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Drug Name MGTA-456
Trade Name
Synonyms MGTA 456|Spanlecortemlocel|HSC835
Drug Descriptions

MGTA-456 consists of a preparation of a cord blood cells expanded with an aryl hydrocarbon receptor antagonist, which may result in improved microglial engraftment and immune recovery (Neurology Apr 2019, 92 (15 Supplement) S51.001).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
Busulfan + Filgrastim + Fludarabine + Melphalan + MGTA-456 + Mycophenolate mofetil + Tacrolimus Busulfan Filgrastim Fludarabine MGTA-456 Melphalan Mycophenolate mofetil Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Fludarabine + MGTA-456 + Mycophenolate mofetil + Tacrolimus Cyclophosphamide Filgrastim Fludarabine MGTA-456 Mycophenolate mofetil Tacrolimus 0 1
MGTA-456 MGTA-456 0 0

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