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Drug Name Tacrolimus
Trade Name Hecoria
Synonyms FK-506|Prograf|Advagraf
Drug Descriptions

Tacrolimus binds to FKBP-12 and inhibits calcineurin activity, resulting in immunosuppression (NCI Drug Dictionary).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bendamustine + Fludarabine + Inotuzumab ozogamicin + Tacrolimus Bendamustine Fludarabine Inotuzumab ozogamicin Tacrolimus 0 1
Busulfan + Clofarabine + Cyclophosphamide + Gemcitabine + Mycophenolate mofetil + Rituximab + Tacrolimus + Vorinostat Busulfan Clofarabine Cyclophosphamide Gemcitabine Mycophenolate mofetil Rituximab Tacrolimus Vorinostat 0 1
Busulfan + Clofarabine + Cyclophosphamide + Gemcitabine + Mycophenolate mofetil + Tacrolimus + Vorinostat Busulfan Clofarabine Cyclophosphamide Gemcitabine Mycophenolate mofetil Tacrolimus Vorinostat 0 1
Busulfan + Filgrastim + Fludarabine + Melphalan + MGTA-456 + Mycophenolate mofetil + Tacrolimus Busulfan Filgrastim Fludarabine MGTA-456 Melphalan Mycophenolate mofetil Tacrolimus 0 1
Busulfan + Fludarabine + GVAX + Methotrexate + Tacrolimus Busulfan Fludarabine GVAX Methotrexate Tacrolimus 0 1
Busulfan + Fludarabine + Methotrexate + Tacrolimus Busulfan Fludarabine Methotrexate Tacrolimus 0 1
CD45RA-depleted donor lymphocytes + Cyclophosphamide + Filgrastim + Fludarabine + Melphalan + Tacrolimus CD45RA-depleted donor lymphocytes Cyclophosphamide Filgrastim Fludarabine Melphalan Tacrolimus 0 0
Cyclophosphamide + Daratumumab + Mycophenolate mofetil + Tacrolimus Cyclophosphamide Daratumumab Mycophenolate mofetil Tacrolimus 0 1
Cyclophosphamide + ECT-001 cord blood cells + Fludarabine + Mycophenolate mofetil + Tacrolimus Cyclophosphamide ECT-001 cord blood cells Fludarabine Mycophenolate mofetil Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Fludarabine + MGTA-456 + Mycophenolate mofetil + Tacrolimus Cyclophosphamide Filgrastim Fludarabine MGTA-456 Mycophenolate mofetil Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Mycophenolate mofetil + Sirolimus + Tacrolimus Cyclophosphamide Filgrastim Mycophenolate mofetil Sirolimus Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Mycophenolate mofetil + Tacrolimus + Testosterone cypionate Cyclophosphamide Filgrastim Mycophenolate mofetil Tacrolimus Testosterone cypionate 0 1
Cyclophosphamide + Fludarabine + Melphalan + Tacrolimus Cyclophosphamide Fludarabine Melphalan Tacrolimus 0 1
Cyclosporine + Mycophenolate mofetil + Tacrolimus Cyclosporine Mycophenolate mofetil Tacrolimus 0 1
Everolimus + Tacrolimus Everolimus Tacrolimus 0 0
Filgrastim + Mycophenolate mofetil + Tacrolimus Filgrastim Mycophenolate mofetil Tacrolimus 0 2
Fludarabine + Inotuzumab ozogamicin + Melphalan + Tacrolimus Fludarabine Inotuzumab ozogamicin Melphalan Tacrolimus 0 1
Ipilimumab + Nivolumab + Prednisone + Tacrolimus Ipilimumab Nivolumab Prednisone Tacrolimus 0 1
Methotrexate + Sirolimus + Tacrolimus Methotrexate Sirolimus Tacrolimus 0 3
Methotrexate + Tacrolimus Methotrexate Tacrolimus 0 2
Mycophenolate mofetil + Tacrolimus Mycophenolate mofetil Tacrolimus 0 0
Ruxolitinib + Sirolimus + Tacrolimus Ruxolitinib Sirolimus Tacrolimus 0 1
Tacrolimus Tacrolimus 0 22


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