Cyclophosphamide + Fludarabine + Thiotepa Cyclophosphamide Fludarabine Thiotepa 0 2
Cyclophosphamide + Fludarabine + Tisagenlecleucel Cyclophosphamide Fludarabine Tisagenlecleucel 0 3
Cyclosporine + Fludarabine + Mycophenolate mofetil + Sirolimus Cyclosporine Fludarabine Mycophenolate mofetil Sirolimus 0 1
Cytarabine + Dasatinib + Fludarabine + Idarubicin Cytarabine Dasatinib Fludarabine Idarubicin 0 1
Cytarabine + Daunorubicin + Fludarabine Cytarabine Daunorubicin Fludarabine 0 1
Cytarabine + Daunoxome + Fludarabine Cytarabine Daunoxome Fludarabine 0 1
Cytarabine + Filgrastim + Fludarabine Cytarabine Filgrastim Fludarabine 0 1
Cytarabine + Filgrastim + Fludarabine + Gemtuzumab ozogamicin Cytarabine Filgrastim Fludarabine Gemtuzumab ozogamicin 0 1
Cytarabine + Filgrastim + Fludarabine + Gemtuzumab ozogamicin + Idarubicin Cytarabine Filgrastim Fludarabine Gemtuzumab ozogamicin Idarubicin 0 1
Cytarabine + Filgrastim + Fludarabine + Idarubicin + Mitoxantrone Cytarabine Filgrastim Fludarabine Idarubicin Mitoxantrone 0 1
Cytarabine + Filgrastim + Fludarabine + Idarubicin + Venetoclax Cytarabine Filgrastim Fludarabine Idarubicin Venetoclax 0 1
Cytarabine + Fludarabine Cytarabine Fludarabine 0 2
Cytarabine + Fludarabine + Idarubicin Cytarabine Fludarabine Idarubicin 0 4
Cytarabine + Fludarabine + Idarubicin + Uproleselan Cytarabine Fludarabine Idarubicin Uproleselan 0 1
Cytarabine + Fludarabine + Leucovorin + Panobinostat Cytarabine Fludarabine Leucovorin Panobinostat 0 1
Cytarabine + Fludarabine + Methotrexate + Prednisone + Selinexor Cytarabine Fludarabine Methotrexate Prednisone Selinexor 0 1
Cytarabine + Fludarabine + Prexasertib Cytarabine Fludarabine Prexasertib 0 1
Dasatinib + Fludarabine + Rituximab Dasatinib Fludarabine Rituximab 0 1
Doxorubicin + Etoposide + Fludarabine + Vincristine Doxorubicin Etoposide Fludarabine Vincristine 0 1
Fludarabine Fludarabine 0 31
Fludarabine + Ibrutinib Fludarabine Ibrutinib 0 1
Fludarabine + Ibrutinib + Pembrolizumab Fludarabine Ibrutinib Pembrolizumab 0 1
Fludarabine + inotuzumab ozogamicin + Melphalan + Tacrolimus Fludarabine Melphalan Tacrolimus inotuzumab ozogamicin 0 1
Fludarabine + Iomab-B Fludarabine Iomab-B 0 1
Fludarabine + Lenalidomide + Melphalan Fludarabine Lenalidomide Melphalan 0 1
Fludarabine + Melphalan Fludarabine Melphalan 0 8
Fludarabine + Olaparib Fludarabine Olaparib 1 0


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