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Drug Name Clofarabine
Trade Name Clolar
Synonyms Clofarex
Drug Descriptions

Clolar (clofarabine) is a purine nucleoside analog that inhibits ribonucleotide reductase and DNA polymerase, preventing DNA synthesis and repair, and induces apoptosis by inhibiting mitochondrial function (NCI Drug Dictionary).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
anti-thymocyte globulin + Busulfan + Clofarabine Busulfan Clofarabine anti-thymocyte globulin 0 3
anti-thymocyte globulin + Busulfan + Clofarabine + Fludarabine + haNK cells Busulfan Clofarabine Fludarabine anti-thymocyte globulin haNK cells 0 1
Bortezomib + Clofarabine Bortezomib Clofarabine 0 1
Busulfan + Clofarabine + Cyclophosphamide + Gemcitabine + Mycophenolate mofetil + Rituximab + Tacrolimus + Vorinostat Busulfan Clofarabine Cyclophosphamide Gemcitabine Mycophenolate mofetil Rituximab Tacrolimus Vorinostat 0 1
Busulfan + Clofarabine + Cyclophosphamide + Gemcitabine + Mycophenolate mofetil + Tacrolimus + Vorinostat Busulfan Clofarabine Cyclophosphamide Gemcitabine Mycophenolate mofetil Tacrolimus Vorinostat 0 1
Busulfan + Clofarabine + Fludarabine Busulfan Clofarabine Fludarabine 0 1
Busulfan + Clofarabine + Gemcitabine Busulfan Clofarabine Gemcitabine 0 1
Clofarabine Clofarabine 0 9
Clofarabine + Cyclophosphamide + Etoposide Clofarabine Cyclophosphamide Etoposide 0 1
Clofarabine + Cytarabine + Dexamethasone + Idarubicin + Rituximab + Vincristine Sulfate Clofarabine Cytarabine Dexamethasone Idarubicin Rituximab Vincristine Sulfate 0 1
Clofarabine + Cytarabine + Dexamethasone + Idarubicin + Sorafenib + Vincristine Sulfate Clofarabine Cytarabine Dexamethasone Idarubicin Sorafenib Vincristine Sulfate 0 1
Clofarabine + Cytarabine + Dexamethasone + Idarubicin + Vincristine Sulfate Clofarabine Cytarabine Dexamethasone Idarubicin Vincristine Sulfate 0 1
Clofarabine + Cytarabine + Sorafenib Clofarabine Cytarabine Sorafenib 0 1
Clofarabine + Edelfosine + Gemcitabine Clofarabine Edelfosine Gemcitabine 0 0
Clofarabine + Melphalan Clofarabine Melphalan 0 1


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