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Drug Name MGTA-456
Trade Name
Synonyms MGTA 456|Spanlecortemlocel|HSC835
Drug Descriptions

MGTA-456 consists of a preparation of a cord blood cells expanded with an aryl hydrocarbon receptor antagonist, which may result in improved microglial engraftment and immune recovery (Neurology Apr 2019, 92 (15 Supplement) S51.001).

DrugClasses
CAS Registry Number NA
NCIT ID C111571

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Busulfan + Filgrastim + Fludarabine + Melphalan + MGTA-456 + Mycophenolate mofetil + Tacrolimus Busulfan Filgrastim Fludarabine MGTA-456 Melphalan Mycophenolate mofetil Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Fludarabine + MGTA-456 + Mycophenolate mofetil + Tacrolimus Cyclophosphamide Filgrastim Fludarabine MGTA-456 Mycophenolate mofetil Tacrolimus 0 1
MGTA-456 MGTA-456 0 0


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